[1]白任然,高 亮,姜 力,等.输尿管软镜碎石术后全身炎症反应综合征的危险因素分析[J].医学信息,2021,34(07):102-105.[doi:10.3969/j.issn.1006-1959.2021.07.028]
　BAI Ren-ran,GAO Liang,JIANG Li,et al.Analysis of Risk Factors of Systemic Inflammatory Response Syndrome After Flexible Ureteroscope Lithotripsy[J].Medical Information,2021,34(07):102-105.[doi:10.3969/j.issn.1006-1959.2021.07.028]
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输尿管软镜碎石术后全身炎症反应综合征的危险因素分析()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
34卷
期数:
2021年07期
页码:
102-105
栏目:
论著
出版日期:
2021-04-01

文章信息/Info

Title:
Analysis of Risk Factors of Systemic Inflammatory Response Syndrome After Flexible Ureteroscope Lithotripsy
文章编号:
1006-1959（2021）07-0102-04
作者:
白任然; 高 亮; 姜 力; 等
（重庆医科大学附属第二医院泌尿外科，重庆 400010）
Author(s):
BAI Ren-ran; GAO Liang; JIANG Li; et al.
(Department of Urology,the Second Affiliated Hospital of Chongqing Medical University,Chongqing 400010,China)
关键词:
输尿管软镜碎石术; 中性粒细胞/淋巴细胞计数比值; 全身炎症反应综合征
Keywords:
Flexible ureteral lithotripsy; Neutrophil/lymphocyte count ratio; Systemic inflammatory response syndrome
分类号:
R699
DOI:
10.3969/j.issn.1006-1959.2021.07.028
文献标志码:
A
摘要:
目的 探讨输尿管软镜碎石术（FUSL）后全身炎症反应综合征（SIRS）的相关危险因素，为预测输尿管软镜碎石术后发生SIRS的风险提供参考。方法 回顾性分析2014年1月~2019年9月于我院接受FUSL手术的369例患者，根据患者术后是否诊断SIRS，分为SIRS组43例和非SIRS组326例，收集两组患者临床资料，采用单因素及多因素Logistic回归分析，确定FUSL术后发生SIRS的独立危险因素，并绘制受试者工作特征曲线（ROC）来验证模型的可靠性。结果 两组术后结石残留、术前LMR、术前NLR比较，差异有统计学意义（P＜0.05），两组年龄、ASA评分、结石负荷、手术时间、术前血肌酐、糖尿病、单侧或双侧手术、术前双J支架置入、PLR值比较，差异无统计学意义（P＞0.05）；Logistic回归分析结果显示，术前NLR和术后结石残留是FUSL术后发生SIRS的独立危险因素（P＜0.05）；ROC曲线显示，术前NLR敏感性为0.65%，特异性为0.78%，阳性预测率为0.19%，阴性预测率为0.94%，AUC为0.779。结论 术前NLR是FUSL术后发生SIRS的独立危险因素，本研究可能为临床医师术前决策或制定医疗方案提供证据支持。
Abstract:
Objective To explore the related risk factors of systemic inflammatory response syndrome (SIRS) after flexible ureteroscopy lithotripsy (FUSL), and to provide references for predicting the risk of SIRS after flexible ureteroscopy lithotripsy.Methods A retrospective analysis of 369 patients who underwent FUSL surgery in our hospital from January 2014 to September 2019.According to whether the patients were diagnosed with SIRS postoperatively, they were divided into 43 cases in the SIRS group and 326 cases in the non-SIRS group. The clinical data of the two groups were collected.Single factor and multivariate Logistic regression analysis were used to determine the independent risk factors for SIRS after FUSL, and the receiver operating characteristic curve (ROC) was drawn to verify the reliability of the model.Results There was a statistically significant difference between the two groups of postoperative stone residual, preoperative LMR, and preoperative NLR (P＜0.05).There was no significant difference between the two groups in age, ASA score, stone load, operation time, preoperative blood creatinine, diabetes, unilateral or bilateral surgery, preoperative double J stent implantation, and PLR value (P＞0.05);Logistic regression analysis showed that preoperative NLR and postoperative stone residual were independent risk factors for SIRS after FUSL (P＜0.05);The ROC curve showed that the sensitivity of preoperative NLR was 0.65%, the specificity was 0.78%, the positive prediction rate was 0.19%, the negative prediction rate was 0.94%, and the AUC was 0.779.Conclusion Preoperative NLR is an independent risk factor for SIRS after FUSL. This study may provide evidence support for clinicians to make preoperative decisions or make medical plans.

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更新日期/Last Update: 1900-01-01