[1]黄秋菊.胱抑素C及脂蛋白α在早期糖尿病肾病诊断中的价值研究[J].医学信息,2018,31(14):57-59.[doi:10.3969/j.issn.1006-1959.2018.14.018]
　HUANG Qiu-ju.The Value of Cystatin C and Lipoprotein α in the Diagnosis of Early Diabetic Nephropathy[J].Journal of Medical Information,2018,31(14):57-59.[doi:10.3969/j.issn.1006-1959.2018.14.018]
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胱抑素C及脂蛋白α在早期糖尿病肾病诊断中的价值研究()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
31卷
期数:
2018年14期
页码:
57-59
栏目:
论著
出版日期:
2018-07-15

文章信息/Info

Title:
The Value of Cystatin C and Lipoprotein α in the Diagnosis of Early Diabetic Nephropathy
文章编号:
1006-1959（2018）14-0057-03
作者:
黄秋菊
广西柳州市人民医院营养科，广西 柳州 545006
Author(s):
HUANG Qiu-ju
Department of Nutrition,Liuzhou People’s Hospital,Liuzhou 545006,Guangxi,China
关键词:
胱抑素C; 脂蛋白α; 糖尿病肾病; 尿微量白蛋白/尿肌酐
Keywords:
Key words：Cystatin C; Lipoprotein α; Diabetic nephropathy; Urinary microalbuminuria/urinary creatinine
分类号:
R587.1；R446.1
DOI:
10.3969/j.issn.1006-1959.2018.14.018
文献标志码:
A
摘要:
目的 探讨胱抑素C及脂蛋白α在早期糖尿病肾病诊断中的应用价值。方法 选取2011年8月~2016年8月柳州市人民医院收治的2型糖尿病患者125例为研究对象,根据尿微量白蛋白/尿肌酐的比值分为无DN组69例及早期DN组56例，两组患者记录年龄、身高、体重等，计算体重指数，Cys C通过快速免疫比浊法进行检测，对比两组Cys C、Lp(α)及其他相关指标之间的意义。结果 DN组Cys C（1.49±0.79）mg/L、Lp(α)（292.86±103.62）mg/L，高于无DN组（1.01±0.35）mg/L、（160.2±131.90）mg/L，差异有统计学意义(P＜0.05)，两者是DN发生的独立危险因素。结论 Cys C、Lp(α)与DN的发生发展有相关性，两者联合检测对早期诊断DN有实用价值。
Abstract:
Abstract：Objective To evaluate the value of cystatin C and lipoprotein α in the diagnosis of early diabetic nephropathy.Methods 125 cases of type 2 diabetes patients admitted to Liuzhou People's Hospital from August 2011 to August 2016 were selected as subjects.According to the ratio of urinary microalbuminuria/urinary creatinine,69 cases were in the non-DN group and 56 cases in the early DN group.The age,height,and weight of the two groups were recorded.Body mass index was calculated.Cys C was detected by rapid immunoturbidimetry,and the significance between Cys C,Lp(α)and other related indicators was compared.Results Cys C(1.49±0.79)mg/L、Lp(α)(292.86±103.62)mg/L in DN group was significantly higher than that in non-DN group(1.01±0.35)mg/L、(160.2±131.90)mg/L,and the difference was statistically significant(P<0.05).Both were independent risk factors of DN.Conclusion There is a correlation between Cys,LP(α)and the occurrence and development of DN.The combined detection of Cys,LP(α)is of practical value in the early diagnosis of DN.

参考文献/References:

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更新日期/Last Update: 2018-07-15