[1]毛红岩.冠状动脉介入治疗冠心病的疗效及 对患者血清炎症因子的影响[J].医学信息,2018,(10):77-79.[doi:10.3969/j.issn.1006-1959.2018.10.023]
 MAO Hong-yan.Effect of Coronary Intervention on Coronary Heart Disease and its Influence on Serum Inflammatory Factors[J].Medical Information,2018,(10):77-79.[doi:10.3969/j.issn.1006-1959.2018.10.023]
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冠状动脉介入治疗冠心病的疗效及 对患者血清炎症因子的影响()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
期数:
2018年10期
页码:
77-79
栏目:
论著
出版日期:
2018-05-15

文章信息/Info

Title:
Effect of Coronary Intervention on Coronary Heart Disease and its Influence on Serum Inflammatory Factors
文章编号:
1006-1959(2018)10-0077-03
作者:
毛红岩
佳木斯市中心医院心脏内科,黑龙江 佳木斯 154002
Author(s):
MAO Hong-yan
Department of Cardiology,Jiamusi Central Hospital,Jiamusi 154002,Heilongjiang,China
关键词:
PCI冠心病炎症因子
Keywords:
Key words:PCICoronary heart diseaseInflammatory factors
分类号:
R541.4
DOI:
10.3969/j.issn.1006-1959.2018.10.023
文献标志码:
A
摘要:
目的 探讨冠状动脉介入治疗冠心病(CHD)的疗效及对患者血清炎症因子的影响。方法 收集我院自2015年10月~2017年11月收治的CHD患者120例作为观察对象,按治疗方式的不同分为实验组与对照组,每组60例。对照组给予常规药物对症治疗,实验组则给予经皮冠状动脉介入(PCI)治疗,对比两组治疗效果以及治疗前后IL-6、CRP、TNF-α等血清炎症因子变化情况。结果 实验组治疗总有效率为93.33%,高于对照组的78.33%,差异有统计学意义(P<0.05)。治疗前,两组患者血清炎症因子IL-6、CRP、TNF-α水平比较,差异无统计学意义(P>0.05)。治疗后7 d,实验组IL-6为(12.14±3.57)pg/L、CRP为(5.40±2.41)mg/L、TNF-α为(9.61±3.12)ng/ml,均分别低于对照组的(14.02±3.64)pg/L、(8.26±2.58)mg/L、(12.28±3.56)ng/ml,差异有统计学意义(P<0.05)。结论 冠状动脉介入治疗CHD疗效显著,可有效下调患者血清炎症因子水平,促进康复,具有较高的推广价值。
Abstract:
Abstract:Objective To investigate the effect of coronary intervention on coronary heart disease(CHD)and its effect on serum inflammatory factors.Methods A total of 120 patients with CHD admitted to our hospital from October 2015 to November 2017 were collected for observation.According to different treatment methods,the patients were divided into experimental group and control group, with 60 patients in each group.The control group was given symptomatic treatment with conventional drugs.The experimental group was treated with percutaneous coronary intervention(PCI).The effect of treatment and the change of serum inflammatory factors such as IL-6,CRP and TNF-α before and after treatment were compared.Results The total effective rate of the treatment group was 93.33%, which was higher than that of the control group 78.33%,the difference was statistically significant(P<0.05).Before treatment,the levels of serum inflammatory cytokines IL-6,CRP,and TNF-α in the two groups were not statistically different(P>0.05).7 d after treatment, IL-6 in the experimental group was(12.14±3.57)pg/L,CRP was(5.40±2.41)mg/L,and TNF-α was(9.61±3.12)ng/ml,both were significantly lower than the control group(14.02±3.64)pg/L,(8.26±2.58)mg/L,(12.28±3.56)ng/ml,and the difference was statistically significant(P<0.05).Conclusion Coronary interventional therapy for CHD is effective and can effectively reduce the serum inflammatory factor levels and promote rehabilitation.It has a higher value for promotion.

参考文献/References:

[1]时学昆,程璐.老年冠心病患者经桡动脉入路行冠状动脉介入治疗的可行性和安全性[J].中国老年学杂志,2014,34(17):4828-4829.
[2]赵洁,吴俊,贾玫,等.冠心病患者血液脂蛋白相关磷脂酶A2与超敏C反应蛋白及D-二聚体的相关性研究[J].中华检验医学杂志,2014,37(3):227-229.
[3]宋文信,杨成明,曾春雨,等.合并慢性左心衰竭的老年冠心病患者经桡动脉介入治疗的临床评估[J].重庆医学,2010,39(2):191-192.
[4]陈丽芳,宋晓华,黄于朗,等.PCI对冠心病患者血清MMP-9、hs-CRP、HMGB1水平的影响及其预后分析[J].中国实验诊断学,2017,21(10):1714-1717.
[5]罗建军,赖祯平,韦荣耀,等.冠状动脉介入干预对患者血流动力学及血清炎性因子水平的影响[J].中国临床保健杂志,2015,17(4):389-391.
[6]李蕊,王丹丹,苏艳,等.冠心病心绞痛患者经皮冠状动脉介入术后生存质量的影响因素[J].中国老年学杂志,2016,36(10):2379-2380.
[7]马兴瑜.血清超敏C反应蛋白和心肌钙蛋白T检测对冠心病患者经皮冠状动脉介入治疗的临床价值探讨[J].标记免疫分析与临床,2017,24(6):662-665.
[8]杜成林,侯铮,黄骥,等.冠心病患者经皮冠状动脉介入术治疗后血浆IL-12、MCP-1的水平变化[J].医学临床研究,2017,34(1):67-69.
[9]唐秀革.经皮冠状动脉介入治疗老年冠心病临床疗效观察[J].河北医学,2013,19(11):1677-1680.
[10]刘丽军,马燕霞,邵丽荔,等.冠状动脉介入治疗对冠心病血浆高敏C反应蛋白和肿瘤坏死因子α水平的影响[J].心血管康复医学杂志,2013,22(3):230-232.

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更新日期/Last Update: 2018-05-15