[1]林 苗,余怡红,徐丽红.罗红霉素、保妇康栓联合乳酸菌阴道胶囊序贯治疗混合感染性阴道炎的临床疗效[J].医学信息,2022,35(20):124-126.[doi:10.3969/j.issn.1006-1959.2022.20.033]
　LIN Miao,YU Yi-hong,XU Li-hong.Clinical Efficacy of Roxithromycin, Baofukang Suppository Combined with Lactobacillus Vaginal Capsule in Sequential Treatment of Mixed Infectious Vaginitis[J].Journal of Medical Information,2022,35(20):124-126.[doi:10.3969/j.issn.1006-1959.2022.20.033]
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罗红霉素、保妇康栓联合乳酸菌阴道胶囊序贯治疗混合感染性阴道炎的临床疗效()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
35卷
期数:
2022年20期
页码:
124-126
栏目:
药物与临床
出版日期:
2022-10-15

文章信息/Info

Title:
Clinical Efficacy of Roxithromycin, Baofukang Suppository Combined with Lactobacillus Vaginal Capsule in Sequential Treatment of Mixed Infectious Vaginitis
文章编号:
1006-1959（2022）20-0124-03
作者:
林 苗; 余怡红; 徐丽红
（上饶市广信区人民医院妇产科，江西 上饶 334000）
Author(s):
LIN Miao; YU Yi-hong; XU Li-hong
(Department of Obstetrics and Gynecology,Guangxin District People’s Hospital,Shangrao 334000,Jiangxi,China)
关键词:
混合感染性阴道炎; 罗红霉素; 保妇康栓; 乳酸菌阴道胶囊; 阴道微环境
Keywords:
Mixed infectious vaginitis; Roxithromycin; Baofukang suppository; Lactobacillus vaginal capsules; Vaginal microenvironment
分类号:
R711.31
DOI:
10.3969/j.issn.1006-1959.2022.20.033
文献标志码:
A
摘要:
目的 研究罗红霉素、保妇康栓联合乳酸菌阴道胶囊序贯治疗混合感染性阴道炎的临床疗效。方法 采用随机数字表法将2019年1月-2021年8月上饶市广信区人民医院收治的66例混合感染性阴道炎病例分为对照组（33例）与观察组（33例）。对照组给予罗红霉素联合保妇康栓治疗，观察组给予罗红霉素、保妇康栓联合乳酸菌阴道胶囊序贯治疗，比较两组综合疗效、症状改善时间、Nugent评分、阴道pH值、阴道清洁度及复发情况。结果 观察组治疗有效率高于对照组（P＜0.05）；观察组症状改善（外阴瘙痒、白带异味、白带增多、阴道灼痛）时间短于对照组（P＜0.05）；两组治疗后Nugent评分、阴道pH值均下降，且观察组低于对照组（P＜0.05）；观察组阴道清洁度正常率高于对照组（P＜0.05）。治疗后3个月，观察组复发率为3.03%，低于对照组的18.18%（P＜0.05）。结论 罗红霉素、保妇康栓联合乳酸菌阴道胶囊序贯治疗混合感染性阴道炎效果确切，可缩短患者症状改善时间，纠正阴道菌群失衡，改善阴道pH值及清洁度，降低复发风险。
Abstract:
Objective To study the clinical effect of sequential therapy of roxithromycin, Baofukang suppository and lactobacillus vaginal capsule on mixed infectious vaginitis.Methods A total of 66 cases of mixed infectious vaginitis admitted to Guangxin District People’s Hospital of Shangrao City from January 2019 to August 2021 were divided into control group (33 cases) and observation group (33 cases) by random number table method. The control group was treated with roxithromycin combined with Baofukang suppository, and the observation group was treated with roxithromycin, Baofukang suppository combined with lactobacillus vaginal capsule sequential therapy.The comprehensive efficacy, symptom improvement time, Nugent score, vaginal pH value, vaginal cleanliness and recurrence were compared between the two groups.Results The effective rate of treatment in the observation group was higher than that in the control group (P<0.05). The symptom improvement time (vulva pruritus, leucorrhea odor, leucorrhea increase, vaginal burning pain) in the observation group was shorter than that in the control group (P<0.05). After treatment, the Nugent score and vaginal pH value of the two groups decreased, and those in the observation group were lower than the control group (P<0.05). The normal rate of vaginal cleanliness in the observation group was higher than that in the control group (P<0.05). Three months after treatment, the recurrence rate of the observation group was 3.03%, which was lower than 18.18% of the control group (P<0.05).Conclusion The sequential treatment of roxithromycin, Baofukang suppository combined with lactobacillus vaginal capsule is effective in the treatment of mixed infectious vaginitis. It can shorten the time of symptom improvement, correct the imbalance of vaginal flora, improve vaginal pH and cleanliness, and reduce the risk of recurrence.

