[1]李三林.带状疱疹患者发生后遗神经痛的相关因素研究[J].医学信息,2024,37(08):114-117.[doi:10.3969/j.issn.1006-1959.2024.08.022]
　LI San-lin.Study on Related Factors of Postherpetic Neuralgia in Patients with Herpes Zoster[J].Journal of Medical Information,2024,37(08):114-117.[doi:10.3969/j.issn.1006-1959.2024.08.022]
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带状疱疹患者发生后遗神经痛的相关因素研究()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
37卷
期数:
2024年08期
页码:
114-117
栏目:
论著
出版日期:
2024-04-15

文章信息/Info

Title:
Study on Related Factors of Postherpetic Neuralgia in Patients with Herpes Zoster
文章编号:
1006-1959（2024）08-0114-04
作者:
李三林
（樟树市第二人民医院皮肤科，江西 樟树 331211）
Author(s):
LI San-lin
(Dermatology Department of the Second People’s Hospital of Zhangshu City,Zhangshu 331211,Jiangxi,China)
关键词:
带状疱疹; 后遗神经痛; 年龄; 糖尿病; 早期抗病毒治疗; 皮损面积
Keywords:
Herpes zoster; Postherpetic neuralgia; Age; Diabetes mellitus; Early antiviral treatment; Skin lesion area
分类号:
R752.12
DOI:
10.3969/j.issn.1006-1959.2024.08.022
文献标志码:
A
摘要:
目的 研究带状疱疹患者发生后遗神经痛的相关影响因素。方法 选取2019年1月-2022年12月樟树市第二人民医院收治的68例带状疱疹患者，将出现后遗神经痛的32例患者设为PHN组，另36例设为无PHN组，收集两组基线资料，采用单因素及多因素Logistic分析探索带状疱疹患者发生后遗神经痛的相关影响因素。结果 单因素分析显示，无PHN组与PHN组年龄、皮损面积、急性期疼痛程度、合并糖尿病、前驱疼痛、吸烟史及早期抗病毒治疗情况比较，差异有统计学意义（P＜0.05）。多因素Logistic回归分析显示，年龄≥50岁、皮损面积≥5%、重度急性期疼痛、合并糖尿病是带状疱疹患者后遗神经痛的独立危险因素（P＜0.05，OR＞1），早期抗病毒治疗为带状疱疹患者后遗神经痛的保护因素（P＜0.05，OR＜1）。结论 年龄、皮损面积、急性期疼痛、合并糖尿病及早期抗病毒治疗均为带状疱疹患者后遗神经痛的影响因素。
Abstract:
Objective To study the related influencing factors of postherpetic neuralgia in patients with herpes zoster.Methods A total of 68 patients with herpes zoster admitted to the Second People’s Hospital of Zhangshu City from January 2019 to December 2022 were selected. Thirty-two patients with PHN were set as PHN group, and the other 36 patients were set as non-PHN group. The baseline data of the two groups were collected. Univariate and multivariate logistic analysis was used to explore the related influencing factors of PHN in patients with herpes zoster.Results Univariate analysis showed that there were statistically significant differences in age, lesion area, acute pain degree, diabetes mellitus, prodromal pain, smoking history and early antiviral treatment between the non-PHN group and the PHN group (P<0.05). Multivariate Logistic regression analysis showed that age≥50 years, skin lesion area≥5%, severe acute pain, and diabetes mellitus were independent risk factors for postherpetic neuralgia in patients with herpes zoster (P<0.05, OR>1); early antiviral therapy was a protective factor for postherpetic neuralgia in patients with herpes zoster (P<0.05, OR<1).Conclusion Age, skin lesion area, acute pain, diabetes mellitus and early antiviral therapy are the influencing factors of PHN in patients with herpes zoster.

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更新日期/Last Update: 1900-01-01