[1]王 锐.有创机械通气序贯高流量湿化治疗在重症肺炎并呼吸衰竭中的应用价值[J].医学信息,2023,36(21):82-85.[doi:10.3969/j.issn.1006-1959.2023.21.018]
　WANG Rui.Application Value of Invasive Mechanical Ventilation and Sequential High Flow Humidification Therapy in Severe Pneumonia Complicated with Respiratory Failure[J].Journal of Medical Information,2023,36(21):82-85.[doi:10.3969/j.issn.1006-1959.2023.21.018]
点击复制

有创机械通气序贯高流量湿化治疗在重症肺炎并呼吸衰竭中的应用价值()
分享到：

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
36卷
期数:
2023年21期
页码:
82-85
栏目:
论著
出版日期:
2023-11-01

文章信息/Info

Title:
Application Value of Invasive Mechanical Ventilation and Sequential High Flow Humidification Therapy in Severe Pneumonia Complicated with Respiratory Failure
文章编号:
1006-1959（2023）21-0082-04
作者:
王 锐
（弋阳县人民医院重症医学科，江西 弋阳 334400）
Author(s):
WANG Rui
(Department of Critical Care Medicine,Yiyang County People’s Hospital,Yiyang 334400,Jiangxi,China)
关键词:
有创机械通气; 高流量湿化治疗; 重症肺炎; 呼吸衰竭
Keywords:
Invasive mechanical ventilation; High flow humidification therapy; Severe pneumonia; Respiratory failure
分类号:
R563.1；R563.8
DOI:
10.3969/j.issn.1006-1959.2023.21.018
文献标志码:
A
摘要:
目的 研究有创机械通气序贯高流量湿化治疗在重症肺炎并呼吸衰竭治疗中的应用价值。方法 选取2019年5月-2022年5月在我院诊治的80例重症肺炎并呼吸衰竭患者为研究对象，采用随机数字表法分为对照组（n=40）和观察组（n=40），对照组采用常规有创机械通气治疗，观察组采用有创机械通气序贯高流量湿化治疗。比较两组临床疗效、机械通气时间、ICU入住时间、血气指标[动脉血氧分压（PaO2）、动脉血二氧化碳分压（PaCO2）]、急性生理与慢性健康状况评分（APACHEⅡ）及并发症发生率。结果 观察组治疗总有效率（95.00%）高于对照组（82.50%）（P＜0.05）；观察组机械通气时间、ICU入住时间短于对照组（P＜0.05）；观察组治疗后PaO2大于对照组，PaCO2小于对照组（P＜0.05）；两组治疗后APACHEⅡ评分均低于治疗前，且观察组低于对照组（P＜0.05）；观察组并发症发生率为7.50%，低于对照组的20.00%（P＜0.05）。结论 采用有创机械通气序贯高流量湿化治疗重症肺炎并呼吸衰竭可有效改善患者血气指标，促进自主呼吸恢复，缩短机械通气和ICU入住时间，有效控制病情进展，且可降低并发症发生率。
Abstract:
Objective To study the application value of invasive mechanical ventilation and sequential high flow humidification therapy in severe pneumonia complicated with respiratory failure.Methods A total of 80 patients with severe pneumonia and respiratory failure diagnosed and treated in our hospital from May 2019 to May 2022 were selected as the research objects. They were divided into control group (n=40) and observation group (n=40) by random number table method. The control group was treated with conventional invasive mechanical ventilation, and the observation group was treated with invasive mechanical ventilation and sequential high flow humidification therapy. The clinical efficacy, mechanical ventilation time, ICU stay time, blood gas indexes [arterial partial pressure of oxygen (PaO2), arterial partial pressure of carbon dioxide (PaCO2)], acute physiology and chronic health status score (APACHEⅡ) and complication rate were compared between the two groups.Results The total effective rate of treatment in the observation group (95.00%) was higher than that in the control group (82.50%) (P<0.05). The mechanical ventilation time and ICU stay time in the observation group were shorter than those in the control group (P<0.05). After treatment, PaO2 in the observation group was higher than that in the control group, and PaCO2 was lower than that in the control group (P<0.05). The APACHE II scores of the two groups after treatment were lower than those before treatment, and the observation group was lower than the control group (P<0.05). The incidence of complications in the observation group was 7.50%, which was lower than 20.00% in the control group (P<0.05).Conclusion Invasive mechanical ventilation and sequential high flow humidification in the treatment of severe pneumonia and respiratory failure can effectively improve the blood gas index, promote the recovery of spontaneous breathing, shorten the time of mechanical ventilation and ICU stay, effectively control the progress of the disease, and reduce the incidence of complications.

