[1]耿忠杰.补肾调周法在围绝经期综合症中的应用效果[J].医学信息,2022,35(23):147-149.[doi:10.3969/j.issn.1006-1959.2022.23.031]
 GENG Zhong-jie.Application effect of Invigorating Kidney and Regulating Menstruation in Perimenopausal Syndrome[J].Journal of Medical Information,2022,35(23):147-149.[doi:10.3969/j.issn.1006-1959.2022.23.031]
点击复制

补肾调周法在围绝经期综合症中的应用效果()

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
35卷
期数:
2022年23期
页码:
147-149
栏目:
中医中药
出版日期:
2022-12-01

文章信息/Info

Title:
Application effect of Invigorating Kidney and Regulating Menstruation in Perimenopausal Syndrome
文章编号:
1006-1959(2022)23-0147-03
作者:
耿忠杰
(天津市滨海新区汉沽中医医院妇科,天津 300480)
Author(s):
GENG Zhong-jie
(Department of Gynecology,Hangu Hospital of Traditional Chinese Medicine,Binhai New Area,Tianjin 300480,China)
关键词:
补肾调周法围绝经期综合症性激素月经周期
Keywords:
Invigorating kidney and regulating menstruationPerimenopausal syndromeSex hormonesMenstrual cycle
分类号:
R271.11+6
DOI:
10.3969/j.issn.1006-1959.2022.23.031
文献标志码:
A
摘要:
目的 观察补肾调周法治疗围绝经期综合症的临床效果。方法 选取2020年1月-2021年6月在我院诊治的72例围绝经期综合症患者为研究对象,采用随机数字表法分为对照组和观察组,各36例。对照组给予常规激素治疗,观察组在对照组基础上联合补肾调周法治疗,比较两组临床疗效、性激素水平、月经周期、月经经期、中医证候评分及不良反应发生率。结果 观察组治疗总有效率为94.44%,高于对照组的83.33%(P<0.05);两组血清雌二醇(E2)水平均高于治疗前,促卵泡刺激素(FSH)、促黄体生成素(LH)均低于治疗前,且观察组E2高于对照组,FSH、LH低于对照组(P<0.05);观察组月经周期、月经经期均大于对照组(P<0.05);观察组月经紊乱、心烦易怒、头晕头痛、腰膝酸软、失眠多梦、胁痛口苦、阴部干涩各症状评分均低于对照组(P<0.05);两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论 补肾调周法治疗围绝经期综合症效果确切,可减轻患者中医证候症状,改善性激素水平,促进月经周期、月经经期的恢复,且不会增加不良反应。
Abstract:
Objective To observe the clinical effect of invigorating kidney and regulating menstruation on perimenopausal syndrome.Methods A total of 72 patients with perimenopausal syndrome who were treated in our hospital from January 2020 to June 2021 were selected as the study subjects. They were divided into a control group and an observation group by random number table method, with 36 cases in each group. The control group was treated with conventional hormone therapy, and the observation group was treated with invigorating kidney and regulating menstruation therapy on the basis of the control group. The clinical efficacy, sex hormone level, menstrual cycle, menstrual period, TCM syndrome score and incidence of adverse reactions were compared between the two groups.Results The total effective rate of the observation group was 94.44%, which was higher than 83.33% of the control group (P<0.05). The levels of serum estradiol (E2) in the two groups were higher than those before treatment, and the levels of follicle stimulating hormone (FSH) and luteinizing hormone (LH) were lower than those before treatment, while the level of E2 in the observation group was higher than that in the control group, and the levels of FSH and LH were lower than those in the control group (P<0.05). The menstrual cycle and menstrual period of the observation group were greater than those of the control group (P<0.05). The scores of menstrual disorder, irritability, dizziness and headache, soreness and weakness of waist and knees, insomnia and dreaminess, hypochondriac pain, bitter taste in the mouth, and vaginal dryness in the observation group were lower than those in the control group (P<0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05).Conclusion The method of invigorating kidney and regulating menstruation is effective in the treatment of perimenopausal syndrome, which can reduce the symptoms of TCM syndromes, improve the level of sex hormones, promote the recovery of menstrual cycle and menstrual period, and will not increase adverse reactions.

