[1]姚 灵,木拉力别克·黑扎提,杨文博,等.口面肌-膈肌功能训练对老年轻中度阻塞性睡眠呼吸暂停的疗效研究[J].医学信息,2025,38(09):82-86,104.[doi:10.3969/j.issn.1006-1959.2025.09.015]
　YAO Ling,Mulalibieke·Heizhati,YANG Wenbo,et al.Study on the Effect of Orofacial-diaphragmatic Myofunctional Training on Mild to Moderate Obstructive Sleep Apnea in the Elderly[J].Journal of Medical Information,2025,38(09):82-86,104.[doi:10.3969/j.issn.1006-1959.2025.09.015]
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口面肌-膈肌功能训练对老年轻中度阻塞性睡眠呼吸暂停的疗效研究()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
38卷
期数:
2025年09期
页码:
82-86,104
栏目:
论著
出版日期:
2025-05-01

文章信息/Info

Title:
Study on the Effect of Orofacial-diaphragmatic Myofunctional Training on Mild to Moderate Obstructive Sleep Apnea in the Elderly
文章编号:
1006-1959（2025）09-0082-06
作者:
姚 灵; 木拉力别克·黑扎提; 杨文博; 李南方
新疆维吾尔自治区人民医院高血压中心/新疆高血压研究所/国家卫生健康委高血压诊疗研究重点实验室/新疆维吾尔自治区重点实验室“新疆高血压病研究实验室”/新疆高血压<心脑血管>疾病临床医学研究中心，新疆 乌鲁木齐 830000
Author(s):
YAO Ling;  Mulalibieke·Heizhati;  YANG Wenbo;  LI Nanfang
Hypertension Center of People′s Hospital of Xinjiang Uygur Autonomous Region/Xinjiang Hypertension Institute/NHC Key Laboratory of Hypertension Clinical Research/Key Laboratory of Xinjiang Uygur Autonomous Region "Hypertension Research Laboratory"/Xinjiang Clinical Medical Research Center for Hypertension Diseases, Urumqi 830000, Xinjiang, China
关键词:
口面肌-膈肌功能训练; 阻塞性睡眠呼吸暂停; 呼吸暂停低通气指数
Keywords:
Orofacial-diaphragmatic myofunctional training;  Obstructive sleep apnea;  Apnea hypopnea index
分类号:
R56
DOI:
10.3969/j.issn.1006-1959.2025.09.015
文献标志码:
A
摘要:
目的 探讨口面肌-膈肌功能训练对老年轻中度阻塞性睡眠呼吸暂停（OSA）患者的OSA严重程度、临床症状、睡眠质量及生活质量等方面的治疗效果。方法 选择2021年6月-2022年12月首次就诊于新疆维吾尔自治区人民医院完善多导睡眠监测明确诊断为轻中度OSA的60~80岁老年患者50例，随机分成对照组和口面肌-膈肌功能训练（ODMT）组，每组25例，对照组予以深呼吸训练，ODMT组予以ODMT。比较两组患者基线时和治疗8周后的呼吸暂停低通气指数（AHI）、最低血氧饱和度（LSaO2）、Epworth嗜睡量表（ESS）、匹兹堡睡眠质量指数（PSQI）、柏林问卷（BQ）、健康调查简表（SF-36）评分。结果 基线时两组患者AHI、LSaO2、ESS、PSQI、BQ、SF-36评分比较，差异无统计学意义（P＞0.05）。治疗8周后，ODMT组AHI、ESS评分、BQ评分、PSQI评分低于对照组，SF-36评分中生理机能、生理职能、精力评分高于对照组（P＜0.05）。与基线相比，治疗8周后ODMT组AHI、ESS评分、BQ评分、PSQI评分降低，SF-36评分升高（P＜0.05）。多元线性回归分析显示，ODMT是AHI、ESS、PSQI、BQ评分下降及SF-36评分中生理机能、生理职能、躯体疼痛、精力、精神健康评分升高的独立影响因素（P＜0.05）。结论 口面肌-膈肌功能训练可有效地改善老年轻中度阻塞性睡眠呼吸暂停的AHI、白天嗜睡、打鼾、睡眠质量及生活质量。
Abstract:
Objective To investigate the effects of the orofacial-diaphragmatic myofunctional training on OSA severity, clinical symptoms, sleep quality and quality of life in elderly patients with mild to moderate obstructive sleep apnea (OSA). Methods From June 2021 to December 2022, 50 elderly patients aged 60-80 years who were first diagnosed as mild to moderate OSA by polysomnography in the People’s Hospital of Xinjiang Uygur Autonomous Region were randomly divided into control group and orofacial-diaphragmatic myofunctional training (ODMT) group, with 25 patients in each group. The control group was given deep breathing training, and the ODMT group was given ODMT. The apnea hypopnea index (AHI), lowest arterial oxygen saturation (LSaO2), epworth sleepiness scale (ESS), Pittsburgh sleep quality index (PSQI), Berlin questionnaire (BQ) and 36-item short form survey (SF-36) were compared between the two groups at baseline and 8 weeks after treatment. Results There was no significant difference in AHI, LSaO2, ESS, PSQI, BQ and SF-36 scores between the two groups at baseline (P>0.05). After 8 weeks of treatment, the scores of AHI, ESS, BQ and PSQI in the ODMT group were lower than those in the control group, and the scores of physiological function, physiological function and energy in the SF-36 score were higher than those in the control group (P<0.05). Compared with baseline, AHI, ESS score, BQ score and PSQI score decreased and SF-36 score increased in ODMT group after 8 weeks of treatment (P<0.05). Multivariate linear regression analysis showed that ODMT was an independent influencing factor for the decrease of AHI, ESS, PSQI and BQ scores and the increase of physiological function, physiological function, physical pain, energy and mental health scores in SF-36 score (P<0.05). Conclusion Orofacial-diaphragmatic myofunctional training can effectively improve AHI, daytime sleepiness, snoring, sleep quality and quality of life in elderly patients with mild to moderate obstructive sleep apnea.

