[1]陈小毛.经尿道前列腺电切术对前列腺增生症所致尿路梗阻的治疗效果及安全性分析[J].医学信息,2022,35(19):109-111.[doi:10.3969/j.issn.1006-1959.2022.19.030]
　CHEN Xiao-mao.Therapeutic Effect and Safety of Transurethral Resection of Prostate on Urinary Tract Obstruction Caused by Benign Prostatic Hyperplasia[J].Journal of Medical Information,2022,35(19):109-111.[doi:10.3969/j.issn.1006-1959.2022.19.030]
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经尿道前列腺电切术对前列腺增生症所致尿路梗阻的治疗效果及安全性分析()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
35卷
期数:
2022年19期
页码:
109-111
栏目:
临床研究
出版日期:
2022-10-01

文章信息/Info

Title:
Therapeutic Effect and Safety of Transurethral Resection of Prostate on Urinary Tract Obstruction Caused by Benign Prostatic Hyperplasia
文章编号:
1006-1959（2022）19-0109-03
作者:
陈小毛
（峡江县人民医院外一科，江西 峡江 331400）
Author(s):
CHEN Xiao-mao
(The First Department of Surgery,Xiajiang County People’s Hospital,Xiajiang 331400,Jiangxi,China)
关键词:
前列腺增生症; 尿路梗阻; 经尿道前列腺电切术
Keywords:
Prostatic hyperplasia; Urinary tract obstruction; Transurethral resection of prostate
分类号:
R699.8
DOI:
10.3969/j.issn.1006-1959.2022.19.030
文献标志码:
A
摘要:
目的 探讨前列腺增生症所致尿路梗阻应用经尿道前列腺电切术的治疗效果及安全性。方法 选择2018年3月-2020年9月本院收治的60例尿路梗阻患者，随机分为观察组和对照组，各30例。术前及术后7 d比较两组国际前列腺症状评分表（I-PSS评分）、最大尿流率（MFR）、尿流时间（TT）、总排尿量（VV）、血清前列腺特异性抗原（PSA）、神经元特异性烯醇化酶（NSE）及治疗安全性。结果 两组术后7 d I-PSS评分、TT、PSA低于治疗前，且观察组低于对照组，差异有统计学意义（P＜0.05）；两组MFR、VV高于治疗前，且观察组高于对照组，差异有统计学意义（P＜0.05）；两组NSE水平高于治疗前，但观察组低于对照组，差异有统计学意义（P＜0.05）；观察组并发症发生率（10.00%）低于对照组（30.00%），差异有统计学意义（P＜0.05）。结论 前列腺增生症所致尿路梗阻应用经尿道前列腺电切术治疗效果确切，可减轻前列腺增生症状，改善尿流率，且不会引起强烈的炎性反应，对性功能影响小，安全性高。
Abstract:
Objective To investigate the efficacy and safety of transurethral resection of prostate (TURP) in the treatment of urinary tract obstruction caused by benign prostatic hyperplasia (BPH).Methods Sixty patients with urinary tract obstruction admitted to our hospital from March 2018 to September 2020 were randomly divided into observation group and control group, with 30 cases in each group. The international prostate symptom score (IPSS score), maximum urinary flow rate (MFR), urinary flow time (TT), total voiding volume (VV), serum prostate specific antigen (PSA), neuron specific enolase (NSE) and treatment safety were compared between the two groups before and 7 days after operation.Results The IPSS score, TT and PSA of the two groups at 7 d after operation were lower than those before treatment, and those in the observation group were lower than those in the control group, the differences were statistically significant (P<0.05). The MFR and VV of the two groups were higher than those before treatment, and those in the observation group were higher than those in the control group, the difference was statistically significant (P<0.05). The level of NSE in the two groups was higher than that before treatment, but that in the observation group was lower than the control group, the difference was statistically significant (P<0.05). The incidence of complications in the observation group was 10.00%, which was lower than 30.00% in the control group, and the difference was statistically significant (P<0.05).Conclusion Transurethral resection of prostate is effective in the treatment of urinary tract obstruction caused by benign prostatic hyperplasia, which can reduce the symptoms of benign prostatic hyperplasia, improve urinary flow rate, and will not cause strong inflammatory reaction, with little effect on sexual function and high safety.

