[1]肖秋秋.宫腔镜下子宫内膜息肉电切术后口服孕激素与曼月乐环对复发的预防作用[J].医学信息,2023,36(24):98-101.[doi:10.3969/j.issn.1006-1959.2023.24.021]
　XIAO Qiu-qiu.Preventive Effect of Oral Progesterone and Mirena Ring on Recurrence After Hysteroscopic Endometrial Polypectomy[J].Journal of Medical Information,2023,36(24):98-101.[doi:10.3969/j.issn.1006-1959.2023.24.021]
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宫腔镜下子宫内膜息肉电切术后口服孕激素与曼月乐环对复发的预防作用()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
36卷
期数:
2023年24期
页码:
98-101
栏目:
论著
出版日期:
2023-12-15

文章信息/Info

Title:
Preventive Effect of Oral Progesterone and Mirena Ring on Recurrence After Hysteroscopic Endometrial Polypectomy
文章编号:
1006-1959（2023）24-0098-04
作者:
肖秋秋
（余干楚东医院妇产科，江西 余干 335100）
Author(s):
XIAO Qiu-qiu
(Department of Obstetrics and Gynecology,Yugan Chudong Hospital,Yugan 335100,Jiangxi,China)
关键词:
宫腔镜子宫内膜息肉电切术; 孕激素; 曼月乐环; 复发率
Keywords:
Hysteroscopic endometrial polypectomy; Progesterone; Mirena ring; Recurrence rate
分类号:
R713.4
DOI:
10.3969/j.issn.1006-1959.2023.24.021
文献标志码:
A
摘要:
目的 研究宫腔镜下子宫内膜息肉电切术后口服孕激素与曼月乐环对复发的预防作用。方法 选取2021年5月-2022年2月我院行宫腔镜下子宫内膜息肉电切术的68例患者为研究对象，采用随机数字表法分为观察组和对照组，每组34例。对照组术后口服孕激素，观察组术后采用曼月乐环放置治疗，比较两组复发率、月经指标、子宫内膜厚度、性激素水平[卵泡雌激素（FSH）、促黄体生成素（LH）、雌二醇（E2）]以及不良反应发生情况。结果 随访6个月，观察组复发率为2.94%，低于对照组的14.71%（P＜0.05）；观察组治疗2个月后月经量、月经周期均小于对照组（P＜0.05）；两组治疗后2、3、6个月子宫内膜厚度均小于治疗前，且观察组小于对照组（P＜0.05）；两组治疗前后FSH、LH、E2水平比较，差异无统计学意义（P＞0.05）；观察组不良反应发生率为5.88%，低于对照组的17.65%（P＜0.05）。结论 宫腔镜下子宫内膜息肉电切术后给予口服孕激素与曼月乐环放置均可发挥一定的预防作用，但曼月乐环放置治疗可降低复发率、不良反应发生率，促进子宫内膜厚度缩小，抑制性激素水平下降，改善月经量和周期，利于患者的良好预后，具有重要的临床应用价值。
Abstract:
Objective To study the preventive effect of oral progesterone and Mirena ring on recurrence after hysteroscopic endometrial polypectomy.Methods A total of 68 patients who underwent hysteroscopic endometrial polypectomy in our hospital from May 2021 to February 2022 were selected as the research objects. They were divided into observation group and control group by random number table method, with 34 patients in each group. The control group was treated with oral progesterone after operation, and the observation group was treated with Mirena ring placement after operation. The recurrence rate, menstrual index, endometrial thickness, sex hormone levels [follicle estrogen (FSH), luteinizing hormone (LH), estradiol (E2)] and adverse reactions were compared between the two groups.Results After 6 months of follow-up, the recurrence rate of the observation group was 2.94%, which was lower than 14.71% of the control group (P<0.05). The menstrual volume and menstrual cycle of the observation group were less than those of the control group after 2 months of treatment (P<0.05). The endometrial thickness of the two groups at 2, 3 and 6 months after treatment was less than that before treatment, and that of the observation group was less than that of the control group (P<0.05). There was no significant difference in the levels of FSH, LH and E2 between the two groups before and after treatment (P>0.05). The incidence of adverse reactions in the observation group was 5.88%, which was lower than 17.65% in the control group (P<0.05).Conclusion Oral progesterone and Mirena ring can play a certain role in preventing recurrence after hysteroscopic endometrial polypectomy. However, Mirena ring can reduce the recurrence rate and the incidence of adverse reactions, promote the reduction of endometrial thickness, inhibit the decrease of sex hormone levels, improve menstrual volume and cycle, and benefit the good prognosis of patients, which has important clinical application value.

参考文献/References:

[1]陈淳渊,叶飞雪.宫腔镜下行电切术结合刮宫术对多发性子宫内膜息肉患者免疫功能的影响[J].医学理论与实践,2020,33(10):1648-1650.[2]豆晓蕾.去氧孕烯炔雌醇片联合宫腔镜手术对多发性子宫内膜息肉的效果[J].河南医学研究,2020,29(10):1773-1774.[3]聂立新,刘丽丽.宫腔负压吸刮术联合宫腔镜电切术治疗不孕症多发性子宫内膜息肉的临床研究[J].临床医学,2019,39(12):34-35.[4]余平芝,李菲菲.子宫内膜息肉行宫腔镜联合天然孕激素治疗的效果观察[J].中华全科医学,2022,20(2):267-269.

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更新日期/Last Update: 1900-01-01