[1]倪凤媛,李青山,刘兰芳,等.复发转移乳腺癌首发转移模式及预后影响因素[J].医学信息,2018,31(12):1-5.[doi:10.3969/j.issn.1006-1959.2018.12.001]
　NI Feng-yuan,LI Qing-shan,LIU Lan-fang,et al.The First Metastatic Model of Metastatic Breast Cancer and the Influencing Factors of its Prognosis[J].Journal of Medical Information,2018,31(12):1-5.[doi:10.3969/j.issn.1006-1959.2018.12.001]
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复发转移乳腺癌首发转移模式及预后影响因素()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
31卷
期数:
2018年12期
页码:
1-5
栏目:
出版日期:
2018-06-15

文章信息/Info

Title:
The First Metastatic Model of Metastatic Breast Cancer and the Influencing Factors of its Prognosis
文章编号:
1006-1959（2018）12-0001-05
作者:
倪凤媛; 李青山; 刘兰芳; 李冠英
河北省承德市承德医学院附属医院肿瘤科，河北 承德 067000
Author(s):
NI Feng-yuan; LI Qing-shan; LIU Lan-fang; LI Guan-ying
Department of Oncology,Affiliated Hospital of Chengde Medical College,Chengde 067000,Hebei,China
关键词:
乳腺恶性肿瘤; 预后; 复发转移乳腺癌
Keywords:
Key words：Malignant tumor of mammary gland; Prognosis; Recurrence and metastasis of breast cancer
分类号:
R737.9
DOI:
10.3969/j.issn.1006-1959.2018.12.001
文献标志码:
A
摘要:
目的 探讨复发转移乳腺癌患者的首发转移模式和预后的影响因素。方法 研究2013 年 1 月1日～2015 年6月31日我院收治的病理诊断的复发转移乳腺癌患者75例，对其首次复发转移模式和影响其预后确诊年龄、复发年龄、部位、淋巴结转移情况、HER-2状况、激素受体情况和转移器官部位数目、治疗手段的相关因素进行回顾性分析。结果 最常见肿瘤转移部位为骨转移25例（33.33%），其次为肺转移17例（22.67%）。单因素分析显示，首次转移部位数目、淋巴结转移数目、HER-2情况及治疗手段和预后相关（P＜0.05）。多因素分析显示，首次转移部位数目、淋巴结转移数目、HER-2情况、治疗手段是复发转移乳腺癌患者预后的独立影响因素（P＜0.05）。结论 乳腺癌患者术后首次复发转移部位常常为骨转移，其次为肺转移、肝转移。HER-2情况、首次复发转移器数目、淋巴结转移数目、治疗手段是影响复发转移乳腺癌患者的独立预后因素。
Abstract:
Abstract：Objective To investigate the influencing factors of the first metastatic pattern and prognosis of patients with recurrent metastatic breast cancer.Methods 75 patients with recurrent metastatic breast cancer diagnosed from January 1，2013 to June,31，2015 were studied for their first recurrence and metastasis patterns,and their age,recurrence age,location,lymph node metastasis,and HER-2 status.The factors related to hormone receptors,number of metastatic organs,and treatment methods were analyzed retrospectively. Results The most common tumor metastasis site was bone metastasis in 25 cases(33.33%),followed by lung metastases in 17 cases (22.67%).Univariate analysis showed that the number of first metastatic sites,number of lymph node metastases,HER-2 status, treatment methods,and prognosis were related(P<0.05).Multivariate analysis showed that the number of first metastatic sites,lymph node metastasis,HER-2 status,and treatment were independent predictors of prognosis in patients with recurrent metastatic breast cancer(P<0.05).Conclusion The first recurrence and metastasis site of breast cancer patients is usually bone metastasis,followed by lung metastasis and liver metastasis.The HER-2 condition,number of first recurrence metastases,number of lymph node metastases, and treatment methods are independent prognostic factors in patients with recurrent metastatic breast cancer.

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更新日期/Last Update: 2018-06-15