[1]杨玉峰,李 强,曲国红,等.乳腺癌术前巴德枪穿刺检测ER、PR的临床研究[J].医学信息,2018,(13):163-165.[doi:10.3969/j.issn.1006-1959.2018.13.050]
 YANG Yu-feng,LI Qiang,QU Guo-hong,et al.Clinical Study on Preoperative ER and PR Detection of Bard Gun Puncture in Breast Cancer[J].Medical Information,2018,(13):163-165.[doi:10.3969/j.issn.1006-1959.2018.13.050]
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乳腺癌术前巴德枪穿刺检测ER、PR的临床研究()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
期数:
2018年13期
页码:
163-165
栏目:
诊疗技术
出版日期:
2018-07-01

文章信息/Info

Title:
Clinical Study on Preoperative ER and PR Detection of Bard Gun Puncture in Breast Cancer
文章编号:
1006-1959(2018)13-0163-03
作者:
杨玉峰1李 强1曲国红1孔 哲2赵呈祥1
1.山东省济南市市中区人民医院外科,山东 济南 250000; 2.山东大学附属生殖医院病案管理科,山东 济南 250000
Author(s):
YANG Yu-feng1LI Qiang1QU Guo-hong1KONG Zhe2ZHAO Cheng-xiang1
1.Department of Surgery,People's Hospital of Shizhong District,Jinan 250000,Shandong,China; 2.Department of Medical Records,Affiliated to Reproductive Hospital,Shandong University,Jinan 250000,Shandong,China
关键词:
巴德枪穿刺活检乳腺癌雌激素受体孕激素受体
Keywords:
Key words:Bard gunPuncture biopsyBreast cancerEstrogen receptorProgesterone receptor
分类号:
R737
DOI:
10.3969/j.issn.1006-1959.2018.13.050
文献标志码:
A
摘要:
目的 探讨乳腺癌术前巴德枪穿刺活检检测 ER、PR在乳腺癌治疗中的临床应用价值。方法 选取山东省济南市市中区人民医院外科2013年12月~2015年12月36例乳腺癌患者,术前采用巴德枪穿刺获得病理组织,并进行免疫组织化学检测,与术后常规病理免疫组织化学检测结果进行对比。结果 36例乳腺癌患者术前巴德枪穿刺病理组织行免疫组织化学检测结果与术后常规病理检测结果对比发现,ER表达程度差异无统计学意义(P>0.05);PR表达程度差异有统计学意义(P<0.05)。结论 术前巴德枪穿刺获得的组织经免疫组织化学检测可以反映乳腺癌ER、PR的表达以及表达强度,但是PR表达强度却高于术后常规免疫组织化学检测结果,提示采用术前巴德枪穿刺组织检测的PR作为评估内分泌治疗对乳腺癌PR表达的影响时,应考虑与术后常规免疫组织化学检测结果的差异。
Abstract:
Abstract:Objective To investigate the clinical value of ER and PR in the treatment of breast cancer with preoperative Bard gun biopsy.Methods 36 patients with breast cancer were enrolled in the Department of Surgery,Shizhong District People's Hospital,Jinan City,Shandong Province from December 2013 to December 2015.The pathological tissues were obtained by Bard gun puncture before operation,and immunohistochemical examination was performed.The results were compared with the results of routine pathological immunohistochemistry.Results The immunohistochemical results of preoperative Bard gun puncture pathology in 36 patients with breast cancer were compared with the results of routine pathological examination. The difference of ER expression was not statistically significant(P>0.05).The difference of PR expression was statistically significant (P<0.05).Conclusion The tissue obtained by Bard gun puncture before operation can reflect the expression of ER and PR and the expression intensity of breast cancer,but the intensity of PR expression is higher than that of routine immunohistochemistry after surgery,suggesting the use of preoperative Bard gun.When PR is detected by puncture tissue as an assessment of the effect of endocrine therapy on PR expression in breast cancer,differences from postoperative routine immunohistochemistry results should be considered.

参考文献/References:

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更新日期/Last Update: 2018-07-01