[1]许益芬.三维适型放疗与调强放疗在胸中段食管癌根治性放疗中的 剂量学比较[J].医学信息,2018,31(13):73-76.[doi:10.3969/j.issn.1006-1959.2018.13.021]
　XU Yi-fen.Dosimetric Comparison of Three-dimensional Conformal Radiotherapy and Intensity-Modulated Radiotherapy for Radical Radiotherapy of Middle Thoracic Esophageal Carcinoma[J].Journal of Medical Information,2018,31(13):73-76.[doi:10.3969/j.issn.1006-1959.2018.13.021]
点击复制

三维适型放疗与调强放疗在胸中段食管癌根治性放疗中的 剂量学比较()
分享到：

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
31卷
期数:
2018年13期
页码:
73-76
栏目:
论著
出版日期:
2018-07-01

文章信息/Info

Title:
Dosimetric Comparison of Three-dimensional Conformal Radiotherapy and Intensity-Modulated Radiotherapy for Radical Radiotherapy of Middle Thoracic Esophageal Carcinoma
文章编号:
1006-1959（2018）13-0073-04
作者:
许益芬
宜兴市肿瘤医院放疗科，江苏 宜兴 214206
Author(s):
XU Yi-fen
Department of Radiotherapy,Yixing Cancer Hospital,Yixing 214206,Jiangsu,China
关键词:
食管癌; 放射治疗; 三维适型; 调强放疗; 剂量学
Keywords:
Key words：Esophageal carcinoma; Radiotherapy; Three-dimensional conformal; Intensity-modulated radiotherapy; Dosimetric
分类号:
R735.1
DOI:
10.3969/j.issn.1006-1959.2018.13.021
文献标志码:
A
摘要:
目的 比较胸中段食管癌三维适型放疗与调强放疗对靶区和危及器官的剂量学影响，探讨两种放射治疗方法在胸中段食管癌根治性放疗中重要器官受保护的优劣，寻找食管癌放射治疗的理想计划模式。方法 15例经病理证实胸中段食管鳞癌患者，经体位固定、CT模拟定位扫描成像传输到治疗计划系统、勾画肿瘤体积、临床靶区体积和危及器官。15例病例均做三维适型和调强计划，60 Gy/30次,评估/优化后应用剂量体积直方图比较两种计划对靶区及危及器官的剂量学影响。结果 在相同靶区、相同剂量模式下，对胸中段食管癌患者的放射治疗中，调强放疗对靶区剂量的分布及对危及器官的保护均优于三维适形放疗。结论 胸中段食管鳞癌，长度4~18 cm放射治疗，三维适型/调强放疗对危及器官剂量学的影响有明显差异。同部位的肿瘤受到相同剂量照射情况下，调强放疗对危及器官的影响较三维适型放疗小，靶区剂量分布均匀度好。
Abstract:
Abstract：Objective To compare the effects of three-dimensional radiotherapy and intensity-modulated radiotherapy on the target area and endangered organs in the middle thoracic esophageal carcinoma,and to explore the advantages and disadvantages of two radiotherapy methods in the protection of important organs in radical thoracic esophageal cancer radical radiotherapy looking for an ideal planning model for radiation therapy for esophageal carcinoma.Methods 15 cases of middle thoracic esophageal squamous cell carcinoma confirmed by pathology were transmitted to the treatment plan system,the volume of the tumor,the volume of the clinical target area and the endanger organ by the position fixation and CT simulation.15 cases were subjected to three-dimensional conformal and intensity-modulated plans,60 Gy/30 times.After evaluation/optimization,dose-volume histograms were used to compare the dosimetric effects of the two plans on the target area and the organs at risk.Results In the same target area and the same dose mode, in the radiotherapy of patients with middle thoracic esophageal cancer,intensity-modulated radiotherapy was better than three-dimensional conformal radiotherapy for the distribution of target dose and protection of endangered organs.Conclusion In the middle thoracic esophageal squamous cell carcinoma,4 to 18 cm in length,the effect of three-dimensional conformal/intensity-modulated radiotherapy on the dosimetry of endangered organs was significantly different.When the tumors in the same site were irradiated by the same dose,the effect of intensity-modulated radiotherapy on the organs at risk was smaller than that of three-dimensional adaptive radiotherapy,and the uniformity of dose distribution in the target area was good.

