[1]黄思颖,郭铭娜,邹倩倩,等.基于CiteSpace干细胞神经元修复的可视化分析[J].医学信息,2023,36(13):24-30.[doi:10.3969/j.issn.1006-1959.2023.13.005]
　HUANG Si-ying,GUO Ming-na,ZOU Qian-qian,et al.Visual Analysis of Stem Cells Neuron Repair Based on CiteSpace[J].Journal of Medical Information,2023,36(13):24-30.[doi:10.3969/j.issn.1006-1959.2023.13.005]
点击复制

基于CiteSpace干细胞神经元修复的可视化分析()
分享到：

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
36卷
期数:
2023年13期
页码:
24-30
栏目:
医学数据科学
出版日期:
2023-07-01

文章信息/Info

Title:
Visual Analysis of Stem Cells Neuron Repair Based on CiteSpace
文章编号:
1006-1959（2023）13-0024-07
作者:
黄思颖; 郭铭娜; 邹倩倩; 等
（惠州学院生命科学学院，广东 惠州 516007）
Author(s):
HUANG Si-ying; GUO Ming-na; ZOU Qian-qian; et al.
(School of Life Sciences,Huizhou University,Huizhou 516007,Guangdong,China)
关键词:
神经元; 干细胞修复; 文献计量法; CiteSpace; 可视化分析
Keywords:
Neuron; Stem cell repair; Bibliometric method; CiteSpace; Visualanalysis
分类号:
R651
DOI:
10.3969/j.issn.1006-1959.2023.13.005
文献标志码:
A
摘要:
目的 总结国内外对干细胞神经元修复的研究现状及发展趋势，为后续该领域的研究提供参考。方法 以Web of Science数据库中主题词为stem cell neural repair*，时间范围为2012-2021年的2729篇文献为研究对象，运用CiteSpace软件，通过文献计量法对干细胞神经元修复研究的发文量年代分布、关键词突现等进行可视化分析。结果 文献发文量的年度分布主要呈现4个阶段，总体呈上升趋势；亚洲、美州和欧洲的作者发表论文的数量居多，其中亚洲以我国为代表发文量有1070篇，占论文发文量的34.30%；干细胞神经元修复的高频关键词为“neural stem cell”“stem cell”等；聚类网络共形成axonal regeneration、Parkinsons disease等22个聚类；“central nervous system”的突现强度最大；轴突再生、帕金森病、细胞分化等领域的研究时间较长；文献共被引中引用最多的文献是“Cell transplantation therapy for spinal cord injury”，共被引频次为57次。结论 干细胞神经元修复的相关研究总体处于上升趋势，我国、美国、英国、加拿大是该研究的主力军，学者们在疾病领域、保健衰老、美容养颜方面对干细胞神经元修复均开展了研究，主要集中在疾病、治疗方法、分子机制研究领域及相关细胞4个领域，共被引文献的研究主要围绕脊髓损伤、细胞治疗、神经再生等方面。
Abstract:
Objective To summarize the research status and development trend of stem cell neuron repair at home and abroad, and to provide reference for subsequent research in this field.Methods The 2729 papers in the Web of Science database with the subject term of stem cell neural repair* and the time range of 2012 to 2021 were taken as the research object. CiteSpace software was used to visually analyze the distribution of publication years and keyword emergence of stem cell neural repair research by bibliometric method.Results The annual distribution of the number of papers published in the literature mainly presents four stages, with an overall upward trend; the number of papers published in Asia, the Americas and Europe is the largest. Among them, there were 1070 papers published in Asia represented by China, accounting for 34.30% of the papers published. High frequency keywords for stem cell neuron repair were "neural stem cell" "stem cell", etc. A total of 22 clusters were formed in the clustering network, such as axonal regeneration, Parkinsons disease and so on. The emergence intensity of "central nervous system" was the highest. Studies in the fields of axonal regeneration, Parkinsons disease, and cell differentiation had taken a long time. The most cited literature was "Cell transplantation therapy for spinal cord injury", with a total citation frequency of 57 times.Conclusion Research related to stem cell neuronal repair is generally on the rise, with China, the United States, the United Kingdom, and Canada being the mainstays of this research. Scholars have conducted research on stem cell neuronal repair in the areas of disease, health care aging, and beauty care, mainly focusing on four areas of disease, therapeutic approaches, molecular mechanism research areas, and related cells, with studies in the total cited literature mainly centering on spinal cord injury, cell therapy, and nerve regeneration.

