[1]贺明清,刘孝娅.环磷腺苷葡胺治疗慢性心力衰竭临床疗效观察[J].医学信息,2018,31(10):135-137.[doi:10.3969/j.issn.1006-1959.2018.10.045]
　HE Ming-qing,LIU Xiao-ya.Clinical Efficacy of Cyclic Adenosine Glucosamine in the Treatment of Chronic Heart Failure[J].Journal of Medical Information,2018,31(10):135-137.[doi:10.3969/j.issn.1006-1959.2018.10.045]
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环磷腺苷葡胺治疗慢性心力衰竭临床疗效观察()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
31卷
期数:
2018年10期
页码:
135-137
栏目:
药物与临床
出版日期:
2018-05-15

文章信息/Info

Title:
Clinical Efficacy of Cyclic Adenosine Glucosamine in the Treatment of Chronic Heart Failure
文章编号:
1006-1959（2018）10-0135-03
作者:
贺明清; 刘孝娅
金堂县中医医院内科，四川 金堂 610400
Author(s):
HE Ming-qing; LIU Xiao-ya
Department of Internal Medicine,Jintang Traditional Chinese Medicine Hospital,Jintang 610400,Sichuan,China
关键词:
环磷腺苷葡胺; 慢性心力衰竭; 心功能
Keywords:
Key words：Cyclic adenosine glucosamine; Chronic heart failure; Cardiac function
分类号:
R541.6
DOI:
10.3969/j.issn.1006-1959.2018.10.045
文献标志码:
A
摘要:
目的 观察分析环磷腺苷葡胺治疗慢性心力衰竭的临床效果。方法 选取2016年1月~2017年2月我院收治的86例慢性心力衰竭患者为研究对象，将其随机分为观察组与对照组，每组43例。对照组给予常规抗心衰治疗，观察组在对照组的基础上给予环磷腺苷葡胺治疗，观察并对比两组患者治疗前后的心功能改善情况及LVEDD、LVESD、LVEF、BNP（脑钠肽）临床指标及不良反应发生情况。结果 观察组的治疗总有效率为93.02%，高于对照组的79.06%，差异有统计学意义（P＜0.05）；观察组接受治疗后的各项心功能指优于对照组，差异有统计学意义（P＜0.05）；两组的不良反应发生率均低，差异无统计学意义。结论 腺苷葡胺治疗慢性心力衰竭能有效改善患者的症状，各项心功能指标改善显著，临床效果显著，且具有一定的安全性，值得临床推广使用。
Abstract:
Abstract：Objective To observe and analyze the clinical effect of cyclic adenosine glucosamine in the treatment of chronic heart failure.Methods 86 patients with chronic heart failure treated in our hospital from January 2016 to February 2017 were selected and divided into the observation group and the control group,43 cases in each group.The control group was treated with normal anti heart failure,and the patients in the observation group were treated with cyclic adenosine glucosamine on the basis of the control group.Observe and compare the two groups of patients before and after treatment of cardiac function improvement and LVEDD,LVESD, LVEF,BNP(brain natriuretic peptide)clinical indicators and adverse reactions.Results The total effective rate of treatment in the observation group was 93.02% which was higher than that in the control group 79.06%,the difference was statistically significant(P< 0.05),the cardiac function index after treatment in the observation group was better than that in the control group,the difference was statistically significant(P<0.05);the incidence of adverse reactions in both groups was low and the difference was not statistically significant.Conclusion The treatment of chronic heart failure with adenosine glucosamine can effectively improve the symptoms of the patients.The indexes of heart function are improved significantly, the clinical effect is remarkable, and it has certain safety.It is worthy of clinical application.

参考文献/References:

[1]葛均波,徐永健.内科学[M].第8版.北京:人民卫生出版社,2013.
[2]李妍.环磷腺苷葡胺治疗充血性心力衰竭疗效观察[J].心血管康复医学杂志,2008,14(2):168-169.
[3]中华医学会心血管病学分会,中华心血管病杂志编辑委员会.慢性心力衰竭诊断治疗指南[J].中华心血管病杂志,2007,35(12):1076-1095.
[4]程康安,吴宁.中国部分地区1980、1990、2000年慢性心力衰竭住院病例回顾性调查[J].中华心血管病杂志,2002,309(8):5-9.
[5]吴静.环磷腺苷葡胺治疗慢性充血性心力衰竭临床研究[J].国外医药抗生素分册,2016,37(3):141-143.
[6]胡加斌.环磷腺苷葡胺治疗老年充血性心力衰竭临床疗效观察[J].亚太传统医药,2012,8(6):161-162.
[7]闫明昌,赵春芝,张东菊.慢性心力衰竭患者6min 步行试验、脑钠肽、左室舒张末期内径、左室射血分数的相关性研究[J].中国实用医药,2012,7(34):5-7.

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更新日期/Last Update: 2018-05-15