[1]毛红岩,宁国贤.冠脉介入治疗对冠心病急性心肌梗死患者 心肌损伤及心室重塑的影响[J].医学信息,2018,31(12):102-104.[doi:10.3969/j.issn.1006-1959.2018.12.031]
　MAO Hong-yan,NING Guo-xian.Effects of Coronary Intervention on Myocardial Injury and Ventricular Remodeling in Patients with Coronary Heart Disease and Acute Myocardial Infarction[J].Journal of Medical Information,2018,31(12):102-104.[doi:10.3969/j.issn.1006-1959.2018.12.031]
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冠脉介入治疗对冠心病急性心肌梗死患者 心肌损伤及心室重塑的影响()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
31卷
期数:
2018年12期
页码:
102-104
栏目:
临床研究
出版日期:
2018-06-15

文章信息/Info

Title:
Effects of Coronary Intervention on Myocardial Injury and Ventricular Remodeling in Patients with Coronary Heart Disease and Acute Myocardial Infarction
文章编号:
1006-1959（2018）12-0102-03
作者:
毛红岩; 宁国贤
佳木斯市中心医院心内科，黑龙江 佳木斯 154002
Author(s):
MAO Hong-yan; NING Guo-xian
Department of Cardiology,Jiamusi Central Hospital,Jiamusi 154002,Heilongjiang,China
关键词:
冠脉介入; 急性心肌梗死; CK-MB; BNP; 心室重塑
Keywords:
Key words：Coronary intervention; Acute Myocardial Infarction; CK-MB; BNP; Ventricular remodeling
分类号:
R541.4
DOI:
10.3969/j.issn.1006-1959.2018.12.031
文献标志码:
A
摘要:
目的 观察冠脉介入治疗对冠心病急性心肌梗死患者心肌损伤及心室重塑的影响。方法 选取我院自2017年9月~12月收治的64例冠心病急性心肌梗死患者作为观察对象，随机分为研究组33例和对照组31例。对照组给予吸氧、镇静、对症治疗，并给予氯吡格雷+阿司匹林口服，研究组在此基础上进行冠脉介入治疗，对比两组CK、CK-MB、BNP及LVEF、LFESV、LVEDV变化情况。结果 在治疗3 d、7 d后，研究组BNP水平均低于对照组，差异有统计学意义（P＜0.05）。研究组CK峰值、CK-MB峰值与对照组比较，差异无统计学意义（P＞0.05），但研究组CK峰值、CK-MB峰值出现时间均短于对照组，差异有统计学意义（P＜0.05）。治疗7 d后，两组患者LVEF均升高，LFESV、LVEDV均降低，且研究组LVEF高于对照组，LFESV、LVEDV低于对照组，差异均有统计学意义（P＜0.05）。结论 冠脉介入治疗冠心病急性心肌梗死患者可降低患者BNP水平，改善患者心肌损伤，促进心室重塑，具有较高的应用价值。
Abstract:
Abstract：Objective To observe the effects of coronary intervention on myocardial injury and ventricular remodeling in patients with acute myocardial infarction.Methods 64 patients with acute myocardial infarction of coronary heart disease from September 2017 to December 2017 were randomly divided into study group 33 cases and control group 31 cases.The control group was given oxygen inhalation, sedative,symptomatic treatment and oral Clopidogrel+Aspirin;The study group was treated with coronary intervention on the basis of this,and the changes of CK,CK-MB,BNP and LVEF,LFESV,LVEDV were compared in the two groups.Results After 3d and 7d of treatment,the levels of BNP in the study group were significantly lower than those in the control group,the difference was statistically significant(P<0.05).There was no significant difference in the peak value of CK and CK-MB between the study group and the control group(P>0.05),but the time of the peak value of CK and CK-MB in the study group was shorter than that in the control group,the difference was statistically significant(P<0.05).After 7d treatment,the two groups were all increased,LFESV,LVEDV decreased,and the study group LVEF was higher than the control group,LFESV and LVEDV were lower than the control group,the difference was statistically significant(P<0.05).Conclusion Coronary intervention in patients with acute myocardial infarction can reduce the level of BNP,improve the myocardial injury and promote ventricular remodeling,which has a high value of application.

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更新日期/Last Update: 2018-06-15