[1]张文欣,张含祺,李 浴,等.剪切波弹性成像技术对乳腺钙化肿块的诊断价值[J].医学信息,2023,36(10):161-164.[doi:10.3969/j.issn.1006-1959.2023.10.036]
 ZHANG Wen-xi,ZHANG Han-qi,LI Yu,et al.Diagnostic Value of Shear Wave Elastography in Breast Calcified Masses[J].Journal of Medical Information,2023,36(10):161-164.[doi:10.3969/j.issn.1006-1959.2023.10.036]
点击复制

剪切波弹性成像技术对乳腺钙化肿块的诊断价值()
分享到:

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
36卷
期数:
2023年10期
页码:
161-164
栏目:
论著
出版日期:
2023-05-15

文章信息/Info

Title:
Diagnostic Value of Shear Wave Elastography in Breast Calcified Masses
文章编号:
1006-1959(2023)10-0161-04
作者:
张文欣张含祺李 浴
(安徽医科大学第一附属医院超声科,安徽 合肥 230022)
Author(s):
ZHANG Wen-xiZHANG Han-qiLI Yuet al.
(Department of Ultrasound,the First Affiliated of Anhui Medical University,Hefei 230022,Anhui,China)
关键词:
剪切波弹性成像钙化乳腺肿块超声
Keywords:
Shear wave elastographyCalcificationBreast massUltrasound
分类号:
R445.1;R737.9
DOI:
10.3969/j.issn.1006-1959.2023.10.036
文献标志码:
A
摘要:
目的 探讨剪切波弹性成像技术(SWE)对伴有钙化的乳腺肿块的诊断价值。方法 收集2020年1月-2022年2月在我院收治的201例女性患者临床资料,共205个乳腺肿块。纳入伴有钙化且BI-RADS分类结果为4a及以上的乳腺肿块193个,其中良性110个,恶性83个。使用SWE技术比较最大弹性值(Emax)和平均弹性值(Emean)在良恶性组中的差异,分析SWE的诊断效能。结果 恶性组的Emax和Emean值高于良性组,差异有统计学意义(P<0.01);Emax和Emean两个指标具有较高的特异度和阳性预测值,分别为90.91%、87.01%及93.64%、90.00%。Emax和Emean的AUC值分别为0.92(0.89~0.96)和0.91(0.87~0.95),两者具有良好且相似的诊断效能。结论 SWE对所有伴钙化的乳腺肿块具有良好的诊断效能,Emax与Emean两弹性指标的特异度均较高,在保证灵敏度的同时,其特异度的提高有利于减少对可疑结节的穿刺活检。
Abstract:
Objective To investigate the diagnostic value of shear wave elastography (SWE) in breast masses with calcification.Methods The clinical data of 201 female patients admitted to our hospital from January 2020 to February 2022 were collected, with a total of 205 breast masses. A total of 193 breast masses with calcification and BI-RADS classification results of 4a and above were included, including 110 benign and 83 malignant. The SWE technique was used to compare the difference between the maximum elasticity value (Emax) and the average elasticity value (Emean) in the benign and malignant groups, and to analyze the diagnostic efficacy of SWE.Results The Emax and Emean values of the malignant group were higher than those of the benign group, and the difference was statistically significant (P<0.01). Emax and Emean had higher specificity and positive predictive value, which were 90.91%, 87.01% and 93.64%, 90.00%, respectively. The AUC values of Emax and Emean were 0.92(0.89-0.96) and 0.91(0.87-0.95), respectively, with good and similar diagnostic efficacy.Conclusion SWE has good diagnostic efficacy for all breast masses with calcification. The specificity of Emax and Emean elasticity indexes is high. While ensuring the sensitivity, the improvement of its specificity is conducive to reducing the biopsy of suspicious nodules.

参考文献/References:

