[1]曹火留,张 璋,黄学勤.黛力新联合维生素B6治疗伴负性情绪的功能性消化不良临床疗效研究[J].医学信息,2018,31(22):60-63.[doi:10.3969/j.issn.1006-1959.2018.22.017]
　CAO Huo-liu,ZHANG Zhang,HUANG Xue-qin.Efficacy of Deanxit and VitB6 tablets in management of negative emotions in patients with Functional dyspepsia[J].Journal of Medical Information,2018,31(22):60-63.[doi:10.3969/j.issn.1006-1959.2018.22.017]
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黛力新联合维生素B6治疗伴负性情绪的功能性消化不良临床疗效研究()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
31卷
期数:
2018年22期
页码:
60-63
栏目:
论著
出版日期:
2018-11-15

文章信息/Info

Title:
Efficacy of Deanxit and VitB6 tablets in management of negative emotions in patients with Functional dyspepsia
文章编号:
1006-1959（2018）22-0060-04
作者:
曹火留; 张 璋; 黄学勤
（南方医科大学附属云浮市人民医院消化内科，广东 云浮 527300）
Author(s):
CAO Huo-liu; ZHANG Zhang; HUANG Xue-qin
(Department of Gastroenterology,Yunfu People's Hospital,Southern Medical University,Yunfu 527300,Guangdong,China)
关键词:
功能性消化不良; 情绪障碍; 黛力新; 氟哌噻吨美利曲辛片; 维生素B6
Keywords:
Functional dyspepsia; Emotional disorders; Deanxit; Flupentixol and Melitracen Tablets;  Vitamin B6
分类号:
R57；R749
DOI:
10.3969/j.issn.1006-1959.2018.22.017
文献标志码:
A
摘要:
目的 探讨黛力新联合维生素B6片辅助治疗伴负性情绪的功能性消化不良的临床效果, 为功能性消化不良（FD）的临床治疗提供参考。方法 选择云浮市人民医院2016年6月~2018年1月收治的112例伴有抑郁焦虑等负性情绪的FD患者，采用随机数字表法分为观察组和对照组，每组56例，两组患者均给予常规基础治疗，观察组患者在常规治疗的基础上给予黛力新（氟哌噻吨美利曲辛片）、维生素B6片口服治疗，对两组患者治疗后的心理状态采用SDS及SAS量表进行评估，并对躯体症状、总体疗效进行比较和分析。结果 观察组患者SAS评分、SDS评分低于对照组（P＜0.05)；观察组患者躯体症较前缓解（P＜0.05），且治疗组各项评分低于对照组（P＜0.05），观察组治疗总有效率为 92.72%，对照组治疗总有效率为68.52%，差异具有统计学意义（P＜0.05)。结论 对于伴情绪障碍的FD患者，在常规治疗基础上加用氟哌噻吨美利曲辛片联合维生素B6片治疗，可有效减轻患者精神和躯体症状，提高临床疗效。
Abstract:
Objective To investigate the clinical effect of Deanxit combined with vitamin B6 in the treatment of functional dyspepsia with negative emotion, and to provide reference for the clinical treatment of functional dyspepsia(FD). Methods 112 cases of FD patients with negative emotions such as depression and anxiety were selected from Yunfu People's Hospital from June 2016 to January 2018. They were randomly divided into observation group and control group, 56 cases in each group. The patients in the group were given routine basic treatment. The patients in the observation group were given Deanxit (Flupentixol and Melitracen Tablets) tablets and vitamin B6 tablets on the basis of conventional treatment.The psychological status of the two groups of patients after treatment was assessed by SDS and SAS scales, and the physical symptoms and overall efficacy were compared and analyzed. Results The SAS score and SDS score of the observation group were lower than those of the control group(P<0.05). The physical symptoms of the observation group were lower than those of the control group(P<0.05), and the scores of the treatment group were lower than the control group (P<0.05). The total effective rate was 92.72% in the treatment group and 68.52% in the control group,the difference was statistically significant (P<0.05). Conclusion For patients with FD with mood disorders, the addition of Flupentixol and Melitracen Tablets combined with vitamin B6 tablets on the basis of conventional treatment can effectively reduce the mental and physical symptoms of patients and improve clinical efficacy.

参考文献/References:


[1]Miwa H,Ghoshal UC,Gonlachanvit S,et al.Asian consensus report on functional dyspepsia[J]. J Neurogastroenterol Motil,2012,18(2):150-168.
[2]朱海涛.氟哌噻吨美利曲辛辅助治疗功能性消化不良疗效观察[J].中国冶金工业医学杂志,2018,35（4):443-444.
[3]Zhen-Peng Huang,Xian-Fen Yang,Li-Sa Lan,et al.Correlation between social factors and anxietydepression in function dyspepsia: do relationships exist [J].Prz Gastroenterol, 2014,9(6):348-353.
[4]宋黎明.兰索拉唑联合氟哌噻吨美利曲辛治疗功能性消化不良的疗效观察[J].中国临床新医学, 2018,11(3):265-268.
[5]刘红芬,常丽丽.氟哌噻吨美利曲辛联合常规治疗用于胃食管反流病的疗效观察[J].临床合理用药杂志,2013,6(5):58-59.
[6]李素珍.联合用药治疗功能性消化不良临床疗效观察[J].转化医学电子杂志,2015,2(5):81-82.
[7]Oustamanolakis P,Tack J.Dyspepsia: organic versus functional[J].J Clin Gastroenterol,2012,46(3):175-190.
[8]Ghoshal UC,Singh R,Chang FY,et al.Epidemiology of uninvestigated and functional dyspepsia in Asia: facts and fiction[J].J Neurogastroenterol Motil,2011,17(3):235-244.
[9]罕丽芳.浅谈功能性胃肠病流行病学及其相关因素调查研究[J].心血管病防治知识,2016,1(14):146-148.
[10]黄振鹏,梁仲惠,李锦丽,等.复方枸橼酸阿尔维林治疗慢性非萎缩性胃炎随机对照临床研究[J].中国医药杂志,2014,9(3):73-76.
[11]侯立新,李爽,洪尚游,等.复方阿嗪米特肠溶片与复方消化酶分别联合氟哌噻吨美利曲辛片治疗化学性消化不良的效果比较[J].中国当代医药,2017,24(36):96-101.
[12]陈香宇,张东辉,李淑英.小剂量米氮平联合氟哌噻吨美利曲辛片治疗功能性消化不良并心理障碍疗效观察[J].中华实用诊断与治疗杂志,2012,26(6):584-585.
[13]刘红芬,常丽丽.氟哌噻吨美利曲辛联合常规治疗用于胃食管反流病的疗效观察[J].临床合理用药杂志,2013(6):58-59.
[14]郭秋霞,彭娜,吕飞,等.黛力新对功能性消化不良患者治疗后焦虑和抑郁的改善作用[J].世界华人消化杂志,2015,23(2):324-327.

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更新日期/Last Update: 2018-12-03