[1]廖加群,曹 雪,陈燕平,等.宫颈癌盆腔淋巴结转移分布及危险因素分析[J].医学信息,2018,31(03):25-27.[doi:10.3969/j.issn.1006-1959.2018.03.008]
 LIAO Jia-qun,CAO Xue,CHEN Yan-ping,et al.Distribution and Risk Factors of Pelvic Lymph Node Metastasis in Cervical Cancer[J].Medical Information,2018,31(03):25-27.[doi:10.3969/j.issn.1006-1959.2018.03.008]
点击复制

宫颈癌盆腔淋巴结转移分布及危险因素分析()

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
31卷
期数:
2018年03期
页码:
25-27
栏目:
出版日期:
2018-02-01

文章信息/Info

Title:
Distribution and Risk Factors of Pelvic Lymph Node Metastasis in Cervical Cancer
文章编号:
1006-1959(2018)03-0025-03
作者:
廖加群曹 雪陈燕平吴 莉鲁 亮刘云聪李 杭杨飞月
贵州省人民医院肿瘤科,贵州 贵阳 550002
Author(s):
LIAO Jia-qunCAO XueCHEN Yan-pingWU LiLU LiangLIU Yun-congLI HangYANG Fei-yue
Department of Oncology,Guizhou Provincial People’s Hospital,Guiyang 550002,Guizhou,China
关键词:
宫颈癌淋巴结转移危险因素
Keywords:
Cervical cancerLymph node metastasisRisk factors
分类号:
R737.3
DOI:
10.3969/j.issn.1006-1959.2018.03.008
文献标志码:
A
摘要:
目的 分析贵州地区宫颈癌淋巴结转移的临床病理特点。方法 收集2010年2月~2014年7月我院收治的ⅠB~ⅡB期168例宫颈癌手术患者临床病理资料,回顾性分析淋巴结分布情况及相关高危因素及预后。结果 淋巴结转移部位差异有统计学意义(P<0.05),闭孔淋巴结最易出现转移,淋巴结转移与FIGO分期、脉管癌栓/神经侵犯、宫旁浸润、病理分化程度、肌层浸润深度均有关,与病理类型及年龄无关。淋巴结转移组预后较非转移组差。结论 宫颈癌淋巴结分布以顺站转移为主,分期、脉管癌栓/神经侵犯、宫旁浸润、病理分化程度、肌层浸润深度是淋巴结转移危险因素,淋巴结转移者预后差于无转移者。
Abstract:
Objective To analyze the clinicopathological features of cervical lymph node metastasis in Guizhou province.Methods The clinical and pathological data of 168 patients with stage ⅠB~ⅡB cervical cancer admitted to our hospital from February 2010 to July 2014 were retrospectively analyzed.The distribution of lymph nodes and related risk factors and prognosis were retrospectively analyzed.Results There were significant differences in lymph node metastasis between the two groups(P<0.05).Most of the closed-cell lymph node metastases,lymph node metastasis and FIGO staging,vascular tumor thrombosis/nerve invasion,uterine infiltration, pathological differentiation,depth of myometrial invasion related.Has nothing to do with the pathological type and age.The prognosis of lymph node metastasis group was worse than that of non-metastasis group.Conclusion The distribution of lymph nodes in cervical cancer was mainly in the same station,stage,vascular tumor embolus/nerve invasion,periuterine infiltration,pathological differentiation, depth of myometrium invasion were risk factors of lymph node metastasis.The prognosis of lymph node metastasis was worse than that of non-metastasis.

参考文献/References:

[1]蒋艳萍,曹来英,洛若愚.Treg细胞和IDO在HPV感染相关宫颈疾病组织中表达及意义[J].实用癌症杂志,2012,27(1):32-35.
[2]Sakuragi N,Satoh C,Takeda N,et al.Incidence and distribution pattern of pelvic and paraortic lymph node metastasis in patients with Stage ⅠB,ⅡA,and ⅡB cervical carcinoma treated with hys-terectomy[J].Cancer,1999,85(7):1547-1554.
[3]Peters WR,Liu PY,Barrett RJ,et al.Concurrent chemotherapy and pelvic radiation therapy compared with pelvic radiation therapy alone as adjuvant therapy after radical surgery in high-risk early-stage cancer of the cervix[J].J Clin Oncol,2000,18(8):1606-1613.
[4]蒋乐萍.宫颈癌患者淋巴结转移的影响因素分析[J].实用癌症杂志,2013,28(6):731-733.
[5]Rutledge TL,Kamelle SA,Tollmanns TD,et al.A comparison of stage IB1 and IB2 cerical cancers treadted with radical hysterectomy.Is size the difference[J].Gynecol Oncol,2004,95(1):70-76.
[7]Dos-Reis R,Frumovitz M,Milam MR,et a1.Adenosquamous carcinoma versus adenocarcinoma in early stage cervical cancer patients undergoing radical hysterectomy:an outcomes analysis[J].Gynecol Oncol,2007,107(3):458-463.
[8]Farley JH,Hiekey KW,Carlson JW,et a1.Adenosquamous histology predicts a poor outcome for patients with advanced-stage,but not early-stage,cervical carcinoma[J].Cancer,2003,97(9):2196-2202.
[9]Wang S S,Sherman M E,Silverberg S G,et al.Pathological characteristics of cervical adenocarcinoma in a multi-center U.S.-based study[J].Gynecologic Oncology,2006,103(2):541-546.
[10]Ryu S Y,Kim M H,Nam B H,et al.Intermediate-risk grouping of cervical cancer patients treated with radical hysterectomy:a Korean Gynecologic Oncology Group study[J].British Journal of Cancer,2014,110(2):278-285.