[1]Bray F,Ferlay J,Soerjomataram I.Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries[J].CA Cancer J Clin,2018,68(6):394-424.[2]Bonfiglio R,Granaglia A,Giocondo R.Molecular Aspects and Prognostic Significance of Microcalcifications in Human Pathology: A Narrative Review[J].Int J Mol Sci,2020,22(1):120.[3]Li T,Tang L,Gandomkar Z.Characteristics of Mammographic Breast Density and Associated Factors for Chinese Women: Results from an Automated Measurement[J].J Oncol,2019,2019:4910854.[4]Choi JS,Han BK,Ko EY.Comparison of synthetic and digital mammography with digital breast tomosynthesis or alone for the detection and classification of microcalcifications[J].Eur Radiol,2019,29(1):319-329.[5]Spak DA,Plaxco JS,Santiago L.BI-RADS fifth edition:A summary of changes[J].Diagn Interv Imaging,2017,98(3):179-190.[6]Cantisani V,David E,Barr RG.US-Elastography for Breast Lesion Characterization: Prospective Comparison of US BIRADS, Strain Elastography and Shear wave Elastography[J].Ultraschall Med,2021,42(5):533-540.[7]Mesurolle B,El Khoury M,Chammings F,et al.Breast sonoelastography: Now and in the future[J].Diagn Interv Imaging,2019,100(10):567-577.[8]Chamming’s F,Mesurolle B,Antonescu R.Value of Shear Wave Elastography for the Differentiation of Benign and Malignant Microcalcifications of the Breast[J].AJR Am J Roentgenol,2019,213(2):W85-W92.[9]Sigrist RMS,Liau J,Kaffas AE.Ultrasound Elastography: Review of Techniques and Clinical Applications[J].Theranostics,2017,7(5):1303-1329.[10]Song EJ,Sohn YM,Seo M.Tumor stiffness measured by quantitative and qualitative shear wave elastography of breast cancer[J].Br J Radiol,2018,91(1086):20170830.[11]Yang H,Xu Y,Zhao Y.The role of tissue elasticity in the differential diagnosis of benign and malignant breast lesions using shear wave elastography[J].BMC Cancer,2020,20(1):930.[12]Kim H,Lee J,Kang BJ.What shear wave elastography parameter best differentiates breast cancer and predicts its histologic aggressiveness?[J].Ultrasonography,2021,40(2):265-273.[13]Suvannarerg V,Chitchumnong P,Apiwat W.Diagnostic performance of qualitative and quantitative shear wave elastography in differentiating malignant from benign breast masses, and association with the histological prognostic factors[J].Quant Imaging Med Surg,2019,9(3):386-398.[14]Hari S,Paul SB,Vidyasagar R.Breast mass characterization using shear wave elastography and ultrasound[J].Diagn Interv Imaging,2018,99(11):699-707.[15]Berg WA,Cosgrove DO,Doré CJ.BE1 Investigators. Shear-wave elastography improves the specificity of breast US: the BE1 multinational study of 939 masses[J].Radiology,2012,262(2):435-449.[16]Evans A,Whelehan P,Thomson K.Quantitative shear wave ultrasound elastography: initial experience in solid breast masses[J].Breast Cancer Res,2010,12(6):R104.[17]Gu J,Polley EC,Ternifi R.Individualized-thresholding Shear Wave Elastography combined with clinical factors improves specificity in discriminating breast masses[J].Breast,2020,54:248-255.[18]Zou H,Xue Y,Ou Y.Factors Affecting the Quality of Breast Quasistatic Ultrasound Elastograms[J].J Ultrasound Med,2018,37(7):1701-1712.[19]Park SY,Choi JS,Han BK.Shear wave elastography in the diagnosis of breast non-mass lesions: factors associated with false negative and false positive results[J].Eur Radiol,2017,27(9):3788-3798.[20]Choi SH,Ko EY,Han BK.Effect of Calcifications on Shear-Wave Elastography in Evaluating Breast Lesions[J].Ultrasound Med Biol,2021,47(1):95-103.

相似文献/References:

[1]王羽翎,孙佳威,周显礼.二维及三维实时剪切波弹性成像在乳腺肿块评估中的应用[J].医学信息,2020,33(11):42.[doi:10.3969/j.issn.1006-1959.2020.11.014]
 WANG Yu-ling,SUN Jia-wei,ZHOU Xian-li.Application of 2D and 3D Real-time Shear Wave Elastography in Breast Mass Evaluation[J].Journal of Medical Information,2020,33(10):42.[doi:10.3969/j.issn.1006-1959.2020.11.014]
[2]郭艺旋,张文欣,张含祺,等.剪切波弹性成像在单侧腰椎间盘突出患者坐骨神经评价中的应用[J].医学信息,2022,35(15):144.[doi:10.3969/j.issn.1006-1959.2022.15.034]
 GUO Yi-xuan,ZHANG Wen-xin,ZHANG Han-qi,et al.Application of Shear Wave Elastography in the Evaluation of Sciatic Nerve of Unilateral Lumbar Disc Herniation[J].Journal of Medical Information,2022,35(10):144.[doi:10.3969/j.issn.1006-1959.2022.15.034]
[3]周 波.剪切波弹性成像与实时组织弹性成像技术在甲状腺结节良恶性鉴别诊断中的应用价值[J].医学信息,2022,35(23):156.[doi:10.3969/j.issn.1006-1959.2022.23.034]
 ZHOU Bo.Application Value of Shear Wave Elastography and Real-time Tissue Elastography in Differential Diagnosis of Benign and Malignant Thyroid Nodules[J].Journal of Medical Information,2022,35(10):156.[doi:10.3969/j.issn.1006-1959.2022.23.034]
[4]李 浴,张文欣,张含祺,等.剪切波弹性成像与脉冲多普勒参数在乳腺病变中的诊断性能比较[J].医学信息,2024,37(14):100.[doi:10.3969/j.issn.1006-1959.2024.14.019]
 LI Yu,ZHANG Wen-xin,ZHANG Han-qi,et al.Comparison of Diagnostic Performance of Shear Wave Elastography and Pulsed Wave Doppler Parameters in Breast Lesions[J].Journal of Medical Information,2024,37(10):100.[doi:10.3969/j.issn.1006-1959.2024.14.019]
[5]梁相龙,蒙冬生,黄兴杰,等.血浆致动脉粥样硬化指数与腹主动脉钙化的关系[J].医学信息,2025,38(06):100.[doi:10.3969/j.issn.1006-1959.2025.06.017]
 LIANG Xianglong,MENG Dongsheng,HUANG Xingjie,et al.Relationship Between Atherogenic Index of Plasma and Abdominal Aortic Calcification[J].Journal of Medical Information,2025,38(10):100.[doi:10.3969/j.issn.1006-1959.2025.06.017]

更新日期/Last Update: 1900-01-01