[1]周高雅,向光红,唐佳宇,等.神经内科重症监护病房医院获得性肺炎 病原菌分布及耐药性分析[J].医学信息,2018,31(11):121-123.[doi:10.3969/j.issn.1006-1959.2018.11.038]
 ZHOU Gao-ya,XIANG Guang-hong,TANG Jia-yu,et al.Distribution and Drug Resistance of Pathogenic Bacteria Isolated from Hospital Acquired Pneumonia in Neurology Intensive Care Unit[J].Journal of Medical Information,2018,31(11):121-123.[doi:10.3969/j.issn.1006-1959.2018.11.038]
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神经内科重症监护病房医院获得性肺炎 病原菌分布及耐药性分析()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
31卷
期数:
2018年11期
页码:
121-123
栏目:
调查分析
出版日期:
2018-06-01

文章信息/Info

Title:
Distribution and Drug Resistance of Pathogenic Bacteria Isolated from Hospital Acquired Pneumonia in Neurology Intensive Care Unit
文章编号:
1006-1959(2018)11-0121-03
作者:
周高雅向光红唐佳宇李 萍李小娟杨松林
湖南省脑科医院神经内科,湖南 长沙 410007
Author(s):
ZHOU Gao-yaXIANG Guang-hongTANG Jia-yuLI PingLI Xiao-juanYANG Song-lin
Department of Neurology,Hunan Brain Hospital,Changsha 410007,Hunan,China
关键词:
重症监护病房医院获得性肺炎病原菌细菌耐药性
Keywords:
Key words:Intensive care unitHospital acquired pneumoniaPathogenic bacteriaBacterial resistance
分类号:
R446.5
DOI:
10.3969/j.issn.1006-1959.2018.11.038
文献标志码:
A
摘要:
目的 探讨神经内科重症监护病房医院获得性肺炎的病原菌分布以及对抗生素的耐药性,为抗感染治疗提供参考。方法 2016年1月~2017年12月入住湖南省第二人民医院神经内科重症监护病房合并院内获得性肺炎的患者79例,采集痰标本进行细菌分离及培养,并对其进行相关药敏试验。结果 共分离出89株病原菌,其中革兰氏阴性菌占87.64%,革兰氏阳性菌10.11%,真菌2.25%。病原菌以鲍曼不动杆菌(24.72%)、肺炎克雷伯菌(19.10%)、铜绿假单胞菌(17.98%),金黄色葡萄球菌为主(8.99%)为主;鲍曼不动杆菌对大部分抗菌药物耐药,铜绿假单胞菌对头孢哌酮舒巴坦和头孢他啶的耐药率较高,肺炎克雷伯菌耐药率低。金黄色葡萄球菌对青霉素耐药率高。结论 HAP致病菌以革兰氏阴性菌为主,其中鲍曼不动杆菌耐药严重,同时也应注意革兰氏阳性菌和真菌感染。
Abstract:
Abstract:Objective To investigate the distribution of pathogenic bacteria and antibiotic resistance in hospital acquired pneumonia in neurology intensive care unit(ICU),and to provide reference for anti-infection therapy.Methods From January 2016 to December 2017,79 patients were admitted to the Department of Neurology,intensive care unit of the second people's hospital of Hunan province and hospital acquired pneumonia.The sputum specimens were collected for bacterial isolation and culture,and related drug susceptibility tests were conducted.Results A total of 89 strains of pathogenic bacteria were isolated,of which Gram-negative bacteria accounted for 87.64%,Gram-positive bacteria 10.11%,Fungi 2.25%.The pathogenic bacteria were mainly Acinetobacter baumannii (24.72%),Klebsiella pneumoniae(19.10%),Pseudomonas aeruginosa(17.98%),Staphylococcus aureus was predominant(8.99%); Acinetobacter baumannii was resistant to most antibacterial agents;Pseudomonas aeruginosa was resistant to cefoperazone sulbactam and ceftazidime;The primary bacteria resistance rate is low.Staphylococcus aureus is highly resistant to penicillin.Conclusion Gram-negative bacteria are the main pathogenic bacteria of HAP,and Acinetobacter baumannii has serious drug resistance.At the same time, attention should be paid to Gram-positive bacteria and fungal infections.

参考文献/References:

[1]翁国虎,周波.神经重症监护病房肺部感染致病菌及耐药性分析[J].中国公共卫生,2013,29(8):1245-1246. [2]H Georges,O Leroy,B Guery,et al.Predisposing factors for nosocomial pneumonia in patients receiving mechanical ventilation and requiring tracheotomy[J].Chest,2000,118(3):767. [3]宿英英,黄旭升,潘速跃,等.神经疾病并发医院获得性肺炎诊治共识[J].中华神经科杂志,2012,45(10):752-756. [4]李岩松,王丽萍.神经内科重症监护病房肺部感染病原菌分布及耐药性分析[J].中国实用神经疾病杂志,2013,16(13):59-60. [5]王晓娟,易有峰,陈有元.重症监护病房肺部感染病原菌的鉴定及耐药性分析[J].中国微生态杂志,2010,22(2):160-163. [6]曾萍,杨荣霞,程明琨,等.ICU气管切开患者肺部感染病原菌分布及耐药性分析[J].中华医院感染学杂志,2012,22(5):1069-1071. [7]杜红丽,高志红,郭连峰.ICU多重耐药菌的分布及耐药性分析[J].现代预防医学,2014,41(21):4029-4030. [8]陈佰义,何礼贤,胡必杰,等.中国鲍曼不动杆菌感染诊治与防控专家共识[J].中华医学杂志,2012,92(2):76-85. [9]Yilmaz GR,Guven T,Guner R,et al.Colistin alone or combined with sulbactam or carbapenem against A.baumannii in ventilator-associated pneumonia[J].Journal of Infection in Developing Countries,2015,9(5):476-485. [10]胡付品,郭艳,朱德妹,等.2016年CHINET细菌耐药性监测[J].中国感染与化疗杂志,2017,17(5):481-491.

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更新日期/Last Update: 2018-06-01