[1]刘 华,程良军,吴琼霞.阴道炎五项指标联合检测在阴道微生态评价中的价值分析[J].医学信息,2022,35(22):89-91.[doi:10.3969/j.issn.1006-1959.2022.22.017]
　LIU Hua,CHENG Liang-jun,WU Qiong-xia.Value Analysis of Combined Detection of Five Indicators of Vaginitis in Vaginal Microecological Evaluation[J].Journal of Medical Information,2022,35(22):89-91.[doi:10.3969/j.issn.1006-1959.2022.22.017]
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阴道炎五项指标联合检测在阴道微生态评价中的价值分析()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
35卷
期数:
2022年22期
页码:
89-91
栏目:
论著
出版日期:
2022-11-15

文章信息/Info

Title:
Value Analysis of Combined Detection of Five Indicators of Vaginitis in Vaginal Microecological Evaluation
文章编号:
1006-1959（2022）22-0089-03
作者:
刘 华; 程良军; 吴琼霞
（1.乐平市妇幼保健院检验科，江西 乐平 333300；2.乐平市人民医院检验科，江西 乐平 333300）
Author(s):
LIU Hua; CHENG Liang-jun; WU Qiong-xia
(1.Laboratory Department of Leping Maternal and Child Health Hospital,Leping 333300,Jiangxi，China;2.Laboratory Department of Leping People’s Hospital,Leping 333300,Jiangxi,China)
关键词:
过氧化氢; 白细胞酯酶; β-葡萄糖醛酸苷酶; 唾液酸酶; 乙酰氨基葡萄糖苷酶; 阴道微生态
Keywords:
Hydrogen peroxide; Leukocyte esterase; β-glucuronidase; Sialidase; N-acetylglucosaminidase; Vaginal microecology
分类号:
R446.1
DOI:
10.3969/j.issn.1006-1959.2022.22.017
文献标志码:
A
摘要:
目的 分析阴道炎五项指标联合检测在阴道微生态评价中的价值。方法 抽选2020年1月-2021年6月本院妇产科门诊就诊的162例患者，均进行阴道分泌物功能酶[过氧化氢（H2O2）、白细胞酯酶（LE）、β-葡萄糖醛酸苷酶（GUS）、唾液酸酶（Sna）、乙酰氨基葡萄糖苷酶（NAG）]测定与常规湿镜检测，比较阴道炎五项指标联合检测与常规湿镜检测的检出阳性率以及菌群正常与菌群异常间五项指标阳性率。结果 菌群正常者92例，菌群异常者70例。阴道炎五项指标联合检测检出阳性率为77.16%，与常规湿镜检测的77.78%比较，差异无统计学意义（P＞0.05）。菌群正常与菌群异常H2O2、LE、GUS、Sna、NAG阳性率比较，差异有统计学意义（P＜0.05）。结论 阴道炎五项指标联合检测操作简便快捷，可有效提示阴道微生态改变，有助于临床早期发现阴道炎。
Abstract:
Objective To analyze the value of combined detection of five indicators of vaginitis in vaginal microecological evaluation.Methods A total of 162 patients who visited the obstetrics and gynecology clinic of our hospital from January 2020 to June 2021 were selected for the determination of vaginal secretion functional enzymes [hydrogen peroxide(H2O2), leukocyte esterase(LE), β-glucuronidase(GUS), sialidase(Sna), N-acetylglucosaminidase (NAG)] and routine wet lens detection. The positive rates of combined detection of five indicators of vaginitis and routine wet lens detection and the positive rates of five indicators between normal flora and abnormal flora were compared.Results There were 92 cases of normal flora and 70 cases of abnormal flora. The positive rate of combined detection of five indicators of vaginitis was 77.16%, which was compared with 77.78% of conventional wet lens detection, the difference was not statistically significant (P>0.05). There were significant differences in the positive rates of H2O2, LE, GUS, Sna and NAG between normal flora and abnormal flora (P<0.05).Conclusion The combined detection of the five indicators of vaginitis is simple and quick, which can effectively prompt the vaginal micro-ecological changes, and is contribute to early clinical detection of vaginitis.

