[1]邢 均.全身麻醉联合硬膜外麻醉在宫颈癌手术中的应用及效果评价[J].医学信息,2019,32(01):122-124,130.[doi:10.3969/j.issn.1006-1959.2019.01.037]
　XING Jun.Application and Evaluation of General Anesthesia Combined with Epidural Anesthesia in[J].Journal of Medical Information,2019,32(01):122-124,130.[doi:10.3969/j.issn.1006-1959.2019.01.037]
点击复制

全身麻醉联合硬膜外麻醉在宫颈癌手术中的应用及效果评价()
分享到：

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
32卷
期数:
2019年01期
页码:
122-124,130
栏目:
临床研究
出版日期:
2019-01-01

文章信息/Info

Title:
Application and Evaluation of General Anesthesia Combined with Epidural Anesthesia in
文章编号:
1006-1959（2019）01-0122-04
作者:
邢 均
湖北省丹江口市第一医院麻醉科，湖北 丹江口 442700
Author(s):
XING Jun
Department of Anesthesiology,the First Hospital of Danjiangkou City,Danjiangkou 442700, Hubei,China
关键词:
宫颈癌; 全麻; 硬膜外麻醉; 应激反应; 不良反应
Keywords:
Cervical cancer; General anesthesia; Epidural anesthesia; Stress response; Adverse reactions
分类号:
R614；R737.33
DOI:
10.3969/j.issn.1006-1959.2019.01.037
文献标志码:
A
摘要:
目的 分析全身麻醉联合硬膜外麻醉对宫颈癌手术患者的麻醉效果、应激反应及不良事件。方法 选取2015年7月~2017年7月在我院接受腹腔镜术治疗的84例宫颈癌患者临床资料，按照随机数表法分两组，每组42例。对照组行全麻，观察组行全麻+硬膜外麻醉，比较两组麻醉合格率、异氟醚用量、麻醉苏醒时间，麻醉诱导后、建立气腹后、术毕时的应激反应及不良事件发生。结果 观察组麻醉合格率为92.85%，高于对照组的71.43%，且观察组异氟醚的用量为（16.21±4.11）ml较对照组的（30.74±5.74）ml少，麻醉苏醒时间为（10.21±2.43）min较对照组的（16.91±1.74）min短，差异均有统计学意义（P＜0.05）；麻醉诱导后、建立气腹后、术毕时的观察组HR分别为（80.64±7.53） 次/min、（77.47±9.78） 次/min、（78.52±7.92）次/min低于对照组的（91.39±8.92）次/min、（94.69±7.80）次/min、（93.68±8.47）次/min；观察组SBP分别为（138.26±11.21） mmHg、（143.23±15.84） mmHg、（145.74±14.09）mmHg，低于对照组的（146.79±10.41） mmHg、（152.76±14.18） mmHg、（156.18±10.21）mmHg，DBP分别为（76.03±5.26） mmHg、（77.92±8.71） mmHg、（79.81±9.23）mmHg，低于对照组的（82.56±6.37） mmHg、（93.68±8.34） mmHg、（92.31±9.57） mmHg （P＜0.05）；观察组术后不良反应率（11.90%）低于对照组（30.95%）（P＜0.05）。结论 全麻联合硬膜外麻醉用于宫颈癌手术的效果良好，有利于稳定患者术中心率、血压，减少手术应激，且术后不良反应少。
Abstract:
Objective To analyze the anesthetic effect, stress response and adverse events of general anesthesia combined with epidural anesthesia in patients with cervical cancer surgery. Methods The clinical data of 84 patients with cervical cancer who underwent laparoscopic surgery in our hospital from July 2015 to July 2017 were selected and divided into two groups according to the random number table method, 42 cases in each group. The control group underwent general anesthesia. The observation group underwent general anesthesia + epidural anesthesia. The anesthetic rate, isoflurane dosage, anesthesia recovery time, post-anesthesia induction, post-pneumoperitoneum, and postoperative stress response were compared. Adverse events occurred. Results The anesthesia rate of the observation group was 92.85%, which was higher than that of the control group (71.43%). The amount of isoflurane in the observation group was (16.21±4.11) ml less than that of the control group (30.74±5.74) ml, and the anesthesia recovery time was (10.21±2.43)min was shorter than the control group (16.91±1.74) min,the difference was statistically significant (P<0.05). The HR of the observation group after induction of anesthesia, after establishment of pneumoperitoneum and at the time of surgery were (80.64±7.53). ) times / min, (77.47 ± 9.78) times / min, (78.52 ± 7.92) times / min lower than the control group (91.39 ± 8.92) times / min, (94.69 ± 7.80) times / min, (93.68 ± 8.47) times/min; the SBP of the observation group were (138.26±11.21) mmHg, (143.23±15.84) mmHg, (145.74±14.09) mmHg, which was lower than that of the control group (146.79±10.41) mmHg, (152.76±14.18) mmHg, ( 156.18±10.21)mmHg, DBP were (76.03±5.26) mmHg, (77.92±8.71) mmHg, (79.81±9.23) mmHg, which was lower than that of the control group (82.56±6.37) mmHg, (93.68±8.34) mmHg, ( 92.31±9.57) mmHg (P<0.05); the adverse reaction rate (11.90%) in the observation group was lower than that in the control group (30.95%) (P<0.05). Conclusion General anesthesia combined with epidural anesthesia is effective for cervical cancer surgery, which is beneficial to stabilize the patient's central rate, blood pressure, surgical stress, and less postoperative adverse reactions.