参考文献/References:

[1]殷蔚伯,谷铣之,于子豪,等.肿瘤放射治疗学[M].第4版.北京:中国协和医科大学出版社,2007:4-11. [2]Wu VW C,Kwong DL W,Sham JS T.Target dose conformity in 3-dimensional conformal radiotherapy and intensity modulated radiotherapy[J].Radiotherapy&Oncology,2004,71(2):201-206. [3]Fu WH,Wang LH,Zhou ZM,et al.Comparison of conformal and intensity-modulated techniques for simultaneous integrated boost radiotherapy of upper esophageal carcinoma[J].World Journal of Gastroenterology,2004,10(8):1098-1102. [4]Chandra A,Guerrero TM,Liu HH,et al.Feasibility of using intensity-modulated radiotherapy to improve lung sparing in treatment planning for distal esophageal cancer[J].Radiother Oncol,2005,77(3):247-253. [5]Wu VW,Sham JS,Kwong DL.Inverse planning in three-dimensional conformal and intensity-modulated radiotherapy of mid-thoracic esophageal cancer[J].Br J Radiol,2004,77(919):568-572. [6]张武哲，陈志坚，李德锐，等.胸上段食管癌调强放疗和适型放疗的剂量学比较[J].癌症，2009,28(11)：1127-1131. [7]王军,祝淑钗,韩春,等.胸上段食管癌三维适型和调强放疗剂量学对比研究[J].中华放射肿瘤学杂志，2008,17(4)：275-279. [8]李巧巧,张瑞,张黎,等.食管癌多原发肿瘤调强放疗与三维适型放疗的剂量学对比研究[J].中国肿瘤临床,2012,39(16):1211-1215. [9]徐朋琴,蔡晶,吴建亭,等.胸中下段食管癌三种放疗技术的剂量学比较[J].临床肿瘤学杂志,2012,17(11):1016-1019. [10]刘智华,胡海芹,罗辉,等.食管癌三维适型和调强放疗剂量学对比研究[J].山东医药,2012,52(1):25-27. [11]Zhao J,He YT,Zheng RS,et al.Analysis of esophageal cancer time trends in china[J].Asian Pac J Cancer Prev,2012,20(4):859-862. [12]Liao Z,Wang S,Wei X,et al.Analysis of clinical and dosimetric factors associated with radiation pneumonitis(RP)in patients with non-small-cell lung cancer(NSCLC)treated with concurrent chemotherapy (ConChT)and three dimensional conformal radiotherapy(3dCRT)(68a)[J].Int J Radiat Oncol Biol Phys,2005,63(supplement 1):S41. [13]曲颜丽,吕茵,王巨武,等.胸段食管癌调强放疗与三维适型放疗及常规放疗的剂量学比较研究[J].吉林医学,2010,31(24):4074-4075. [14]殷蔚伯,谷铣之,于子豪,等.肿瘤放射治疗学[M].第4版.北京：中国协和医科大学出版社,2012:6.

相似文献/References:

