[1]幸世玉.经尿道电切术联合吉西他滨灌注治疗膀胱癌的临床效果分析[J].医学信息,2018,31(20):91-93.[doi:10.3969/j.issn.1006-1959.2018.20.026]
　XING Shi-yu.Clinical Analysis of Transurethral Resection Combined with Gemcitabine Perfusion in the Treatment of Bladder Cancer[J].Medical Information,2018,31(20):91-93.[doi:10.3969/j.issn.1006-1959.2018.20.026]
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经尿道电切术联合吉西他滨灌注治疗膀胱癌的临床效果分析()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
31卷
期数:
2018年20期
页码:
91-93
栏目:
临床研究
出版日期:
2018-10-15

文章信息/Info

Title:
Clinical Analysis of Transurethral Resection Combined with Gemcitabine Perfusion in the Treatment of Bladder Cancer
文章编号:
1006-1959（2018）20-0091-03
作者:
幸世玉
赣南医学院第三附属医院泌尿外科，江西 赣州 341000
Author(s):
XING Shi-yu
Department of Urology,the Third Affiliated Hospital of Gannan Medical College,Ganzhou 341000,Jiangxi,China
关键词:
经尿道电切术; 吉西他滨灌注; 膀胱癌
Keywords:
Transurethral resection; Gemcitabine perfusion; Bladder cancer
分类号:
R737.14
DOI:
10.3969/j.issn.1006-1959.2018.20.026
文献标志码:
A
摘要:
目的 探讨经尿道电切术联合吉西他滨灌注治疗膀胱癌的临床效果。方法 选取2013年2月~2017年3月我院收治的膀胱癌患者90例，根据患者治疗意愿分为A组和B组，每组45例。A组进行经尿道电切术联合吡柔比星灌注，B组进行经尿道电切术联合吉西他滨灌注。比较两组膀胱癌疗效、住院时间、手术前后患者生存质量评分、卡氏评分以及放射性尿道炎、腹泻、白细胞减少等并发症发生率。结果 B组治疗总有效率为75.55%，高于A组的44.44%，差异具有统计学意义（P＜0.05）。手术后，B组生存质量评分和卡氏评分均优于A组，差异具有统计学意义（P＜0.05）。B组住院时间为（10.02±0.12）d，优于A组的（12.14±0.24）d，差异具有统计学意义（P＜0.05）。B组放射性尿道炎、腹泻、白细胞减少的发生率低于A组，差异具有统计学意义（P＜0.05）。结论 行经尿道电切术联合吉西他滨灌注治疗膀胱癌疗效理想，可有效缩短住院时间，减少并发症，提高患者生存质量提高、提升健康水平。
Abstract:
Objective To investigate the clinical effect of transurethral resection combined with gemcitabine perfusion in the treatment of bladder cancer.Methods 90 patients with bladder cancer admitted to our hospital from February 2013 to March 2017 were enrolled. According to the patient’s willingness to treat,they were divided into group A and group B,with 45 cases in each group.Group A underwent transurethral resection with pirarubicin perfusion,and group B underwent transurethral resection with gemcitabine perfusion.The efficacy of the two groups of bladder cancer,length of hospital stay,quality of life score before and after surgery,Karsten score,and incidence of complications such as radiation urethritis,diarrhea,and leukopenia were compared.Results The total effective rate of group B was 75.55%,which was higher than that of group A 44.44%,the difference was statistically significant(P<0.05).After operation,the quality of life score and the Karsten score of group B were better than those of group A,the difference was statistically significant (P<0.05).The hospital stay in group B was(10.02±0.12) d,which was better than that in group A(12.14±0.24)d,the difference was statistically significant(P<0.05).The incidence of radiation urethritis,diarrhea and leukopenia in group B was lower than that in group A,the difference was statistically significant(P<0.05).Conclusion Transurethral resection combined with gemcitabine perfusion for bladder cancer is effective,which can shorten the hospital stay,reduce complications,improve the quality of life and improve the health.

参考文献/References:

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更新日期/Last Update: 2018-11-09