参考文献/References:

[1]张竣,闫涛,徐静,等.宫颈癌术后脾多肽注射液联合化疗的临床疗效观察[J].现代肿瘤医学,2017,25(21):3494-3496.
[2]田军.全身麻醉联合硬膜外麻醉在宫颈癌患者中的麻醉效果及对应激反应的影响研究[J].中国处方药，2018,16(6):133-134.
[3]李彩芬,王朝红,保建斌.不同麻醉方式对宫颈癌手术围术期的一氧化氮和P物质水平的影响及效果比较[J].中外医学研究,2018,16(7):38-39.
[4]武建,张荣,于春宇,等.全麻复合硬膜外麻醉在妇科快速康复手术中的应用[J].广东医学,2018,39(10):1509-1512.
[5]孙兴兵,王亚军,丁丽丽,等.单纯全麻与全麻复合硬膜外麻醉在妇科腹腔镜手术中的应用效果[J].当代医学,2017,23(5):23-26.
[6]杜建伟.单纯全麻与全麻复合硬膜外麻醉在妇科腹腔镜手术中的麻醉效果的对比分析[J].中国现代药物应用,2016,10(23):144-145.
[7]安玉明,孙轶娜.基于应激反应及血流动力学变化观察不同麻醉方法在妇科腹腔镜手术中的应用[J].检验医学与临床,2017,14(5):670-672.
[8]张从利,邱正国.全麻复合硬膜外麻醉对老年宫颈癌患者术中血压控制及术后血清MCP-1、GSH-Px水平变化的影响[J].中国医药导刊,2017,19(12):1275-1279.
[9]王建花.全麻复合硬膜外麻醉用于妇科腹腔镜手术中的临床效果观察[J].西藏医药,2017,38(5):3-5.
[10]申茜.比较不同麻醉方法用于妇科腹腔镜手术的效果[J].河南外科学杂志,2017,23(4):132-133.

相似文献/References:

