[1]顾思嘉.眼底激光联合羟苯磺酸钙治疗Ⅲ~Ⅳ期糖尿病视网膜病变患者的临床效果分析[J].医学信息,2023,36(13):147-150.[doi:10.3969/j.issn.1006-1959.2023.13.032]
　GU Si-jia.Clinical Effect Analysis of Fundus Laser Combined with Calcium Dobesilate in the Treatment of Patients with Stage Ⅲ-Ⅳ Diabetic Retinopathy[J].Journal of Medical Information,2023,36(13):147-150.[doi:10.3969/j.issn.1006-1959.2023.13.032]
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眼底激光联合羟苯磺酸钙治疗Ⅲ~Ⅳ期糖尿病视网膜病变患者的临床效果分析()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
36卷
期数:
2023年13期
页码:
147-150
栏目:
论著
出版日期:
2023-07-01

文章信息/Info

Title:
Clinical Effect Analysis of Fundus Laser Combined with Calcium Dobesilate in the Treatment of Patients with Stage Ⅲ-Ⅳ Diabetic Retinopathy
文章编号:
1006-1959（2023）13-0147-04
作者:
顾思嘉
（启东市人民医院眼科，江苏 启东 226200）
Author(s):
GU Si-jia
(Department of Ophthalmology,Qidong People’s Hospital,Qidong 226200,Jiangsu,China)
关键词:
眼底激光; 羟苯磺酸钙; 糖尿病视网膜病变
Keywords:
Fundus laser; Calcium dobesilate; Diabetic retinopathy
分类号:
R587.2；R779.63
DOI:
10.3969/j.issn.1006-1959.2023.13.032
文献标志码:
A
摘要:
目的 探讨眼底激光联合羟苯磺酸钙治疗Ⅲ~Ⅳ期糖尿病视网膜病变患者的临床效果。方法 选取2021年1月-2022年1月在我院诊治的150例Ⅲ~Ⅳ期糖尿病视网膜病变患者为研究对象，采用随机数字表法分为对照组和观察组，各75例。对照组采用眼底激光治疗，观察组在对照组基础上联合应用羟苯磺酸钙治疗，比较两组临床疗效、临床症状（渗出吸收、视网膜水肿改善、眼底出血吸收）时间、黄斑厚度、血小板最大聚集率（MAR）、视力以及临床不良反应发生情况。结果 观察组治疗总有效率为93.33%，高于对照组的80.00%（P＜0.05）；观察组渗出吸收、视网膜水肿改善、眼底出血吸收时间均小于对照组（P＜0.05）；观察组黄斑厚度、MAR均小于对照组（P＜0.05）；观察组＞1.0视力人数占比高于对照组，0.7~1.0视力人数占比小于对照组（P＜0.05），0.4~0.6、≤0.4视力人数占比与对照组比较，差异无统计学意义（P＞0.05）；观察组不良反应发生率为4.00%，与对照组的5.33%比较，差异无统计学意义（P＞0.05）。结论 眼底激光联合羟苯磺酸钙治疗Ⅲ~Ⅳ期糖尿病视网膜病变效果确切，可提高治疗总有效率，促进渗出、水肿、出血改善，缩短临床症状改善时间。同时减小黄斑厚度，促进患者视力恢复，且不会增加不良反应，是一种安全、可行的治疗方案。
Abstract:
Objective To investigate the clinical effect of fundus laser combined with calcium dobesilate in the treatment of patients with stage Ⅲ-Ⅳ diabetic retinopathy.Methods A total of 150 patients with stage Ⅲ-Ⅳ diabetic retinopathy diagnosed and treated in our hospital from January 2021 to January 2022 were selected as the research objects. They were divided into control group and observation group by random number table method, with 75 patients in each group. The control group was treated with fundus laser, and the observation group was treated with calcium dobesilate on the basis of the control group. The clinical efficacy, clinical symptoms (exudation absorption, retinal edema improvement, fundus hemorrhage absorption) time, macular thickness, maximum platelet aggregation rate (MAR), visual acuity and clinical adverse reactions were compared between the two groups.Results The total effective rate of treatment in the observation group was 93.33%, which was higher than 80.00% in the control group (P＜0.05). The time of exudation absorption, retinal edema improvement and fundus hemorrhage absorption in the observation group were less than those in the control group (P＜0.05). The macular thickness and MAR in the observation group were lower than those in the control group (P＜0.05). The proportion of people with visual acuity ＞1.0 in the observation group was higher than that in the control group, and the proportion of people with visual acuity of 0.7-1.0 was lower than that in the control group (P＜0.05), while there was no significant difference in the proportion of patients with visual acuity of 0.4-0.6 and ≤0.4 between the observation group and the control group (P＞0.05). The incidence of adverse reactions in the observation group was 4.00%, which was compared with 5.33% in the control group, the difference was not statistically significant (P＞0.05). Conclusion Fundus laser combined with calcium dobesilate is effective in the treatment of stage Ⅲ-Ⅳ diabetic retinopathy, which can improve the total effective rate of treatment, promote the improvement of exudation, edema and hemorrhage, and shorten the improvement time of clinical symptoms. At the same time, it can reduce macular thickness and promote visual acuity recovery without increase adverse reactions, thus it is a safe and feasible treatment.

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更新日期/Last Update: 1900-01-01