[1]许 鑫.原发性非肌层浸润性膀胱癌的钬激光整块切除与经尿道双极等离子电切术的疗效比较[J].医学信息,2021,34(13):88-91.[doi:10.3969/j.issn.1006-1959.2021.13.022]
　XU Xin.Comparison of the Efficacy of Holmium Laser Resection and Transurethral Bipolar Plasma Resection for Primary Non-myometrial Invasive Bladder Cancer[J].Medical Information,2021,34(13):88-91.[doi:10.3969/j.issn.1006-1959.2021.13.022]
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原发性非肌层浸润性膀胱癌的钬激光整块切除与经尿道双极等离子电切术的疗效比较()

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
34卷
期数:
2021年13期
页码:
88-91
栏目:
论著
出版日期:
2021-07-01

文章信息/Info

Title:
Comparison of the Efficacy of Holmium Laser Resection and Transurethral Bipolar Plasma Resection for Primary Non-myometrial Invasive Bladder Cancer
文章编号:
1006-1959（2021）13-0088-04
作者:
许 鑫
（佳木斯市中心医院泌尿外科，黑龙江 佳木斯 154002）
Author(s):
XU Xin
(Department of Urology,Jiamusi Central Hospital,Jiamusi 154002,Heilongjiang,China)
关键词:
钬激光; 原发性非肌层浸润性膀胱癌; 双极等离子; 血流动力学
Keywords:
Holmium laser; Primary non-muscular invasive bladder cancer; Bipolar plasma; Hemodynamics
分类号:
R737.14
DOI:
10.3969/j.issn.1006-1959.2021.13.022
文献标志码:
A
摘要:
目的 比较原发性非肌层浸润性膀胱癌的激光整块切除与经尿道双极等离子电切术的疗效及对患者血流动力学指标的影响。方法 选取我院2017年1月~2020年7月收治的60例原发性非肌层浸润性膀胱癌患者，随机将分为观察组与对照组，每组30例。对照组行双极等离子电切术，观察组行钬激光整块切除术，比较两组患者手术时间、膀胱冲洗时间、术中出血量、不同时间点SVV、SVI、CI、MAP、HR相关血流动力学指标、生存率、局部复发率及并发症发生情况。结果 两组手术时间比较，差异无统计学意义（P＞0.05）；观察组膀胱冲洗时间、住院时间和术中出血量低于对照组，差异有统计学意义（P＜0.05）；两组手术中SVI、MAP及术后HR比较，差异有统计学意义（P＜0.05）；两组患者1年生存率及局部复发率比较，差异无统计学意义（P＞0.05），观察组2年、3年、5年生存率高于对照组，局部复发率低于对照组（P＜0.05）；观察组并发症发生率为13.33%，低于对照组的43.33%，差异有统计学意义（P＜0.05）。结论 对原发性非肌层浸润性膀胱癌患者分别应用钬激光整块切除术能够优化患者手术指标，稳定血流动力学指标，提升患者远期生存率，减少复发情况，安全性好，值得应用。
Abstract:
Objective To compare the efficacy of laser en bladder resection and transurethral bipolar plasma resection of primary non-muscular invasive bladder cancer and their influence on the hemodynamic parameters of patients.Methods A total of 60 patients with primary non-muscular invasive bladder cancer admitted to our hospital from January 2017 to July 2020 were selected and randomly divided into observation group and control group, with 30 cases in each group.The control group underwent bipolar plasma resection, and the observation group underwent holmium laser en bloc resection. The operation time, bladder irrigation time, intraoperative blood loss, SVV, SVI, CI, MAP, HR related blood at different time points were compared between the two groups. Flow dynamics index, survival rate, local recurrence rate and complications.Results There was no significant difference in operation time between the two groups (P＞0.05);The bladder irrigation time, hospitalization time and intraoperative blood loss in the observation group were lower than those in the control group,the difference was statistically significant (P＜0.05);The comparison of SVI, MAP and postoperative HR between the two groups was statistically significant (P＜0.05);There was no significant difference in the 1year survival rate and local recurrence rate between the two groups of patients (P＞0.05).The 2 years,3 years,5 years survival rate of observation group was higher than control group, local recurrence rate was lower than control group (P＜0.05);The incidence of complications in the observation group was 13.33%, which was lower than 43.33% in the control group,the difference was statistically significant(P＜0.05).Conclusion Holmium laser whole block resection for primary non-myometrial invasive bladder cancer can optimize the surgical index, stabilize hemodynamic index, improve the long-term survival rate, reduce recurrence, and be safe. It is worth applying.