[1]廖加群,曹 雪,陈燕平,等.宫颈癌盆腔淋巴结转移分布及危险因素分析[J].医学信息,2018,31(03):25.[doi:10.3969/j.issn.1006-1959.2018.03.008]
　LIAO Jia-qun,CAO Xue,CHEN Yan-ping,et al.Distribution and Risk Factors of Pelvic Lymph Node Metastasis in Cervical Cancer[J].Journal of Medical Information,2018,31(01):25.[doi:10.3969/j.issn.1006-1959.2018.03.008]
[2]徐 洁.宫颈癌筛查及预防的研究进展[J].医学信息,2018,31(09):70.[doi:10.3969/j.issn.1006-1959.2018.09.022]
　XU Jie.Advances in Screening and Prevention of Cervical Cancer[J].Journal of Medical Information,2018,31(01):70.[doi:10.3969/j.issn.1006-1959.2018.09.022]
[3]蔡亚磊,邓思雨,杨 健.宫颈癌放疗增敏的研究现状[J].医学信息,2022,35(09):65.[doi:10.3969/j.issn.1006-1959.2022.09.016]
　CAI Ya-lei,DENG Si-yu,YANG Jian.Research Status of Radiotherapy Sensitization for Cervical Cancer[J].Journal of Medical Information,2022,35(01):65.[doi:10.3969/j.issn.1006-1959.2022.09.016]
[4]车 莹.HPV感染与宫颈病变相关性的研究[J].医学信息,2022,35(09):84.[doi:10.3969/j.issn.1006-1959.2022.09.021]
　CHE Ying.Study on the Correlation Between HPV Infection and Cervical Lesions[J].Journal of Medical Information,2022,35(01):84.[doi:10.3969/j.issn.1006-1959.2022.09.021]
[5]曹 亮,郝 朋,李阳明,等.宫颈癌所致输尿管梗阻患者输尿管支架置入成功率影响因素的Meta分析[J].医学信息,2022,35(09):124.[doi:10.3969/j.issn.1006-1959.2022.09.031]
　CAO Liang,HAO Peng,LI Yang-ming,et al.Meta Analysis of Factors Influencing Success Rate of Ureteral Stent Implantation in Patients with Ureteral Obstruction Caused by Cervical Cancer[J].Journal of Medical Information,2022,35(01):124.[doi:10.3969/j.issn.1006-1959.2022.09.031]
[6]覃念群,刘 楷,米镜霖,等.基于生物信息学分析筛选与宫颈癌预后相关的关键基因[J].医学信息,2022,35(10):8.[doi:10.3969/j.issn.1006-1959.2022.10.002]
　QIN Nian-qun,LIU Kai,MI Jing-lin,et al.Screening Key Genes Related to the Prognosis of Cervical Cancer Based on Bioinformatics Analysis[J].Journal of Medical Information,2022,35(01):8.[doi:10.3969/j.issn.1006-1959.2022.10.002]
[7]黄 花,徐冬冬,章丽霞.TGF-β1在宫颈癌中的研究进展[J].医学信息,2018,31(12):31.[doi:10.3969/j.issn.1006-1959.2018.12.011]
　HUANG Hua,XU Dong-dong,ZHANG Li-xia.Research Progress of TGF-β1 in Cervical Cancer[J].Journal of Medical Information,2018,31(01):31.[doi:10.3969/j.issn.1006-1959.2018.12.011]
[8]夏易曼娜,李虎成.腹腔镜下宫颈癌根治术与传统开腹手术的对比研究[J].医学信息,2018,31(12):115.[doi:10.3969/j.issn.1006-1959.2018.12.036]
　XIA Yi-manna,LI Hu-cheng.Comparative Study of Laparoscopic Radical Resection of Cervical Cancer and Traditional Open Surgery[J].Journal of Medical Information,2018,31(01):115.[doi:10.3969/j.issn.1006-1959.2018.12.036]
[9]杨 军,王翠平,李 龙,等.义安区体检HPV-DNA筛查结果分析[J].医学信息,2018,31(14):136.[doi:10.3969/j.issn.1006-1959.2018.14.041]
　YANG Jun,WANG Cui-ping,LI Long,et al.Analysis of the Results of HPV-DNA Screening in the Medical Examination of Yian District[J].Journal of Medical Information,2018,31(01):136.[doi:10.3969/j.issn.1006-1959.2018.14.041]
[10]王双英,张 娜,刘 芳.具有高危复发因素的早期宫颈癌术后辅助治疗进展[J].医学信息,2018,31(15):33.[doi:10.3969/j.issn.1006-1959.2018.15.012]
　WANG Shuang-ying,ZHANG Na,LIU Fang.Advances in Postoperative Adjuvant Therapy for Early Cervical Cancer with High Risk of Recurrence[J].Journal of Medical Information,2018,31(01):33.[doi:10.3969/j.issn.1006-1959.2018.15.012]

更新日期/Last Update: 2019-01-22