[1]秦盼盼.肝素防治紫癜性肾炎的疗效分析[J].医学信息,2018,(17):130-131,134.[doi:10.3969/j.issn.1006-1959.2018.17.040]
 QIN Pan-pan.Therapeutic Effect of Heparin on Prevention and Treatment of Purpuric Nephritis[J].Medical Information,2018,(17):130-131,134.[doi:10.3969/j.issn.1006-1959.2018.17.040]
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肝素防治紫癜性肾炎的疗效分析()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
期数:
2018年17期
页码:
130-131,134
栏目:
药物与临床
出版日期:
2018-09-01

文章信息/Info

Title:
Therapeutic Effect of Heparin on Prevention and Treatment of Purpuric Nephritis
文章编号:
1006-1959(2018)17-0130-03
作者:
秦盼盼
四川大学华西广安医院肾内科,四川 广安 638000
Author(s):
QIN Pan-pan
Department of Nephrology,West China Guang'an Hospital,Sichuan University,Guangan 638000,Sichuan,China
关键词:
肝素紫癜性肾炎防治效果症状消失时间
Keywords:
Key words:HeparinPurpuric nephritisPrevention and treatment effectSymptom disappearance time
分类号:
R692.3+4
DOI:
10.3969/j.issn.1006-1959.2018.17.040
文献标志码:
A
摘要:
目的 探究肝素对紫癜性肾炎的防治效果。方法 选取2017年6月~2018年6月收治的52例紫癜性肾炎患儿,将其随机分为对照组与研究组,各26例。对照组采取常规治疗,研究组加用低分子肝素钙。对比两组患儿的肾炎治疗效果以及皮肤紫癜、关节肿痛、腹痛等症状的消失时间。结果 研究组皮肤紫癜、关节肿痛、腹痛等症状的消失时间均短于对照组,差异有统计学意义(P<0.05);研究组紫癜性肾炎的治疗总有效率96.15%,高于对照组76.92%,差异有统计学意义(P<0.05)。结论 肝素能够改善紫癜性肾炎患儿的临床症状,其对紫癜性肾炎有显著防治效果。
Abstract:
Abstract:Objective To explore the effect of heparin on the prevention and treatment of purpuric nephritis.Methods A total of 52 children with purpuric nephritis admitted from June 2017 to June 2018 were randomly divided into control group and study group,26 cases each.The control group received routine treatment and the study group received low molecular weight heparin calcium.The effects of nephritis treatment and the disappearance of symptoms such as purpura,joint swelling,and abdominal pain were compared between the two groups.Results The disappearance time of skin purpura,joint swelling and pain,abdominal pain and other symptoms in the study group was shorter than that in the control group,the difference was statistically significant(P<0.05).The total effective rate of treatment of purpuric nephritis in the study group was 96.15%,which was higher than that in the control group 76.92%,the difference was statistically significant(P<0.05).Conclusion Heparin can improve the clinical symptoms of children with purpuric nephritis,and it has significant control effect on purpuric nephritis.

参考文献/References:

[1]徐海玲.小剂量肝素预防小儿紫癜性肾炎的临床研究[J].中国医药科学,2018,8(10):48-50. [2]Tian M,Liu C.Heparin calcium treated Henoch-Schnlein purpura nephritis in children through inhibiting hyperfibrinolysis[J].Renal Failure,2015,37(07):1100. [3]陆小云.不同剂量低分子肝素钙治疗儿童紫癜性肾炎对炎性因子、凝血指标、血黏度的影响[J].菏泽医学专科学校学报,2017,29(02):4-7. [4]Abou RJ,Ishak RS,Otrock ZK,et al.Livedoid vasculopathy in a patient with lupus anticoagulant and MTHFR mutation:treatment with low-molecular-weight heparin[J].Journal of Thrombosis&Thrombolysis,2012,34(04):541-544. [5]吴丽云.应用低分子肝素钙预防紫癜性肾炎[J].中国医药科学,2017,7(18):55-57. [6]郭琼芳,张春天.肝素预防过敏性紫癜性肾炎肾损害的临床疗效及安全性观察[J].临床合理用药杂志,2017,10(01):80-81.

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更新日期/Last Update: 2018-09-01