[1]汪 兵,杜 铭.食管癌微创手术与机器人手术的研究[J].医学信息,2018,31(06):34.[doi:10.3969/j.issn.1006-1959.2018.06.012]
　WANG Bing,DU Ming.Study on Minimally Invasive Surgery and Robotic Surgery for Esophageal Carcinoma[J].Journal of Medical Information,2018,31(13):34.[doi:10.3969/j.issn.1006-1959.2018.06.012]
[2]茹仙古丽·艾尔西丁,木拉提·哈米提,严传波,等.RF和C4.5决策树在食管癌图像分类中的研究[J].医学信息,2018,31(22):51.[doi:10.3969/j.issn.1006-1959.2018.22.015]
　Roxangvl·Arxidin,Murat·Hamit,YAN Chuan-bo,et al.Research on RF and C4.5 Decision Tree in Image Classification of Esophageal Cancer[J].Journal of Medical Information,2018,31(13):51.[doi:10.3969/j.issn.1006-1959.2018.22.015]
[3]万 芳.以贫血为首发症状的消化道恶性肿瘤临床分析[J].医学信息,2018,31(24):175.[doi:10.3969/j.issn.1006-1959.2018.24.054]
　WAN Fang.Clinical Analysis of Digestive Tract Malignancies with Anemia as the First Symptom[J].Journal of Medical Information,2018,31(13):175.[doi:10.3969/j.issn.1006-1959.2018.24.054]
[4]唐武兵,杨 文,陈健智,等.尼妥珠单抗联合调强适形放疗及化疗治疗局部晚期肺鳞癌的研究[J].医学信息,2019,32(20):1.[doi:10.3969/j.issn.1006-1959.2019.20.001]
　TANG Wu-bing,YANG Wen,CHEN Jian-zhi,et al.Study of Nimotuzumab Combined with Intensity-modulated Radiotherapy and Chemotherapy in the Treatment of Locally Advanced Lung Squamous Cell Carcinoma[J].Journal of Medical Information,2019,32(13):1.[doi:10.3969/j.issn.1006-1959.2019.20.001]
[5]郑祖安,程 龙,潘 歆,等.放射治疗相关专业人员个人辐射剂量分析[J].医学信息,2019,32(13):126.[doi:10.3969/j.issn.1006-1959.2019.13.037]
　ZHENG Zu-an,CHENG Long,PAN Xin,et al.Personal Radiation Dose Analysis of Radiotherapy Related Professionals[J].Journal of Medical Information,2019,32(13):126.[doi:10.3969/j.issn.1006-1959.2019.13.037]
[6]张小艳,赵 红,郑穗生,等.食管癌患者放射性肺损伤预测因素分析及其与 COPD的相关性研究[J].医学信息,2019,32(14):68.[doi:10.3969/j.issn.1006-1959.2019.14.022]
　ZHANG Xiao-yan,ZHAO Hong,ZHENG Sui-sheng,et al.Predictive Factors Analysis of Radiation-Induced Lung Injury in Patients with Esophageal Cancer and Its Correlation with COPD[J].Journal of Medical Information,2019,32(13):68.[doi:10.3969/j.issn.1006-1959.2019.14.022]
[7]赵素素,谭洁琼,党 娟.食管癌术后恢复期补液量与术后恢复的关系[J].医学信息,2021,34(04):88.[doi:10.3969/j.issn.1006-1959.2021.04.023]
　ZHAO Su-su,TAN Jie-qiong,DANG Juan.The Relationship Between the Amount of Fluid Supplementation in the Recovery Period and Postoperative Recovery of Esophageal Cancer[J].Journal of Medical Information,2021,34(13):88.[doi:10.3969/j.issn.1006-1959.2021.04.023]
[8]韦军葆,余彬彬.图像融合在现代放疗技术中的应用进展[J].医学信息,2019,32(23):39.[doi:10.3969/j.issn.1006-1959.2019.23.010]
　WEI Jun-bao,YU Bin-bin.Progress in the Application of Image Fusion in Modern Radiotherapy Technology[J].Journal of Medical Information,2019,32(13):39.[doi:10.3969/j.issn.1006-1959.2019.23.010]
[9]潘兴喜,杨 文,李飞龙,等.鼻咽癌咽后淋巴结转移规律对放疗靶区设计的影响[J].医学信息,2019,32(23):107.[doi:10.3969/j.issn.1006-1959.2019.23.029]
　PAN Xing-xi,YANG Wen,LI Fei-long,et al.Effect of Post-Pharyngeal Lymph Node Metastasis on the Design of Radiotherapy Target Area in Nasopharyngeal Carcinoma[J].Journal of Medical Information,2019,32(13):107.[doi:10.3969/j.issn.1006-1959.2019.23.029]
[10]刘建超,陈 杰,闵小川,等.胸部肿瘤放射治疗不同体位固定技术的比较[J].医学信息,2020,33(02):94.[doi:10.3969/j.issn.1006-1959.2020.02.025]
　LIU Jian-chao,CHEN Jie,MIN Xiao-chuan,et al.Comparison of Different Postural Fixation Techniques for Chest Tumor Radiotherapy[J].Journal of Medical Information,2020,33(13):94.[doi:10.3969/j.issn.1006-1959.2020.02.025]
[11]刘 慧,付 雅,皈 燕,等.呼吸动度对食管癌靶区影响及呼吸运动管理策略[J].医学信息,2022,35(12):93.[doi:10.3969/j.issn.1006-1959.2022.12.022]
　LIU Hui,FU Ya,GUI Yan,et al.Effect of Respiratory Movement on Esophagus Cancer Target Volume and Respiratory Motility Management Stratege[J].Journal of Medical Information,2022,35(13):93.[doi:10.3969/j.issn.1006-1959.2022.12.022]

更新日期/Last Update: 2018-07-01