[1]周 伟,刘学谦,任 翔,等.柴芩清宁胶囊治疗急性上呼吸道感染的系统评价[J].医学信息,2024,37(17):47-52.[doi:10.3969/j.issn.1006-1959.2024.17.008]
　ZHOU Wei,LIU Xue-qian,REN Xiang,et al.Systematic Evaluation of Chaiqin Qingning Capsule in the Treatment of Acute Upper Respiratory Tract Infection[J].Journal of Medical Information,2024,37(17):47-52.[doi:10.3969/j.issn.1006-1959.2024.17.008]
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柴芩清宁胶囊治疗急性上呼吸道感染的系统评价()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
37卷
期数:
2024年17期
页码:
47-52
栏目:
医学数据科学
出版日期:
2024-09-01

文章信息/Info

Title:
Systematic Evaluation of Chaiqin Qingning Capsule in the Treatment of Acute Upper Respiratory Tract Infection
文章编号:
1006-1959（2024）17-0047-06
作者:
周 伟; 刘学谦; 任 翔; 陈晓勤; 陈道鹏; 彭 妍; 王 磊; 张志良
太仓市中医医院急诊科，江苏 太仓 215400
Author(s):
ZHOU Wei; LIU Xue-qian; REN Xiang; CHEN Xiao-qin; CHEN Dao-peng; PENG Yan; WANG Lei; ZHANG Zhi-liang
Emergency Department of Taicang Hospital of Traditional Chinese Medicine,Taicang 215400,Jiangsu,China
关键词:
柴芩清宁胶囊; 急性上呼吸道感染; 系统评价
Keywords:
Chaiqin Qingning capsule; Acute upper respiratory infection; System evaluation
分类号:
R259
DOI:
10.3969/j.issn.1006-1959.2024.17.008
文献标志码:
A
摘要:
目的 系统评价柴芩清宁胶囊在急性上呼吸道感染（简称上感）中的疗效。方法 检索中国知网、万方数据库、维普网、PubMed、EMbase、Cochrane Library，筛选符合纳入标准的柴芩清宁胶囊治疗上感的随机对照试验（RCT）。检索时限为各库建库时间至2023年5月31日，采用Review Manager 5.3对符合条件的文献进行Meta分析。结果 共纳入7篇RCT，共计1126例受试者。Meta分析提示，试验组临床有效率高于对照组，差异有统计学意义（RR=1.10，95%CI：1.00~1.20，P=0.05）；试验组6、12、48 h体温低于对照组，差异有统计学意义（MD=-0.24，95%CI：-0.33~-0.16，P＜0.000 01；MD=-0.50，95%CI：-0.69~-0.32，P＜0.000 01；MD=-0.46，95%CI：-0.55~-0.38，P＜0.000 01）；两组退热起效时间与完全退热时间比较，差异无统计学意义（MD=-4.07，95%CI：-11.13~2.98，P=0.26；MD=-3.37，95%CI：-7.83~1.10，P=0.14）；两组不良反应事件发生率比较，差异无统计学意义（RR=1.21，95%CI：0.53~2.76，P=0.65）。结论 柴芩清宁胶囊具有较好的退热疗效，且无明显不良反应，临床可用于治疗上感伴有发热的患者。
Abstract:
Objective Objective To systematically evaluate the efficacy of Chaiqin Qingning capsules in the treatment of acute upper respiratory tract infection.Methods CNKI, Wanfang database, VIP, PubMed, EMbase, Cochrane Library were searched to screen randomized controlled trials ( RCTs ) of Chaiqin Qingning capsule in the treatment of upper respiratory tract infection. The retrieval time limit was from the establishment of each database to May 31, 2023. Review Manager 5.3 was used for Meta-analysis of eligible literatures.Results A total of 7 RCTs involving 1126 subjects were included. Meta-analysis showed that the clinical effective rate of the experimental group was higher than that of the control group, and the difference was statistically significant (RR=1.10，95%CI：1.00~1.20，P=0.05); the body temperature of the experimental group was lower than that of the control group at 6, 12 and 48 h, and the difference was statistically significant (MD=-0.24, 95%CI:-0.33 to -0.16, P<0.000 01; MD=-0.50,95%CI:-0.69 to -0.32, P<0.000 01; MD=-0.46, 95%CI:-0.55 to -0.38, P<0.000 01); there was no significant difference in the onset time of feverand the complete antipyretic time between the two groups (MD=-4.07，95%CI：-11.13 to 2.98，P=0.26; MD=-3.37，95%CI：-7.83~1.10，P=0.14); there was no significant difference in the incidence of adverse events between the two groups (RR=1.21, 95%CI:0.53 to 2.76, P=0.65).Conclusion Chaiqin Qingning capsule has good antipyretic effects without obvious adverse events, which can be used for the treatment of upper respiratory tract infection patients with fever.

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更新日期/Last Update: 1900-01-01