[1]符仲标,陈 琼,卓晓春,等.血清腹水白蛋白梯度检测的临床意义[J].医学信息,2022,35(21):150-152.[doi:10.3969/j.issn.1006-1959.2022.21.040]
　FU Zhong-biao,CHEN Qiong,ZHUO Xiao-chun,et al.Clinical Significance of Serum Ascites Albumin Gradient Detection[J].Journal of Medical Information,2022,35(21):150-152.[doi:10.3969/j.issn.1006-1959.2022.21.040]
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血清腹水白蛋白梯度检测的临床意义()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
35卷
期数:
2022年21期
页码:
150-152
栏目:
诊疗技术
出版日期:
2022-11-01

文章信息/Info

Title:
Clinical Significance of Serum Ascites Albumin Gradient Detection
文章编号:
1006-1959（2022）21-0150-03
作者:
符仲标; 陈 琼; 卓晓春; 等
（海南医学院第二附属医院消化内科1，感染科2，介入科3，海南 海口 570311）
Author(s):
FU Zhong-biao; CHEN Qiong; ZHUO Xiao-chun; et al.
(Department of Gastroenterology1,Department of Infection2,Department of Intervention3,the Second Affiliated Hospital ofHainan Medical University,Haikou 570311,Hainan,China)
关键词:
血清腹水白蛋白; 梯度检测; 门静脉高压; 非门静脉高压
Keywords:
Serum ascites albumin; Gradient detection; Portal hypertension; Non-portal hypertension
分类号:
R446.19
DOI:
10.3969/j.issn.1006-1959.2022.21.040
文献标志码:
A
摘要:
目的 探讨血清腹水白蛋白梯度（SAAG）检测的临床意义。方法 选取本院2018年1月-2019年12月收治的100例腹水患者，根据腹水发生机制分为门静脉高压组（48例）和非门静脉高压组（52例）。比较两组SAAG水平，不同SAAG水平（≥11 g/L、＜11 g/L）的食管静脉曲张数、SAAG检测与传统渗漏出液分类法诊断门静脉高压性腹水的准确率以及SAAG水平与肝功能分级（Child 分级）的关系。结果 门静脉高压组SAAG水平高于非门静脉高压组，差异有统计学意义（P＜0.05）；SAAG诊断门静脉高压腹水的准确率高于传统渗漏出液分类法，差异有统计学意义（P＜0.05）；SAAG≥11 g/L的患者中食管静脉曲张比例高于SAAG＜11 g/L的患者，差异有统计学意义（P＜0.05）；SAAG≥11 g/L的患者肝功能分级比SAAG＜11 g/L的患者差，差异有统计学意义（P＜0.05）。结论 SAAG检测在腹水中的临床意义高，SAAG水平越高患者肝功能受损越严重；同时，SAAG检测操作较为简单且影响因素较少，具有较强的操作性，可有效鉴别诊断门静脉高压腹水和非门静脉高压腹水。
Abstract:
Objective To investigate the clinical significance of serum ascites albumin gradient (SAAG) detection.Methods A total of 100 patients with ascites admitted to our hospital from January 2018 to December 2019 were selected and divided into portal hypertension group (48 cases) and non-portal hypertension group (52 cases) according to the mechanism of ascites. The SAAG level, the number of esophageal varices with different SAAG levels (≥11 g/L, <11 g/L), the accuracy of SAAG detection and traditional leakage fluid classification in the diagnosis of portal hypertensive ascites, and the relationship between SAAG level and liver function classification (Child classification) were compared between the two groups.Results SAAG level in portal hypertension group was higher than that in non-portal hypertension group, and the difference was statistically significant (P<0.05). The accuracy of SAAG in the diagnosis of ascites due to portal hypertension was higher than that of traditional leakage fluid classification, and the difference was statistically significant (P<0.05). The proportion of esophageal varices in patients with SAAG≥11 g/L was higher than that in patients with SAAG<11 g/L, and the difference was statistically significant (P<0.05). The liver function classification of patients with SAAG≥11 g/L was worse than that of patients with SAAG<11 g/L, and the difference was statistically significant (P<0.05).Conclusion SAAG test has high clinical significance in ascites. The higher the level of SAAG, the more serious the liver function impairment. At the same time, SAAG detection is simple and has fewer influencing factors, and has strong operability, which can effectively differentiate the diagnosis of portal hypertensive ascites from non-portal hypertensive ascites.

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更新日期/Last Update: 1900-01-01