参考文献/References:

[1]Moreira D,Ruiz LS,Leite-Jr DP,et al.Difference Between the Profiles Presented by Yeasts that Colonize the Vaginal Mucosa or Cause Primary or Recurrent Candidiasis[J].Mycopathologia,2021,186(3):411-421.[2]Busharova JV,Vasilev RM,Vasileva SV,et al.PSX-B-22 Humoral factors of protection of the vaginal mucosa in healthy cows and with mycoplasmosis[J].Journal of Animal Science,2021,21(4):78-81.[3]Ylz A,Wen LA,Jbxa B,et al.Prostaglandin E2 stimulates anion and fluid secretion triggered by lipopolysaccharide in rat vaginal epithelium[J].Molecular and Cellular Endocrinology,2021,45(14):64-66.[4]Nicolò S,Tanturli M,Mattiuz G,et al.Vaginal Lactobacilli and Vaginal Dysbiosis-Associated Bacteria Differently Affect Cervical Epithelial and Immune Homeostasis and Anti-Viral Defenses[J].Int J Mol Sci,2021,22(12):6487.[5]Duran-Chávez J,Grandi C,Dos S Rodrigues L,et al.Relationship between metalloproteinase-2 and -9 levels in plasma and vaginal secretion with preterm birth[J].Eur J Obstet Gynecol Reprod Biol,2021,261:217-221.[6]Villa P,Cipolla C,D’Ippolito S,et al.The interplay between immune system and microbiota in gynecological diseases: a narrative review[J].Eur Rev Med Pharmacol Sci,2020,24(10):5676-5690.[7]万俐娟,王慧妍,赵卫东.需养菌性阴道炎的阴道微生态与临床特征分析[J].中国性科学,2020,60(4):314-318.[8]周宗明,张永红,柴建兰,等.22029例门诊妇女阴道微生态的特征分析[J].重庆医科大学学报,2019,18(17):1904-1907.[9]Firdaus S,Hassan N,Mirza MA,et al.FbD directed fabrication and investigation of luliconazole based SLN gel for the amelioration of candidal vulvovaginitis: a 2 T (thermosensitive & transvaginal) approach[J].Saudi Journal of Biological Sciences,2020,37(4):114-115.[10]Xie HQ,Li YB,Tian QC,et al.Two Cu(II)-bearing coordination polymers: magnetic properties and application values on vaginitis by balancing the microbial ecology in the vagina[J].Journal of Polymer Research,2021,12(3):336-342.[11]Thompson A,Timm K,Borders N,et al.Diagnostic performance of two molecular assays for the detection of vaginitis in symptomatic women[J].European Journal of Clinical Microbiology & Infectious Diseases,2020,17(8):1045-1048.[12]Das D,Sarkar B,Mukhopad S,et al.An Altered Ratio of CD4+ And CD8+ T Lymphocytes in Cervical Cancer Tissues and Peripheral Blood-A Prognostic Clue?[J].Asian Pac J Cancer Prev,2020,15(2):189-193.[13]Li J,Duan B,Guo Y,et al.Baicalein sensitizes hepatocellular carcinoma cells to 5-FU and Epirubicin by activating apoptosis and ameliorating P-glycoprotein activity[J].Biomed Pharmacother,2018,98:806-812.[14]李瑞琴,马欢,刘婉.老年性阴道炎患者免疫功能指标的检测及影响患者预后的相关因素分析[J].山西医药杂志,2020,40(20):445-448.[15]蒯守刚,尚忠波,尚乐乐,等.阴道分泌物常规检查联合5项检测系统在阴道炎中的临床应用[J].中国实验诊断学,2020,14(6):467-471.[16]Pek E,Beyazit F,Korkmaz NS.Predictive value of Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio in Patients with Vaginitis[J].Pakistan Journal of Medical Sciences Online,2020,268(4):640-649.[17]焦瑞宝,陈然,周佳丽,等.阴道分泌物干化学法检测在常见阴道疾病诊断中的应用[J].检验医学,2018,33(9):811-814.[18]冯春妮.阴道微生态变化及HPV感染等因素与宫颈病变的相关性研究[D].呼和浩特:内蒙古医科大学,2019.[19]葛国兴,张铭媛.连续3年动态观察某三甲医院女性阴道分泌物五联干化学和镜检联合筛查细菌性阴道病的意义[J].中国卫生检验杂志,2020,26(4):313-316.[20]刘红敏,陈静,居艳梅,等.人乳头瘤病毒感染者的阴道微生态状况分析[J].河北医药,2019,17(12):265-268.

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更新日期/Last Update: 1900-01-01