[1]邹克平.超声实时剪切波弹性成像对血吸虫病肝纤维化的诊断效能分析[J].医学信息,2022,35(18):150-152.[doi:10.3969/j.issn.1006-1959.2022.18.042]
 ZOU Ke-ping.Analysis of Diagnostic Efficacy of Ultrasound Shear Wave Elastography in Schistosomiasis Liver Fibrosis[J].Journal of Medical Information,2022,35(18):150-152.[doi:10.3969/j.issn.1006-1959.2022.18.042]
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超声实时剪切波弹性成像对血吸虫病肝纤维化的诊断效能分析()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
35卷
期数:
2022年18期
页码:
150-152
栏目:
诊疗技术
出版日期:
2022-09-15

文章信息/Info

Title:
Analysis of Diagnostic Efficacy of Ultrasound Shear Wave Elastography in Schistosomiasis Liver Fibrosis
文章编号:
1006-1959(2022)18-0150-03
作者:
邹克平
(永修县疾病预防控制中心B超室,江西 永修 330303)
Author(s):
ZOU Ke-ping
(Ultra-sound radiography Room of Yongxiu County Center for Disease Control and Prevention,Yongxiu 330303,Jiangxi, China)
关键词:
肝纤维化超声剪切波弹性成像血吸虫病
Keywords:
Liver fibrosisUltrasound shear wave elastographySchistosomiasis
分类号:
R445.1
DOI:
10.3969/j.issn.1006-1959.2022.18.042
文献标志码:
A
摘要:
目的 评价超声实时剪切波弹性成像对血吸虫病肝纤维化的诊断效能。方法 选取2019年8月-2021年7月永修县疾病预防控制中心超声科治疗的68例血吸虫病肝纤维化患者作为研究对象,根据纤维化分期分为S0(n=15)、S1(n=12)、S2(n=13)、S3(n=12)、S4(n=15)分期组。所有患者均行超声实时剪切波弹性成像,比较各组肝纤维化参数、弹性模量参数,并分析弹性模量参数对肝纤维化病理分期的诊断价值。结果 S1、S2、S3、S4分期组弹性模量、层黏连蛋白、透明质酸高于S0分期组,差异有统计学意义(P<0.05);S1、S2、S3、S4分期组Ⅳ型胶原、Ⅲ型前胶原高于S0分期组,但差异无统计学意义(P>0.05);肝实质弹性模量对肝纤维化S1~S4期的诊断效能最高(AUC=0.952,P<0.05)。结论 血吸虫病肝纤维化患者超声实时剪切波弹性成像参数对病理分期诊断有较高价值,同时具有无创、准确等优点。
Abstract:
Objective To evaluate the diagnostic efficiency of ultrasound shear wave elastography in schistosomiasis liver fibrosis.Methods A total of 68 patients with schistosomiasis liver fibrosis treated by Yongxiu County Center for Disease Control and Prevention from August 2019 to July 2021 were selected as the research objects. According to the fibrosis stage, they were divided into S0 (n=15), S1 (n=12), S2 (n=13), S3 (n=12) and S4 (n=15) staging groups. All patients underwent ultrasound shear wave elastography. The liver fibrosis parameters and elastic modulus parameters of each group were compared, and the diagnostic value of elastic modulus parameters for pathological staging of liver fibrosis was analyzed.Results The elastic modulus, laminin and hyaluronic acid in S1, S2, S3 and S4 staging groups were higher than those in S0 staging group, and the differences were statistically significant (P<0.05). Type Ⅳ collagen and type Ⅲ procollagen in S1, S2, S3 and S4 staging groups were higher than those in S0 staging group, but the difference was not statistically significant (P>0.05). The elastic modulus of liver parenchyma had the highest diagnostic efficiency for S1-S4 stage of liver fibrosis (AUC=0.952, P<0.05).Conclusion Ultrasound shear wave elastography parameters in patients with schistosomiasis liver fibrosis have high value in pathological staging diagnosis, and have the advantages of non-invasive and accurate.

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更新日期/Last Update: 1900-01-01