[1]孙甫,杨姣,吴文焕,等.转基因动物模型制作进展[J].医学信息,2018,31(01):35-37.[doi:10.3969/j.issn.1006-1959.2018.01.014]
 SUN Fu,YANG Jiao,WU Wen-huan,et al.Development of Transgenic Animal Models[J].Journal of Medical Information,2018,31(01):35-37.[doi:10.3969/j.issn.1006-1959.2018.01.014]
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转基因动物模型制作进展()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
31卷
期数:
2018年01期
页码:
35-37
栏目:
综述
出版日期:
2018-01-01

文章信息/Info

Title:
Development of Transgenic Animal Models
文章编号:
1006-1959(2018)01-0035-03
作者:
孙甫1杨姣2吴文焕2王磊1田宇1
1.西安医学院第一附属医院,陕西西安710077曰2.西安医学院,陕西西安710021
Author(s):
SUN Fu1YANG Jiao2WU Wen-huan2WANG Lei1TIAN Yu1
1.First Affiliated Hospital of Xi'an Medical College,Xi'an 710077,Shaanxi,China2.Xi'an Medical College,Xi'an 710021,Shaanxi,China
关键词:
转基因动物模型显微注射法
Keywords:
Key words:TransgeneAnimal modelMicroinjection
分类号:
R-332
DOI:
10.3969/j.issn.1006-1959.2018.01.014
文献标志码:
A
摘要:
转基因动物是应用实验的方法将外源基因导入到早期的胚胎内,使之可以在动物染色体基因组内稳定的整合,并能遗 传给后代的一类动物遥随着转基因技术以及分子遗传学的发展,转基因动物模型逐渐应用在医学科学的各个领域遥本文对转基 因动物模型的几种常用建模方法做一综述,探讨各种不同的转基因动物模型制作方法的优劣遥最后以显微注射法为例简述制 作转基因动物的方法遥
Abstract:
Abstract:Transgenic animals are the experimental methods used to introduce exogenous genes into early embryos so that they can be stably integrated in the genome of animal genomes and can be passed on to offspring animals.With the development of transgenic technology and molecular genetics, transgenic animal models are gradually applied in various fields of medical science.This article reviews several commonly used modeling methods for transgenic animal models and discusses the advantages and disadvantages of various methods for making transgenic animal models. Finally,the microinjection method as an example to describe the method of making transgenic animals

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更新日期/Last Update: 2018-01-22