[1]杨 萍,袁华兵.三级综合医院多重耐药菌特点及直接经济负担分析[J].医学信息,2022,35(16):132-134.[doi:10.3969/j.issn.1006-1959.2022.16.033]
　YANG Ping,YUAN Hua-bing.Analysis of Characteristics and Direct Economic Burden of Multi-drug Resistant Organisms in Tertiary General Hospitals[J].Journal of Medical Information,2022,35(16):132-134.[doi:10.3969/j.issn.1006-1959.2022.16.033]
点击复制

三级综合医院多重耐药菌特点及直接经济负担分析()

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
35卷
期数:
2022年16期
页码:
132-134
栏目:
调查分析
出版日期:
2022-08-15

文章信息/Info

Title:
Analysis of Characteristics and Direct Economic Burden of Multi-drug Resistant Organisms in Tertiary General Hospitals
文章编号:
1006-1959（2022）16-0132-03
作者:
杨 萍; 袁华兵
（天门市第一人民医院院感科1，药剂科2，湖北 天门 431700）
Author(s):
YANG Ping; YUAN Hua-bing
(Department of Nosocomial Infection Control1,Department of Pharmacy2,Tianmen First People’s Hospital,Tianmen 431700,Hubei,China)
关键词:
多重耐药菌; 直接经济成本; 医院感染
Keywords:
Multi-drug resistant organisms; Direct economic cost; Nosocomial infection
分类号:
R378；R195.4
DOI:
10.3969/j.issn.1006-1959.2022.16.033
文献标志码:
A
摘要:
目的 了解三级综合医院多重耐药菌（MDROs）分布及耐药特点，探讨MDROs相关感染导致的直接经济损失。方法 调查2019年1月-2021年8月我院检出菌株分布及耐药性情况，根据是否检出MDROs分为MDROs组和非MDORs组，分析病原菌检出率、耐药率、住院日及费用情况。结果 CRAB检出率最高，其次为MRCNS、MDR-ECL。MDROs组与非MDROs组CRAB、MRCNS、MRSA、MDR/PDR-PA、CR-KPN、MDR-ECO耐药率比较，差异有统计学意义（P＜0.05）；除MRCNS化验费外，MDROs组与非MDROs组不同菌株间住院日及费用高于非MDROs组，差异有统计学意义（P＜0.05）。结论 医院MDROs病原菌以革兰氏阴性杆菌为主，MDROs感染可增加患者住院日及住院费，增加患者经济负担。
Abstract:
Objective To understand the distribution and drug resistance characteristics of multi-drug resistant organisms (MDROs) in tertiary general hospitals, and to explore the direct economic losses caused by MDROs-related infections.Methods The distribution and drug resistance of strains detected in our hospital from January 2019 to August 2021 were investigated. According to whether MDROs were detected, they were divided into MDROs group and non-MDORs group. The detection rate, drug resistance rate, hospitalization days and cost of pathogenic bacteria were analyzed.Results The detection rate of CRAB was the highest, followed by MRCNS and MDR-ECL. There were significant differences in the drug resistance rates of CRAB, MRCNS, MRSA, MDR/PDR-PA, CR-KPN, MDR-ECO between MDROs group and non-MDROs group (P<0.05). Except for the test cost of MRCNS, the hospitalization days and costs of different strains in MDROs group and non-MDROs group were higher than those in non-MDROs group (P<0.05).Conclusion Gram-negative bacilli are the main pathogens of MDROs in hospitals. MDROs infection can increase the hospitalization days and hospitalization expenses of patients, and increase the economic burden of patients.

参考文献/References:

[1]张敏,万琼,程艳萍,等.综合医院多重耐药菌医院感染SHEL模式防控策略研究[J].重庆医学,2021,50(24):4182-4186.[2]王月华.多学科协作管理在多重耐药菌医院感染防控中的效果[J].中国医药科学,2021,11(5):193-196.[3]周越,杨瑶瑶,张翕,等.基于中国背景的细菌耐药所致健康和经济负担的系统评价[J].中国药房,2021,32(20):2543-2550.[4]全国细菌耐药监测网.2014-2019年耐碳青霉烯类肺炎克雷伯菌流行病学变迁[J].中国感染控制杂志,2021,20(2):175-179.[5]郭轶斌,郭威,邱佩琪,等.多药耐药与非耐药鲍曼不动杆菌院内感染的归因住院费用与住院时长研究[J].中国卫生统计,2017,34(3):378-381.[6]Mauldin PD,Salgado CD,Hansen IS,et al.Attributable hospital cost and length of stay associated with health care-associated in-fections caused by antibiotic-resistant gram-negative bacteria[J].Antimicrob Agents Chemother,2010,54(1):109-115.[7]王芳,孙奇玫,刘欣,等.碳青霉烯类耐药与敏感鲍曼不动杆菌医院感染经济损失的差异[J].中国感染控制杂志,2019,18(9):842-847.[8]卯建,单斌,宋贵波,等.多重耐药鲍曼不动杆菌血流感染的危险因素和预后分析[J].中国感染与化疗杂志,2020,20(1):11-17.[9]刘秋萍,顾晓花,汤瑾,等.泛耐药鲍曼不动杆菌感染的预后危险因素分析[J].临床肺科杂志,2021,26(2):223-229,234.[10]李娜,刘晓霞.多重耐药鲍曼不动杆菌感染的相关危险因素分析[J].安徽医药,2020,24(1):197-201.

相似文献/References:

[1]严飞.肺结核住患者合并多重耐药菌的护理方法及效果观察[J].医学信息,2018,31(01):173.[doi:10.3969/j.issn.1006-1959.2018.01.069]
　YAN fei.Nursing Method and Effect Observation of Multidrug-resistant Bacteria in Hospitalized Patients with Pulmonary Tuberculosis[J].Journal of Medical Information,2018,31(16):173.[doi:10.3969/j.issn.1006-1959.2018.01.069]
[2]李伟杰,陈丽琴,李亚玲,等.儿童医院多重耐药菌耐药情况分析[J].医学信息,2018,31(04):125.[doi:10.3969/j.issn.1006-1959.2018.04.044]
　LI Wei-jie,CHEN Li-qin,LI Ya-ling,et al.Analysis of Multidrug Resistant Bacteria in Children's Hospital[J].Journal of Medical Information,2018,31(16):125.[doi:10.3969/j.issn.1006-1959.2018.04.044]
[3]张丽琴,刘 婷,刘 聪,等.赣南地区临床分离菌耐药性变迁及多重耐药菌的流行变化[J].医学信息,2018,31(05):123.[doi:10.3969/j.issn.1006-1959.2018.05.043]
　ZHANG Li-qin,LIU Ting,LIU Cong,et al.Changes of Drug Resistance of Clinical Isolates and Epidemic Changes of Multidrug-resistant Bacteria in Southern Guizhou[J].Journal of Medical Information,2018,31(16):123.[doi:10.3969/j.issn.1006-1959.2018.05.043]
[4]顾万娟,李 亮,张 振,等.多重耐药菌的临床分布与耐药性分析[J].医学信息,2019,32(15):116.[doi:10.3969/j.issn.1006-1959.2019.15.038]
　GU Wan-juan,LI Liang,ZHANG Zhen,et al.Analysis of Clinical Distribution and Drug Resistance of Multi-drug Resistant Bacteria[J].Journal of Medical Information,2019,32(16):116.[doi:10.3969/j.issn.1006-1959.2019.15.038]

更新日期/Last Update: 1900-01-01