参考文献/References:

[1]王枸允,王敏,鲍水浓.补肾调冲汤配合健康教育在围绝经期综合征中的应用[J].新中医,2016,48(9):117-119.[2]周华,王隆卉.王隆卉运用补肾调周法治疗多囊卵巢综合征不孕经验[J].上海中药杂志,2017,51(5):20-22.[3]何敬月.补肾调周结合清利化瘀法治疗盆腔炎性疾病后遗症的临床观察[J].陕西中医,2016,37(8):1046-1048.[4]蔡艳悦,黄筱紘.激素替代疗法治疗围绝经期综合征患者效果及对血清雌二醇、卵泡刺激素、黄体生成素的影响[J].中国妇幼保健,2016,30(31):5396-5398.[5]邵译萱.周惠芳运用补肾调周法治疗痰湿型多囊卵巢综合征不孕经验[J].安徽中医药大学学报,2017,36(6):41-43.[6]李守勋,赵云,王丽华,等.中西医结合治疗围绝经期综合征疗效观察[J].四川中医,2016,34(4):109-110.[7]徐玉娟.补肾调周法联合低剂量雌孕激素序贯疗法治疗多囊卵巢综合征不孕症的临床研究[D].南京:南京中医药大学,2017.[8]张海英,陈碧慧.施艳秋教授补肾调周论治多囊卵巢综合征[J].长春中医药大学学报,2016,32(3):485-487,488.[9]章新根,蔡海英.更年期综合征中医治疗方剂用药规律挖掘分析及临床应用举隅[J].江西中医药大学学报,2016,28(5):42-45.[10]唐苾芯,吴昆仑,都乐亦,等.滋阴补肾方对围绝经期综合征患者雌激素及雌激素受体的影响[J].上海中医药大学学报,2016,30(2):27-30.[11]钱敏,林晓平,黄东,等.补肾调周法联合激素治疗卵巢储备功能低下的临床研究[J].中国临床药理学杂志,2016,32(6):514-516.[12]Sharma G,Mauvais-Jarvis F,Prossnitz ER.Roles of G protein -coupled estrogen receptor GPER in metabolic regulation[J].J Steroid Biochem Mol Biol,2018,176:31-37.[13]杨丽华.针刺治疗肾阴虚型围绝经期综合征的临床疗效观察[D].广州:广州中医药大学,2016.[14]吴莹,汤晓冬,徐美君,等.穴位埋线对妇女肥胖和围绝经期综合征的疗效观察[J].针灸临床杂志,2016,20(8):287-289.[15]郝朝洪.知柏二地汤治疗阴虚火旺型围绝经期综合征的临床观察[D].昆明:云南中医学院,2018.[16]郝瑞,郭惠岚,梁艳,等.四物汤加减治疗女性更年期综合征疗效观察[J].陕西中医,2016,37(10):1293-1294[17]江曼.针药合用治疗肾阴虚型围绝经期综合征的临床疗效研究[D].广州:广州中医药大学,2018.[18]姚婷.补肾舒更汤配合利维爱治疗围绝经期综合征肾阴阳两虚证的临床观察[D].长沙:湖南中医药大学,2016.

相似文献/References:

[1]吕 琦.激素替代治疗对围绝经期综合征妇女子宫内膜厚度和 激素水平的影响分析[J].医学信息,2018,31(05):133.[doi:10.3969/j.issn.1006-1959.2018.05.047]
 LV Qi.Effect of Hormone Replacement Therapy on Endometrial Thickness and Hormone Level in Women with Perimenopausal Syndrome[J].Journal of Medical Information,2018,31(23):133.[doi:10.3969/j.issn.1006-1959.2018.05.047]

更新日期/Last Update: 1900-01-01