参考文献/References:

[1]汪敏,方小岳,邱淑芬.乳酸菌阴道胶囊联合抗菌治疗老年性阴道炎对血清性激素和相关元素水平的影响[J].中国妇幼保健,2021,36(5):1009-1011.[2]邱曙光,王志伟.300例支原体性阴道炎合并病原微生物感染分析[J].中国医药科学,2019,9(20):174-177.[3]雷曼,赵小丽,乌日娜.阴道用乳杆菌活菌胶囊联合妇阴康洗剂治疗混合性阴道炎的疗效观察[J].药物评价研究,2020,43(12):2509-2512.[4]郑顺杰,胡益飞,胡旻,等.妇科门诊阴道炎的病原菌特点及影响因素分析[J].中国卫生检验杂志,2020,30(21):2674-2676.[5]Wang Y.Clinical Observation on the Treatment of Mixed Infectious Vaginitis with Roxithromycin and Baofukang Suppository Combined with Lactic Acid Bacteria and Vaginal Capsule[J].Guide of China Medicine,2017,37(14):1912-1914.[6]张晶,魏恒,张慧杰.保妇康栓联合硝呋太尔制霉菌素栓改善萎缩性阴道炎患者阴道镜检查效果的临床分析[J].实用药物与临床,2017,20(6):676-678.[7]洪艺婷.乳酸菌阴道胶囊与雌激素联合治疗老年性阴道炎的临床效果研究[J].中外医学研究,2020,18(6):37-39.[8]吴晓燕,宋莹莹,马利平.乳酸菌阴道胶囊联合戊酸雌二醇对老年性阴道炎患者阴道分泌物IL-6、TNF-α、IL-8的影响[J].中国医师杂志,2017,19(12):1893-1895.[9]中华医学会妇产科学分会感染性疾病协作组,刘朝晖.混合性阴道炎诊治专家共识(2021版)[J].中华妇产科杂志,2021,56(1):15-18.[10]李艳梅,贺雯,欧洁贤,等.乳酸菌阴道胶囊联合氟康唑治疗念珠菌性阴道炎的疗效及对阴道菌群的影响[J].海南医学,2019,30(19):2521-2524.[11]李飞飞,余丽金,曾雪英.乳酸菌阴道胶囊联合雌激素治疗对老年阴道炎病人炎症因子和阴道微生态的影响[J].实用老年医学,2019,33(2):137-140.[12]Wang ZL,Fu LY,Xiong ZA,et al.Diagnosis and microecological characteristics of aerobic vaginitis in outpatients based on preformed enzymes[J].Taiwanese Journal of Obstetrics and Gynecology,2016,55(1):40-44.[13]胡令军,刘芳.氟康唑联合保妇康栓治疗霉菌性阴道炎的临床疗效[J].中国妇幼保健,2018,33(10):2228-2229.[14]周明锐,李杰,路峥,等.保妇康栓联合小剂量雌激素对老年阴道炎血清雌激素水平及生活质量的影响[J].现代生物医学进展,2020,20(18):3494-3497.[15]童鑫,唐燕燕,唐喆,等.保妇康栓联合雌激素治疗老年性阴道炎的系统评价[J].中南药学,2016,14(12):1380-1386.[16]自蓉,张洁,叶珂帆,等.外阴疾病患者阴道微生态状况及其影响因素[J].山东医药,2017,57(20):87-89.[17]王芳,霍彦,刘艳妍,等.不同给药方法治疗细菌性阴道病对阴道微生态环境及免疫因子表达的影响[J].天津医药,2016,44(8):1029-1032,1060.[18]蒋莉莉,施素华,邬小龙.影响阴道炎复发因素的临床分析[J].现代仪器与医疗,2016,22(3):94-96.[19]陈玲,林涛.乳酸菌阴道胶囊联合戊酸雌二醇治疗老年性阴道炎疗效观察[J].中国性科学,2016,25(6):64-66.

更新日期/Last Update: 1900-01-01