[1]金彦青.NPPV治疗慢性阻塞性肺疾病合并 重症呼吸衰竭的临床疗效观察[J].医学信息,2018,31(14):113-115.[doi:10.3969/j.issn.1006-1959.2018.14.033]
　JIN Yan-qing.Clinical Efficacy of NPPV in the Treatment of Chronic Obstructive Pulmonary Disease with Severe Respiratory Failure[J].Journal of Medical Information,2018,31(14):113-115.[doi:10.3969/j.issn.1006-1959.2018.14.033]
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NPPV治疗慢性阻塞性肺疾病合并 重症呼吸衰竭的临床疗效观察()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
31卷
期数:
2018年14期
页码:
113-115
栏目:
临床研究
出版日期:
2018-07-15

文章信息/Info

Title:
Clinical Efficacy of NPPV in the Treatment of Chronic Obstructive Pulmonary Disease with Severe Respiratory Failure
文章编号:
1006-1959（2018）14-0113-03
作者:
金彦青
山东省烟台市第一〇七医院门诊部，山东 烟台 264002
Author(s):
JIN Yan-qing
Department of Outpatient,the 107 Hospital of Yantai,Yantai 264002,Shandong,China
关键词:
NPPV; 慢性阻塞性肺疾病; 重症呼吸衰竭
Keywords:
Key words：NPPV; Chronic obstructive pulmonary disease; Severe respiratory failure
分类号:
R563.9
DOI:
10.3969/j.issn.1006-1959.2018.14.033
文献标志码:
A
摘要:
目的 分析无创正压通气治疗慢性阻塞性肺疾病合并重症呼吸衰竭的临床效果。方法 选择我院2015年3月~2017年4月诊治的慢性阻塞性肺疾病合并重症呼吸衰竭患者86例进行研究，随机分为研究组和对照组，各43例，对照组患者进行常规治疗，研究组在此基础上应用NPPV治疗，对比两组患者的心率、呼吸频率、动脉血气水平、治疗效果和不良反应。结果 研究组患者的心率水平优于对照组[（88.62±1.27）vs（98.37±1.33）]次/min，差异有统计学意义（P＜0.05）；研究组患者呼吸频率低于对照组[（18.24±2.26）vs（27.33±2.71）] 次/min，差异有统计学意义（P＜0.05）；研究组患者PaO2和PaCO2水平均优于对照组，差异有统计学意义（P＜0.05）；研究组治疗总有效率为90.69%，对照组治疗总有效率55.81%，组间比较，差异有统计学意义（P＜0.05）；研究组治疗不良反应率低于对照组，组间比较，差异有统计学意义（P＜0.05）。结论 NPPV在慢性阻塞性肺疾病合并重症呼吸衰竭治疗中发挥了积极的价值，能够改善患者的生理指标，治疗有效率高，不良反应少。
Abstract:
Abstract：Objective To analyze the clinical effect of non-invasive positive pressure ventilation(NIPPV)in the treatment of chronic obstructive pulmonary disease(COPD)with severe respiratory failure.Methods From March 2015 to April 2017,86 patients with chronic obstructive pulmonary disease complicated with severe respiratory failure were randomly divided into study group and control group,43 cases in each.The patients in the study group were treated with NPPV on the basis of routine therapy,and the patients in the control group were treated with routine therapy.The heart rate,respiratory rate,arterial blood gas level,therapeutic effect and adverse reactions were compared between the two groups.Results The heart rate in the study group was significantly higher than that in the control group [(88.62±1.27)vs(98.37±1.33)]times/min,the difference was statistically significant(P<0.05);the respiratory rate in the study group was lower than that in the control group[(18.24±2.26)vs(27.33±2.71)]times/min,the difference was statistically significant(P< 0.05).The Pao2 and PaCO2 levels in the study group were higher than those in the control group,the difference was statistically significant(P<0.05),the total effective rate in the study group was 90.69% and the total effective rate in the control group was 55.81%,the difference was statistically significant(P<0.05).The adverse reaction rate in the study group was lower than that in the control group, and the difference between the two groups was statistically significant(P<0.05).Conclusion NPPV plays a positive role in the treatment of chronic obstructive pulmonary disease(COPD)with severe respiratory failure. NPPV can improve the physiological index of the patients.The effective rate of NPPV is high and the adverse reaction is less.

参考文献/References:

[1]张宗绵,梁伟灿,关紫云,等.无创正压通气在重症监护室急性呼吸衰竭中的应用调查[J].中国当代医药,2016,23(10):161-164. [2]郭欣,许建新.无创正压通气治疗老年慢性阻塞性肺疾病重症呼吸衰竭患者的疗效分析[J].吉林医学,2014,35(26):5768-5769. [3]季江,钱煜东,崔建波.无创正压通气治疗老年慢性阻塞性肺疾病合并重症呼吸衰竭的效果观察[J].黑龙江医学,2014,38(09):1024-1025 [4]Contoli M,Baraldo S,Marku B,et al.Fixed airflow obstruction due to asthma or chronic obstructive pulmonary disease:5-year follow-up[J].The Journal of Allergy and Clinical Immunology,2017,10(4):255-259. [5]干泳华.无创正压通气治疗老年慢性阻塞性肺疾病合并重症呼吸衰竭的临床疗效观察[J].中外医疗,2016,32(30):79-80. [6]吴忠军,唐剑,周魁.无创正压通气治疗老年慢性阻塞性肺疾病合并重症呼吸衰竭的临床效果[J].中国当代医药,2018,25(11):41-43. [7]Izquierdo-Alonso JL,Rodriguez-Gonzálezmoro JM,de Lucas-Ramos P,et al.Prevalence and characteristics of three clinical phenotypes of chronic obstructive pulmonary disease(COPD)[J].Respiratory Medicine,2013,107(5):724-731. [8]李达,余阶洋,周柳芳,等.无创正压通气治疗老年慢性阻塞性肺疾病急性加重期并发重症呼衰对患者血气及炎性指标的影响[J].四川医学,2017,38(07):817-821. [9]王辰,商鸣宇,黄克武,等.有创与无创序贯性机械通气治疗慢性阻塞性肺部疾病所致严重呼吸衰竭的研究[J].中华结核与呼吸杂志,2017,23(14):215-216. [10]沈洋,肖莉.无创正压通气对急性加重期COPD患者痰液及血液炎性因子水平的影响[J].山东医药,2014,54(31):14-17. [11]李玉.无创机械通气治疗慢性阻塞性肺病合并呼吸衰竭疗效观察[J].中国临床实用医学,2016,4(5):41-42.

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更新日期/Last Update: 2018-07-15