参考文献/References:

[1]冯晓丽,黄娜,李培培,等.无创序贯机械通气对重症肺炎合并呼吸衰竭患者血浆ANP、NT-proBNP的影响 [J]. 西部医学,2018,30(5):724-727.[2]王开成,辛宝琼,张冠军,等.支气管镜肺泡灌洗联合无创通气治疗重症肺炎合并呼吸衰竭的疗效观察 [J].广西医科大学学报,2018,35(1):68-71.[3]林建良,郑辉才.无创正压机械通气辅助治疗重症肺炎合并呼吸衰竭效果分析[J].医学综述,2016,22(3):606-608.[4]Fanfulla F,Taurino AE,Lupo ND,et al.Effect of sleep on patient ventilator asynchrony in patients undergoing chronic non-invasive mechanical ventilation[J].Respiratory Medicine,2017,101(8):1702-1707.[5]李蕾,闫登峰.有创-无创序贯机械通气在重症肺炎治疗中的应用 [J].江苏医药,2016,42(4):464-465.[6]易琳琳,余秀,叶云,等.清金化痰汤与盐酸氨溴索联合无创机械通气治疗老年慢性阻塞性肺疾病合并重症呼吸衰竭的临床研究 [J].中国中医急症,2018,27(2):226-229.[7]中华医学会呼吸病学分会感染学组. 中国成人医院获得性肺炎与呼吸机相关性肺炎诊断和治疗指南(2018 年版)[J].中华结核和呼吸杂志,2018,41(4):255-280.[8]卞乐乐.呼吸衰竭患儿机械通气治疗中的应用效果及其并发症发生情况分析[J].中国妇幼保健,2019,34(9):2024-2027.[9]鲍倩,王金荣,杜雅楠,等.尼可刹米注射液联合有创无创序贯机械通气治疗慢性阻塞性肺疾病合并严重呼吸衰竭效果观察[J].解放军医药杂志,2022,34(1):72-76.[10]颜春悦,叶晓东,苏长就.有创-无创序贯性机械通气对老年重症肺炎患者预后的影响[J].哈尔滨医药,2017,36(2):103-104.[11]王敬敏,刘冬梅,徐琳,等.血浆NT-proBNP及H-FABP联合检测在小儿重症肺炎合并心力衰竭中的应用价值[J].解放军医药杂志,2017,29(9):106-109.[12]孟永胜,何宏蕴,石宏.动态无创肺动脉压力在重症肺炎伴呼吸衰竭监测中的应用分析[J].重庆医学,2017,45(23):3273-3275．[13]Mathieu B,Laure-Anne P,Irene D,et al.Mechanical ventila tion and streptococcus pneumoniae pneumonia alter mitochondrial homeostasis[J].Sci Reports,2018,8(1):11718-11731.[14]梁振明,辜德明,陈运旺,等.有创机械通气重症肺炎患儿感染闭塞性毛细支气管炎影响因素分析[J].中华医院感染学杂志,2019,29(3):137-139,143.[15]石买雄.有创-无创序贯机械通气在 95 例重症肺炎合并呼吸衰竭治疗中的效果观察[J].贵州医药,2019,43(11):1718-1720.[16]龙继贤,高文妹.有创-无创序贯机械通气治疗慢性阻塞性肺疾病所致急性呼吸衰竭的疗效[J].临床内科杂志,2018,35(3):181-183.[17]王春亚,赵玉杰,王小闯,等.有创无创序贯通气对急性呼吸衰竭患者血糖水平及预后的影响[J].现代生物医学进展,2019,19(8):1490-149 [18]王洪武,黄琳惠,蔡兴俊,等.有创-无创序贯机械通气治疗AECOPD合并Ⅱ型呼吸衰竭患者的临床疗效及影响因素[J].山东医药,2020,60(13):79-82.[19]喻廷凤.有创机械通气序贯高流量湿化氧疗在重症肺炎并呼吸衰竭治疗中的应用价值[J].实用医技杂志,2021,28(5):646-648.[20]黄艳辉.有创-无创序贯机械通气治疗 ICU 重症肺炎合并呼吸衰竭的效果观察[J].甘肃医药,2022,41(6):517-520.

相似文献/References:

[1]唐艺菡,刘艳宾,邹 敏,等.加温加湿经鼻导管高流量氧疗的研究[J].医学信息,2019,32(15):48.[doi:10.3969/j.issn.1006-1959.2019.15.016]
　TANG Yi-han,LIU Yan-bin,ZOU Min,et al.Study on Warming and Humidifying Nasal Catheter with High Flow Oxygen Therapy[J].Journal of Medical Information,2019,32(21):48.[doi:10.3969/j.issn.1006-1959.2019.15.016]
[2]孙晓岩.有创机械通气治疗COPD患者呼吸衰竭的效果观察[J].医学信息,2020,33(05):104.[doi:10.3969/j.issn.1006-1959.2020.05.032]
　SUN Xiao-yan.Observation on the Effect of Invasive Mechanical Ventilation on Respiratory Failure in Patients with Chronic Obstructive Pulmonary Disease[J].Journal of Medical Information,2020,33(21):104.[doi:10.3969/j.issn.1006-1959.2020.05.032]

更新日期/Last Update: 1900-01-01