[1]赵雪梅,王利娜,王 啸,等.髌软骨T2 mapping与膝关节骨性关节炎临床症状间的 关系及影响因素[J].医学信息,2018,31(08):57-61.[doi:10.3969/j.issn.1006-1959.2018.08.018]
 ZHAO Xue-mei,WANG Li-na,WANG Xiao,et al.Relationship between T2 mapping of Patellar Cartilage and Clinical Symptoms of Osteoarthritis of Knee Joint and its Influencing Factors[J].Journal of Medical Information,2018,31(08):57-61.[doi:10.3969/j.issn.1006-1959.2018.08.018]
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髌软骨T2 mapping与膝关节骨性关节炎临床症状间的 关系及影响因素()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
31卷
期数:
2018年08期
页码:
57-61
栏目:
论著
出版日期:
2018-04-15

文章信息/Info

Title:
Relationship between T2 mapping of Patellar Cartilage and Clinical Symptoms of Osteoarthritis of Knee Joint and its Influencing Factors
文章编号:
1006-1959(2018)08-0057-05
作者:
赵雪梅王利娜王 啸钱银锋
安徽医科大学第一附属医院放射科,安徽 合肥 230000
Author(s):
ZHAO Xue-meiWANG Li-naWANG XiaoQIAN Yin-feng
Department of Radiology,First Affiliated Hospital of Anhui Medical University,Hefei 230000,Anhui,China
关键词:
膝关节骨性关节炎T2 mapping软骨缺损骨髓病变
Keywords:
Key words:Knee jointOsteoarthritisT2 mappingCartilage defectBone marrow lesion
分类号:
R684;R445.2
DOI:
10.3969/j.issn.1006-1959.2018.08.018
文献标志码:
A
摘要:
目的 探讨膝骨关节炎患者髌软骨T2 mapping与临床症状、关节软骨缺损及骨髓病变间的关系。方法 回顾性选取2017年1月~7月本院32例符合1986年美国风湿学会症状性膝关节骨性关节炎患者,行膝关节MRI检查,包括T2WI、3D FSPGR和T2 mapping,评估髌软骨缺损及骨髓病变分级,在T2 mapping图像上勾画ROI,测量髌软骨T2值,以T2值中位数为区分标准,作各项指标的两组间比较,Logistic回归分析骨髓病变、软骨缺损与T2值间的相关性,行方差分析观察软骨缺损及骨髓水肿与T2值间的关系。结果 软骨缺损及骨髓病变在两组间有统计学差异,P值均<0.05。Logistic回归分析发现软骨缺损及骨髓病变与T2值是否高于中位数相关,P值分别为0.003及0.032;不同等级关节软骨缺损及骨髓病变间T2值不同,且呈现增高趋势,P值均<0.05。结论 不同等级的软骨缺损及骨损伤具有不同的T2值,且随着等级的增高,T2值亦呈现增高趋势。
Abstract:
Abstract:Objective To investigate the relationship between T2 mapping of patellar cartilage and clinical symptoms,articular cartilage defects and bone marrow lesions in patients with knee osteoarthritis.Methods From January to July 2017,32 patients with symptomatic osteoarthritis of knee joint,who were in accordance with the 1986 American Rheumatology Society,were examined with MRI,including T2WI,3DFSPGR and T2 mapping.The patellar cartilage defects and bone marrow lesions were evaluated.To evaluate the grade of patellar cartilage defect and bone marrow lesion,draw ROI on T2 mapping image,measure T2 value of patellar cartilage,and use median T2 value as the distinguishing criterion.The relationship between bone marrow lesion,cartilage defect and T2 value was compared between the two groups.The relationship between cartilage defect,bone marrow edema and T2 value was observed by ANOVA.Results There was significant difference in cartilage defect and bone marrow lesion between the two groups,P values were all<0.05.Logistic regression analysis showed that the correlation between cartilage defect and bone marrow lesion and T2 P values were 0.003 and 0.032 respectively.Different grades of articular cartilage defects and bone marrow lesions showed different T2 values and showed an increasing trend.P values were all<0.05,respectively.Conclusion Different grades of cartilage defects and bone injuries have different T2 values,and with the increase of grade,T2 values also show an increasing trend.

参考文献/References:

[1]Wei W,Lambach B,Jia G,et al.A Phase I clinical trial of the knee to assess the correlation of gagCEST MRI,delayed gadolinium-enhanced MRI of cartilage and T2 mapping[J].Eur J Radiol,2017(90):220-224.
[2]Baum T,Joseph GB,Arulanandan A,et al.Association of magnetic resonance imaging-based knee cartilage T2 measurements and focal knee lesions with knee pain:date from the Osteoarthritis Initiative[J].Arthritis Res(Hoboken),2012,64(2):248-255.
[3]周北凡.我国成人体重指数和腰围对相关疾病危险因素异常的预测价值:适宜体重指数和腰围切点的研究[J].中华流行病学杂志,2002,23(1):5-10.
[4]Kapstad H,Hanestad BR,Langeland N,et al.Cutpoints for mild, moderate and severe pain in patients with osteoarthritis of the hip or knee ready for joint replacement surgery[J].BMC Musculoskelet Disord,2008(9):55.
[5]Kijowski R,Blankenbaker DG,Munoz Del Rio A,et al.Evaluation of the articular cartilage of the knee joint: value of adding a T2 mapping sequence to a routine MR imaging protocol[J].Radiology,2013,267(2):503-513.
[6]Peterfy CG,Guermazi A,Zaim S,et al.Whole-Organ Magnetic Resonance Imaging Score(WORMS)of the knee in osteoarthritis[J].Osteoarthritis Cartilage,2004,12(3):177-190.
[7]Hada S,Kaneko H,Sadatsuki R,et al.The degeneration and destruction of femoral articular cartilage shows a greater degree of deterioration than that of the tibial and patellar articular cartilage in early stage knee osteoarthritis:a cross-sectional study[J].Osteoarthritis Cartilage,2014,22(10):1583-1589.
[8]王平,黄刚,张文文,等.应用磁共振T2-mapping成像评价非专业马拉松运动员膝关节软骨改变[J].中国临床医学影像杂志,2014,25(12):877-881.
[9]Soellner ST,Goldmann A,Muelheims D,et al.Intraoperative validation of quantitative T2 mapping in patients with articular cartilage lesions of the knee[J].Osteoarthritis Cartilage,2017,25(11):1841-1849.
[10]方舒,邢伟.T2弛豫时间图在膝关节软骨下骨髓水肿与软骨损伤相关性研究中的应用[J].中国中西医结合影像学杂志,2015,13(4):367-369.
[11]Joseph GB,McCulloch CE,Nevitt MC,et al.A reference database of cartilage 3 T MRI T2 values in knees without diagnostic evidence of cartilage degeneration:data from the osteoarthritis initiative[J].Osteoarthritis Cartilage,2015,23(6):897-905.

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更新日期/Last Update: 2018-04-15