相似文献/References:

[1]徐 洁.宫颈癌筛查及预防的研究进展[J].医学信息,2018,31(09):70.[doi:10.3969/j.issn.1006-1959.2018.09.022]
 XU Jie.Advances in Screening and Prevention of Cervical Cancer[J].Medical Information,2018,31(03):70.[doi:10.3969/j.issn.1006-1959.2018.09.022]
[2]蔡亚磊,邓思雨,杨 健.宫颈癌放疗增敏的研究现状[J].医学信息,2022,35(09):65.[doi:10.3969/j.issn.1006-1959.2022.09.016]
 CAI Ya-lei,DENG Si-yu,YANG Jian.Research Status of Radiotherapy Sensitization for Cervical Cancer[J].Medical Information,2022,35(03):65.[doi:10.3969/j.issn.1006-1959.2022.09.016]
[3]车 莹.HPV感染与宫颈病变相关性的研究[J].医学信息,2022,35(09):84.[doi:10.3969/j.issn.1006-1959.2022.09.021]
 CHE Ying.Study on the Correlation Between HPV Infection and Cervical Lesions[J].Medical Information,2022,35(03):84.[doi:10.3969/j.issn.1006-1959.2022.09.021]
[4]曹 亮,郝 朋,李阳明,等.宫颈癌所致输尿管梗阻患者输尿管支架置入成功率影响因素的Meta分析[J].医学信息,2022,35(09):124.[doi:10.3969/j.issn.1006-1959.2022.09.031]
 CAO Liang,HAO Peng,LI Yang-ming,et al.Meta Analysis of Factors Influencing Success Rate of Ureteral Stent Implantation in Patients with Ureteral Obstruction Caused by Cervical Cancer[J].Medical Information,2022,35(03):124.[doi:10.3969/j.issn.1006-1959.2022.09.031]
[5]覃念群,刘 楷,米镜霖,等.基于生物信息学分析筛选与宫颈癌预后相关的关键基因[J].医学信息,2022,35(10):8.[doi:10.3969/j.issn.1006-1959.2022.10.002]
 QIN Nian-qun,LIU Kai,MI Jing-lin,et al.Screening Key Genes Related to the Prognosis of Cervical Cancer Based on Bioinformatics Analysis[J].Medical Information,2022,35(03):8.[doi:10.3969/j.issn.1006-1959.2022.10.002]
[6]黄 花,徐冬冬,章丽霞.TGF-β1在宫颈癌中的研究进展[J].医学信息,2018,31(12):31.[doi:10.3969/j.issn.1006-1959.2018.12.011]
 HUANG Hua,XU Dong-dong,ZHANG Li-xia.Research Progress of TGF-β1 in Cervical Cancer[J].Medical Information,2018,31(03):31.[doi:10.3969/j.issn.1006-1959.2018.12.011]
[7]夏易曼娜,李虎成.腹腔镜下宫颈癌根治术与传统开腹手术的对比研究[J].医学信息,2018,31(12):115.[doi:10.3969/j.issn.1006-1959.2018.12.036]
 XIA Yi-manna,LI Hu-cheng.Comparative Study of Laparoscopic Radical Resection of Cervical Cancer and Traditional Open Surgery[J].Medical Information,2018,31(03):115.[doi:10.3969/j.issn.1006-1959.2018.12.036]
[8]杨 军,王翠平,李 龙,等.义安区体检HPV-DNA筛查结果分析[J].医学信息,2018,31(14):136.[doi:10.3969/j.issn.1006-1959.2018.14.041]
 YANG Jun,WANG Cui-ping,LI Long,et al.Analysis of the Results of HPV-DNA Screening in the Medical Examination of Yian District[J].Medical Information,2018,31(03):136.[doi:10.3969/j.issn.1006-1959.2018.14.041]
[9]王双英,张 娜,刘 芳.具有高危复发因素的早期宫颈癌术后辅助治疗进展[J].医学信息,2018,31(15):33.[doi:10.3969/j.issn.1006-1959.2018.15.012]
 WANG Shuang-ying,ZHANG Na,LIU Fang.Advances in Postoperative Adjuvant Therapy for Early Cervical Cancer with High Risk of Recurrence[J].Medical Information,2018,31(03):33.[doi:10.3969/j.issn.1006-1959.2018.15.012]
[10]聂小凤,翟慧慧,冷天艳,等.宫颈脱落细胞miR34a检测在HR-HPV阳性患者 分流中的作用分析[J].医学信息,2018,31(16):43.[doi:10.3969/j.issn.1006-1959.2018.16.012]
 NIE Xiao-feng,ZHAI Hui-hui,LENG Tian-yan,et al.Analysis of the Role of MiR34a in Cervical Exfoliated Cells in Shunt of HR-HPV Positive Patients[J].Medical Information,2018,31(03):43.[doi:10.3969/j.issn.1006-1959.2018.16.012]
[11]邵景萍.早期宫颈癌术后预后影响因素研究[J].医学信息,2022,35(13):66.[doi:10.3969/j.issn.1006-1959.2022.13.014]
 SHAO Jing-ping.Study on Prognostic Factors of Early Cervical Cancer After Operation[J].Medical Information,2022,35(03):66.[doi:10.3969/j.issn.1006-1959.2022.13.014]

更新日期/Last Update: 2018-02-01