[1]董选忠.美托洛尔联合稳心颗粒治疗心律失常的临床疗效及安全性分析[J].医学信息,2018,31(21):137-140.[doi:10.3969/j.issn.1006-1959.2018.21.039]
　DONG Xuan-zhong.Clinical Efficacy and Safety Analysis of Metoprolol Combined with Wenxin Granule in the Treatment of Arrhythmia[J].Journal of Medical Information,2018,31(21):137-140.[doi:10.3969/j.issn.1006-1959.2018.21.039]
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美托洛尔联合稳心颗粒治疗心律失常的临床疗效及安全性分析()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
31卷
期数:
2018年21期
页码:
137-140
栏目:
药物与临床
出版日期:
2018-11-01

文章信息/Info

Title:
Clinical Efficacy and Safety Analysis of Metoprolol Combined with Wenxin Granule in the Treatment of Arrhythmia
文章编号:
1006-1959（2018）21-0137-04
作者:
董选忠
江西省乐平第二医院心血管科，江西 乐平 333300
Author(s):
DONG Xuan-zhong
Department of Cardiology,Leping Second Hospital,Leping 333300,Jiangxi,China
关键词:
心律失常; 美托洛尔; 稳心颗粒
Keywords:
Arrhythmia; Metoprolol; Wenxin granule
分类号:
R541.7
DOI:
10.3969/j.issn.1006-1959.2018.21.039
文献标志码:
A
摘要:
目的 分析美托洛尔联合稳心颗粒治疗心律失常的临床治疗效果及安全性。方法 选取我院2017年9月~2018年6月收治的心律失常患者60例，随机分为对照组和研究组，每组30例。对照组采用美托洛尔治疗，研究组在对照组基础上联合稳心颗粒治疗，比较两组患者治疗效果，治疗前后rMSSD、SDNN、PNN50、SDNN-index、症状持续时间和发作频率变化，以及不良反应情况。结果 研究组治疗总有效率为93.33%，高于对照组的60.00%，差异具有统计学意义（P＜0.05）。治疗后，研究组rMSSD、SDNN、PNN50、SDNN-index分别为（39.00±18.00）ms、（133.00±29.00）ms、（11.00±5.00）%、（60.00±18.00）ms，均高于对照组的（30.00±12.00）ms、（121.00±10.00）ms、（7.00±4.00）%、（46.00±16.00）ms，差异具有统计学意义（P＜0.05）。治疗后，研究组症状持续时间和发作频率低于对照组，差异具有统计学意义（P＜0.05）。研究组不良反应总发生率为6.67%，低于对照组的30.00%，差异具有统计学意义（P＜0.05）。结论 采用美托洛尔联合稳心颗粒治疗心律失常，疗效显著，可改善心率指标，缩短症状持续时间，降低发作频率，安全性较高。
Abstract:
Objective To analyze the clinical efficacy and safety of metoprolol combined with Wenxin granule in the treatment of arrhythmia.Methods 60 patients with arrhythmia admitted to our hospital from September 2017 to June 2018 were randomly divided into the control group and the study group, with 30 cases in each group. The control group was treated with metoprolol. The study group was treated with Wenxin granule on the basis of the control group. The treatment effect of the two groups was compared. The rMSSD, SDNN, PNN50, SDNN-index, symptom duration and frequency of episodes, as well as adverse reactions.Results The total effective rate of the study group was 93.33%, which was higher than that of the control group 60.00%, the difference was statistically significant(P<0.05). After treatment, the rMSSD, SDNN, PNN50, and SDNN-index of the study group were(39.00±18.00) ms, (133.00±29.00) ms, (11.00±5.00)%, and(60.00±18.00) ms, respectively, which were higher than those of the control group(30.00±12.00) ms, (121.00±10.00) ms, (7.00±4.00)%, (46.00±16.00) ms, the difference was statistically significant (P<0.05). After treatment, the duration of symptoms and the frequency of seizures in the study group were lower than those in the control group, the difference was statistically significant (P<0.05). The total incidence of adverse reactions in the study group was 6.67%, which was lower than that of the control group 30.00%,the difference was statistically significant(P<0.05). Conclusion Metoprolol combined with Wenxin granule are effective in the treatment of arrhythmia, which can improve heart rate, shorten the duration of symptoms, reduce the frequency of attacks, and have higher safety.

参考文献/References:

[1]李宁.稳心颗粒联合美托洛尔治疗老年人冠心病心律失常的疗效观察[J].中西医结合心脑血管病杂志,2016,14(14):1641-1643. [2]王增武,董颖.2015年《AHA心肺复苏与心血管急救指南》解读[J].中国循环杂志,2015,30(s2):8-22. [3]Motoki N,Inaba Y,Matsuzaki S,et al.Successful treatment of rrhythmia-induced cardiomyopathy in an infant with tuberous sclerosis complex[J].BMC Pediatrics,2015,16(1):16. [4]高连杰.美托洛尔联合稳心颗粒对高血压心脏病室性早搏患者的治疗效果和血液流变学分析[J].实用临床医药杂志,2017,21(1):148-149. [5]李春善.稳心颗粒联合美托洛尔对心律失常患者的疗效及心功能指标的影响[J].国际医药卫生导报,2015,21(5):676-678. [6]黄国华,姜孙琰.稳心颗粒联合美托洛尔治疗心律失常的疗效观察[J].海峡药学,2016,28(9):155-156. [7]高春燕.稳心颗粒联合美托洛尔治疗心律失常的临床疗效[J].中外医学研究,2015,13(33):27-29. [8]王敏毓.步长稳心颗粒联合美托洛尔治疗心律失常的疗效观察[J].中西医结合心血管病电子杂志,2015,3(2):78-79. [9]Steinberg BA,Piccini JP.Arrhythmias in 2016: Arrhythmia treatment-evidence catching up with technology[J].Nature Reviews Cardiology,2017,14(2):75-76. [10]沈建忠.稳心颗粒联合美托洛尔治疗心律失常的临床效果[J].中国卫生标准管理,2017,8(6):74-75.

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更新日期/Last Update: 2018-11-20