参考文献/References:

[1]中国研究型医院学会泌尿外科学专业委员会,中国医疗保健国际交流促进会泌尿健康促进分会,中国医疗保健国际交流促进会循证医学分会,等.中国良性前列腺增生症经尿道等离子双极电切术治疗指南(2018简化版)[J].现代泌尿外科杂志,2018,23(9):651-654,704.[2]刘洪久,郭磊,陈延,等.经尿道前列腺等离子双极电切术治疗良性前列腺增生对患者血清PSA、PGI2水平及术后性功能、生活质量的影响[J].中国性科学,2021,30(1):15-18.[3]张翼飞,尹水平,梁朝朝.绿激光治疗前列腺增生术后下尿路梗阻症状复发的手术技巧及疗效探讨[J].现代泌尿生殖肿瘤杂志,2020,12(2):98-100.[4]胡海峰,杨进,汪自力,等.保守疗法和同期微创手术治疗前列腺增生合并输尿管结石的疗效及其对性功能的影响[J].川北医学院学报,2020,35(1):96-99.[5]吴铁球,汪志民,唐智旺.经尿道前列腺汽化电切除联合钬激光碎石手术治疗前列腺增生合并膀胱结石患者的效果及安全性[J].中华老年多器官疾病杂志,2019,18(1):51-53.[6]曾宪涛,李胜,龚侃,等.良性前列腺增生症临床诊治实践指南的循证评价[J].中华医学杂志,2017,97(22):1683-1687.[7]Basha SZ,Mohamed GA,Abdel-Naim AB,et al.Cucurbitacin E glucoside from Citrullus colocynthis inhibits testosterone-induced benign Prostatic hyperplasia in mice[J].Drug and Chemical Toxicology,2021,44(5):533-543.[8]熊标,夏丁,曹鹏,等.等离子电切术治疗前列腺囊肿1例报告[J].现代泌尿生殖肿瘤杂志,2017,9(2):118.[9]杨杰.经尿道柱状水囊前列腺扩开术与电切术治疗老年前列腺增生的效果对比[J].安徽医药,2021,25(7):1363-1366.[10]刘洪明,田野,苏志勇,等.前列腺总体积及移行带体积对良性前列腺增生症经尿道前列腺电切术疗效的影响[J].中华医学杂志,2021,101(2):137-141.[11]Kachru N,Holmes HM,Johnson ML,et al.Antimuscarinic use among older adults with dementia and overactive bladder: a Medicare beneficiaries study[J].Curr Med Res Opin,2021,37(8):1303-1313.[12]熊敏,张珩,李涛,等.良性前列腺增生患者行经尿道前列腺电切术治疗是否有效的临床预测模型[J].中国性科学,2021,30(6):4-7.[13]辛黎明.经尿道前列腺等离子剜除术与电切术治疗前列腺增生的效果比较[J].中国医药导刊,2021,23(5):329-331.[14]He J,Yi M,Tan L,et al.The immune checkPoint regulator PD-L1 exPression are associated with clinical Progression in Prostate cancer[J].World J Surg Oncol,2021,19(1):115-121.[15]姜小琴,李惠珍.经尿道膀胱肿瘤电切术同期经尿道前列腺电切术治疗非浸润性膀胱癌伴良性前列腺增生的安全性及有效性研究[J].临床外科杂志,2021,29(9):872-875.[16]李成柏,陈卫国,丁炜宏,等.经皮膀胱造瘘钬激光碎石术联合经尿道前列腺等离子电切术治疗良性前列腺增生合并膀胱结石的临床效果[J].广西医学,2021,43(7):794-798.[17]顾鑫,景立伟,王岸迪,等.经尿道前列腺等离子电切术联合前列逐癃汤对良性前列腺增生患者生活质量及术后性功能的影响[J].医学综述,2021,27(18):3711-3716.[18]林丛,梁志会,李亮,等.前列腺动脉栓塞术与经尿道前列腺等离子电切术治疗前列腺增生的临床疗效[J].局解手术学杂志,2021,30(9):800-803.

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更新日期/Last Update: 1900-01-01