[1]徐炜棉,郭金莲,王燕琴,等.铁代谢及铁蛋白与心血管疾病关系的现状分析[J].医学信息,2018,31(22):39-42.[doi:10.3969/j.issn.1006-1959.2018.22.012]
　XU Wei-mian,GUO Jin-lian,WANG Yan-qin,et al.Analysis of the Relationship between Iron Metabolism and Ferritin and Cardiovascular Diseases[J].Journal of Medical Information,2018,31(22):39-42.[doi:10.3969/j.issn.1006-1959.2018.22.012]
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铁代谢及铁蛋白与心血管疾病关系的现状分析()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
31卷
期数:
2018年22期
页码:
39-42
栏目:
综述
出版日期:
2018-11-15

文章信息/Info

Title:
Analysis of the Relationship between Iron Metabolism and Ferritin and Cardiovascular Diseases
文章编号:
1006-1959（2018）22-0039-04
作者:
徐炜棉1; 郭金莲1; 王燕琴2; 卢均坤3
（1.佳木斯大学研究生部，黑龙江 佳木斯 154000；2.佳木斯大学校医院超声科，黑龙江 佳木斯 154000；3.佳木斯大学附属第一医院心内二科，黑龙江 佳木斯 154000）
Author(s):
XU Wei-mian1; GUO Jin-lian1; WANG Yan-qin2; LU Jun-kun3
(1.Graduate School of Jiamusi University,Jiamusi 154000,Heilongjiang,China;2.Department of Ultrasound,Jiamusi University Hospital,Jiamusi 154000,Heilongjiang,China;3.Department of Cardiology,Subject Two,the First Affiliated Hospital of Jiamusi University,
关键词:
铁超载; 铁缺乏; 铁蛋白; 心血管疾病
Keywords:
Iron overloadI; Iron deficiency; Ferritin; Cardiovascular diseases
分类号:
R541；R543
DOI:
10.3969/j.issn.1006-1959.2018.22.012
文献标志码:
A
摘要:
铁是一种双面元素，铁稳态的紊乱对部分组织有害。研究表明心脏是受铁代谢紊乱影响的主要器官之一。铁代谢障碍无论是缺乏还是超载，都与心血管疾病的发生率和死亡率增加有关。铁蛋白是研究铁状态的唯一指标，被认为是诊断铁状态的最佳单一测定。就目前研究结果来看，多种心血管疾病与铁代谢紊乱有关，如冠心病、心力衰竭、心肌病、阿霉素导致的心肌损伤及心肌缺血再灌注。明确铁代谢紊乱引起细胞损伤的机制，并进一步研究铁蛋白与铁代谢紊乱所引起的心血管疾病的相关性，可以为临床上提供便捷、准确的检测方法，并可指导临床治疗。
Abstract:
Iron is a double-sided element, and the disorder of iron homeostasis is harmful to some tissues. Studies have shown that the heart is one of the major organs affected by iron metabolism disorders. Iron metabolism disorders, whether lacking or overloading, are associated with an increased incidence of cardiovascular disease and mortality. Ferritin is the only indicator of iron status and is considered to be the best single assay for diagnosing iron status. According to the current research results, a variety of cardiovascular diseases are associated with iron metabolism disorders, such as coronary heart disease, heart failure, cardiomyopathy, myocardial damage caused by doxorubicin, and myocardial ischemia-reperfusion. To clarify the mechanism of cell damage caused by iron metabolism disorder, and further study the correlation between ferritin and cardiovascular diseases caused by iron metabolism disorder, it can provide a convenient and accurate detection method for clinical, and can guide clinical treatment.

参考文献/References:


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更新日期/Last Update: 2018-12-03