参考文献/References:

[1]任安艳,葛汝丽,王洪财.基因修饰的神经干细胞与帕金森病[J].国际神经病学神经外科学杂志,2022,49(1):68-72. [2]杨雨,刘定坤,李凌峰,等.Leptin转染人胎盘间充质干细胞对辐照后口腔黏膜修复细胞的作用及机制分析[J].中国实验诊断学,2021,25(12):1825-1830.[3]丁林宝,王珺,高志欣.社区中医药结合体质辨识防治痛风[J].上海医药,2018,39(12):22-23,56.[4]曹静,李梦佳,王芳,等.食蟹猴多功能干细胞向运动神经元定向分化[J].中国细胞生物学学报,2019,41(10):1976-1985.[5]张赛男,张丽,卢丹.脐带血干细胞向子宫内膜细胞分化的体外实验[J].国际医药卫生导报,2019,25(15):2467-2469.[6]高飞,蔡军,杨新春.体外定向诱导人工诱导多功能干细胞向心肌细胞分化[J].心血管病学进展,2012,33(2):179-181.[7]宫东伟,邢贻雷,王开琼,等.慢病毒介导Ras-GRF1调控肝癌干细胞干性维持与自我更新能力的机制[J].现代肿瘤医学,2022,30(17):3076-3082.[8]廖伟,蔡崇明,陈金明,等.miR-200b-Notch信号通路对诱导性多能干细胞向神经干细胞分化的调控作用[J].医学信息,2020,33(16):65-67.[9]李少婷,黄永增,蔡晓珍,等.胚胎干细胞临床试验中的伦理学问题及对策分析[J].中国医学伦理学,2018,31(9):1162-1165.[10]宋祖荣,陈涛.维A酸通过上调脑源性神经营养因子促进小鼠胚胎干细胞向神经细胞分化的研究[J].中国临床药理学杂志,2022,38(6):491-494.[11]Shi Y,Su J,Roberts AI,et al.How mesenchymal stem cells interact with tissue immune responses[J].Trends Immunol,2012,33(3):136-143.[12]Takahashi K,Yamanaka S.Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors[J].Cell,2006,126(4):663-676. [13]郭丹丹,李琳,吕莉娜,等.肥大细胞和干细胞因子在糖尿病肾病患者肾组织中的浸润表达及其意义[J].中国中西医结合肾病杂志,2021,22(8):682-686.[14]李晓寅,杨晓青,陈淑莲,等.胶原/丝素蛋白支架联合神经干细胞治疗创伤性脊髓损伤[J].中国组织工程研究,2023,27(6):890-896.[15]Ahmadian-Moghadam H,Sadat-Shirazi MS,Zarrindast MR.Therapeutic potential of stem cells for treatment of neurodegenerative diseases[J].Biotechnol Lett,2020,42(7):1073-1101.[16]孙田静,刘思佳,谢方可,等.干细胞来源外泌体在创伤性脑损伤修复中的作用与热点[J].中国组织工程研究,2021,25(1):123-127.[17]王震,张香路,李阳,等.改良透明质酸水凝胶控释脑源性神经营养因子对大鼠胚胎神经干细胞生长、分化和凋亡的影响[J].安徽医科大学学报,2022,57(5):805-811.[18]路晓淼,田瑞雪,刘姗姗,等.神经生长因子联合牙髓干细胞可促进大鼠种植体周围骨结合[J].南方医科大学学报,2021,41(9):1304-1309.[19]Ebrahimi T,Abasi M,Seifar F,et al.Transplantation of Stem Cells as a Potential Therapeutic Strategy in Neurodegenerative Disorders[J].Curr Stem Cell Res Ther,2021,16(2):133-144.

相似文献/References:

[1]李振宏.锌离子螯合剂对抗NMDA受体脑炎致海马神经元损伤的保护作用[J].医学信息,2020,33(08):92.[doi:10.3969/j.issn.1006-1959.2020.08.029]
　LI Zhen-hong.Protective Effect of Zinc Ion Chelator Against NMDA Receptor Encephalitis-induced Damage to Hippocampal Neurons[J].Journal of Medical Information,2020,33(13):92.[doi:10.3969/j.issn.1006-1959.2020.08.029]
[2]陶广林,马善新,廖 媚.A型肉毒毒素应用于神经性疼痛的研究[J].医学信息,2020,33(09):24.[doi:10.3969/j.issn.1006-1959.2020.09.009]
　TAO Guang-lin,MA Shan-xin,LIAO Mei.Study on the Application of Botulinum Toxin A in Neuropathic Pain[J].Journal of Medical Information,2020,33(13):24.[doi:10.3969/j.issn.1006-1959.2020.09.009]
[3]岳宇娇,徐 平.新生大鼠海马神经元原代细胞培养方法改良及鉴定[J].医学信息,2023,36(17):111.[doi:10.3969/j.issn.1006-1959.2023.17.021]
　YUE Yu-jiao,XU Ping.Improvement and Identification of Primary Cell Culture Method of Neonatal Rat Hippocampal Neurons[J].Journal of Medical Information,2023,36(13):111.[doi:10.3969/j.issn.1006-1959.2023.17.021]

更新日期/Last Update: 1900-01-01