参考文献/References:

[1]Zhang Y,Hao W,Fan J,et al.Association Between Obstructive Sleep Apnea and Cardiovascular Events in Acute Coronary Syndrome Patients With or Without Revascularization-A Prospective Cohort Study[J].Circulation Journal,2023,87(10):1369-1379.[2]Gottlieb DJ,Punjabi NM.Diagnosis and Management of Obstructive Sleep Apnea: A Review[J].JAMA,2020,323(14):1389-1400.[3]Salzano G,Maglitto F,Bisogno A,et al.Obstructive sleep apnoea/hypopnoea syndrome: relationship with obesity and management in obese patients[J].Acta Otorhinolaryngologica Italica,2021,41(2):120-130.[4]Ghavami T,Kazeminia M,Ahmadi N,et al.Global Prevalence of Obstructive Sleep Apnea in the Elderly and Related Factors: A Systematic Review and Meta-Analysis Study[J].Journal of Perianesthesia Nursing,2023,38(6):865-875.[5]Lee JJ,Sundar KM.Evaluation and Management of Adults with Obstructive Sleep Apnea Syndrome[J].Lung,2021,199(2):87-101.[6]Wickwire EM,Tom SE,Vadlamani A,et al.Older adult US Medicare beneficiaries with untreated obstructive sleep apnea are heavier users of health care than matched control patients[J].Journal of Clinical Sleep Medicine,2020,16(1):81-89.[7]姚灵,木拉力别克·黑扎提,杨文博,等.老年高血压合并阻塞性睡眠呼吸暂停患者颈围与冠心病相关性分析[J].医学研究杂志,2023,52(10):95-99.[8]Yao L,Heizhati M,Lin M,et al.Elevated body mass index increases the risk of cardiovascular events in hypertensive patients accompanied with obstructive sleep apnea: A cohort study[J].Obesity Research & Clinical Practice,2022,16(6):491-499.[9]Cho JH,Lim YC,Han KD,et al.The incidence of malignant brain tumors is increased in patients with obstructive sleep apnea: A national health insurance survey[J].PLoS One,2020,15(11):e0241598.[10]Seifen C,Pordzik J,Bahr K,et al.Accumulating Comorbidities May Promote Increasing Severity of Obstructive Sleep Apnea with Aging in Males but Not in Females[J].Journal of Personalized Medicine,2022,13(1):79.[11]Silva de Sousa A,Pereira da Rocha A,Brandao Tavares DR,et al.Respiratory muscle training for obstructive sleep apnea: Systematic review and meta-analysis[J].Journal of Sleep Research,2024,33(3):e13941.[12]Hsu B,Emperumal CP,Grbach VX,et al.Effects of respiratory muscle therapy on obstructive sleep apnea: a systematic review and meta-analysis[J].Journal of Clinical Sleep Medicine,2020,16(5):785-801.[13]Sato K,Chitose SI,Sato K,et al.Sleep-related deglutition and respiratory phase patterns in the aged with obstructive sleep apnea under CPAP therapy[J].Acta Otolaryngologica,2020,140(10):861-868.[14]D’Angelo GF,De Mello AAF,Schorr F,et al.Muscle and visceral fat infiltration: A potential mechanism to explain the worsening of obstructive sleep apnea with age[J].Sleep Medicine,2023,104:42-48.[15]Guimar?觔es KC,Drager LF,Genta PR,et al.Effects of oropharyngeal exercises on patients with moderate obstructive sleep apnea syndrome[J].American Journal of Respiratory and Critical Care Medicine,2009,179(10):962-966.[16]Huang Z,Huang D,Liu F,et al.Modified oropharyngeal muscle training and scientific vocalization are effective in treating mild-to-moderate obstructive sleep apnea hypoventilation syndrome in adults[J].Acta Otolaryngologica,2023,143(11-12):989-995.[17]Chen TA,Mao ST,Lin HC,et al.Effects of inspiratory muscle training on blood pressure- and sleep-related outcomes in patients with obstructive sleep apnea: a meta-analysis of randomized controlled trials[J].Sleep and Breathing,2023,27(5):1953-1966.[18]Gell LK,Vena D,Grace K,et al.Drive versus Pressure Contributions to Genioglossus Activity in Obstructive Sleep Apnea[J].Annals of the American Thoracic Society,2023,20(9):1326-1336.[19]Bordoni B,Escher AR,Toccafondi A,et al.Obstructive Sleep Apnea and Role of the Diaphragm[J].Cureus,2022,14(9):e290.

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更新日期/Last Update: 1900-01-01