参考文献/References:

[1]曹敬毅,王淇超,孙卫兵,等.钬激光技术治疗非肌层浸润性膀胱癌的临床疗效分析[J].国际泌尿系统杂志,2018,38(2):185-187. [2]王善龙,贺利明,张永升,等.经尿道钬激光切除术与等离子电切术治疗非肌层浸润性膀胱肿瘤的疗效及安全性对比[J].实用癌症杂志,2017,32(8):1345-1347. [3]李益坚,易路,刘文韬,等.经尿道绿激光整块切除非肌层浸润性膀胱肿瘤的随机对照研究[J].临床泌尿外科杂志,2017,32(10):751-754. [4]孙祥生.经尿道膀胱肿瘤电切术与膀胱部分切除术治疗浅表性膀胱癌的临床比照观察[J].中国医疗器械信息,2020,26(15):115,135. [5]张旭辉,王东文,杨森,等.经尿道激光膀胱肿瘤整块切除术72例[J].中国微创外科杂志,2016,16(4):326-328,332. [6]闫伟,乔庐东,杜震,等.经尿道双极等离子针状电极肿瘤整块切除术治疗非肌层浸润性膀胱尿路上皮癌的临床分析[J].中华泌尿外科杂志,2016,37(9):672-675. [7]李益坚,易路,刘文韬,等.经尿道绿激光整块切除非肌层浸润性膀胱肿瘤的随机对照研究[J].临床泌尿外科杂志,2017,32(10):751-754. [8]Jouglar E,Isnardi V,Goulon D,et al.Patterns of locoregional failure in locally advanced non-small cell lung cancer treated with definitive conformal radiotherapy:Results from the Gating 2006 trial[J].Radiotherapy and Oncology,2018,126(2):291-299. [9]王俞,李煜罡,洪健,等.TUR-BT术后膀胱热灌注化疗治疗非肌层浸润性膀胱癌临床应用初探[J].现代泌尿外科杂志,2017,22(12):903-906. [10]中国研究型医院学会,泌尿外科学专业委员会,中国医疗保健国际交流促进会,等.中国非肌层浸润性膀胱癌治疗与监测循证临床实践指南(2018年标准版)[J].现代泌尿外科杂志,2019,24(7):516-542. [11]李雪黎,魏武然,王婷,等.经尿道钬激光切除术与经尿道电切术治疗非肌层浸润性膀胱癌的疗效比较[J].实用医院临床杂志,2018,15(2):211-213. [12]平秦榕,颜汝平,王剑松,等.铥激光联合吡柔比星治疗非肌层浸润性膀胱癌的临床研究[J].国际泌尿系统杂志,2018,38(1):42-45. [13]曹敬毅,王淇超,孙卫兵,等.钬激光技术治疗非肌层浸润性膀胱癌的临床疗效分析[J].国际泌尿系统杂志,2018,38(2):185-187. [14]张朝峰,王冰,杨柳.经尿道钬激光与双极等离子电切治疗非肌层浸润性膀胱癌的疗效比较[J].临床实用医学,2018,36(3):316-318. [15]黄建洪,俞浩,金刚,等.HOLTUR与TURis治疗非肌层浸润性膀胱癌的临床疗效比较[J].中国医师杂志,2018,20(3):460-462.

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更新日期/Last Update: 1900-01-01