[1]谢世宇,程贤高,丁 丹.PICU危重患儿预后危险因素分析[J].医学信息,2018,31(22):107-109.[doi:10.3969/j.issn.1006-1959.2018.22.029]
　XIE Shi-yu,CHENG Xian-gao,DING Dan.Analysis of Prognostic Risk Factors in Critically Ill Children with PICU[J].Journal of Medical Information,2018,31(22):107-109.[doi:10.3969/j.issn.1006-1959.2018.22.029]
点击复制

PICU危重患儿预后危险因素分析()
分享到：

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
31卷
期数:
2018年22期
页码:
107-109
栏目:
临床研究
出版日期:
2018-11-15

文章信息/Info

Title:
Analysis of Prognostic Risk Factors in Critically Ill Children with PICU
文章编号:
1006-1959（2018）22-0107-03
作者:
谢世宇; 程贤高; 丁 丹
（安徽医科大学附属安庆医院儿科，安徽 安庆 246000）
Author(s):
XIE Shi-yu; CHENG Xian-gao; DING Dan
(Department of Pediatrics,Anqing Hospital Affiliated to Medical University Of Anhui,Anqing 246000,Anhui,China)
关键词:
危重症; 预后; 危险因素; 儿童
Keywords:
Critical illness; Prognosis; Risk factors; Children
分类号:
R720.597
DOI:
10.3969/j.issn.1006-1959.2018.22.029
文献标志码:
A
摘要:
目的 通过对我院近4年来150例PICU危重患儿的病例进行剖析，总结影响预后的相关因素。方法 收集150例2014年3月~2018年5月于我院PICU住院治疗危重患儿的临床资料作为研究对象，按预后不同，分为生存组97例和终点事件组53例，对比两组患儿在降钙素原、乳酸脱氢酶、血钙、血乳酸及血 pH 值水平的差异。结果 两组患儿的年龄和性别比较，差异无统计学意义（P＞0.05）。生存组患儿降钙素原、乳酸脱氢酶和血乳酸分别为（0.72±0.31）ng/ml、（75.43±28.88）IU/L和（4.71±1.88）mmol/L，均低于终点事件组的（1.98±0.92）ng/ml、（119.2±49.89）IU/L和（8.46±2.98）mmol/L；血钙和血pH值分别为（1.41±0.55）mmol/L和（7.23±0.20），高于终点事件组的（1.13±0.42）mmol/L和（7.05±0.15），差异均具有统计学意义（P＜0.05）。结论 对于降钙素原、乳酸脱氢酶、血乳酸明显升高，血钙值低和严重酸中毒患儿，生存质量及预后差，死亡风险上升，这些临床指标对PICU危重患儿预后具有重要的临床指导意义。
Abstract:
Objective To analyze the related factors affecting prognosis by analyzing 150 cases of PICU critically ill children in our hospital in the past 4 years.Methods A total of 150 patients with critically ill children who were hospitalized in our hospital from March 2014 to May 2018 were enrolled as the study subjects. According to the prognosis, they were divided into the survival group of 97 cases and the end point group of 53 cases. Differences in procalcitonin, lactate dehydrogenase, serum calcium, blood lactate, and blood pH levels.ResultsThere was no significant difference in age and gender between the two groups (P>0.05). Procalcitonin, lactate dehydrogenase and blood lactate in the survival group were(0.72±0.31) ng/ml, (75.43±28.88) IU/L and (4.71±1.88) mmol/L, respectively, which were lower than the endpointgroup (1.98±0.92) ng/ml, (119.2±49.89) IU/L and (8.46±2.98) mmol/L; the serum calcium and blood pH values were (1.41±0.55) mmol/L and (7.23±0.20), respectively, above the endpoint group (1.13 ± 0.42) mmol/L and(7.05±0.15), the difference was statistically significant(P<0.05). Conclusion For procalcitonin, lactate dehydrogenase, blood lactate, blood calcium and severe acidosis, the quality of life and prognosis are poor, and the risk of death increases. These clinical indicators have important clinical guiding significance for the prognosis of critically ill children with PICU.

参考文献/References:


[1]胡红玲,周霞,李映兰.儿童早期预警评分在识别危重患儿病情中的价值[J].中国当代儿科杂志,2018,20(8):658-662.
[2]曾健生.小儿病情危重程度评分[J].中华实用儿科临床杂志,2013,28(18):1364-1367.
[3]张晨美,叶盛.危重患儿热能与蛋白质供给充分性与预后关系[J].中国实用儿科杂志,2016,31(9):661-664.
[4]Max M.Taking a New Position on Mechanical Ventilation[J].Crit Care Med,2015,43(10):2268-2269.
[5]Shubhangi A,Singh P,Singh PM,et al.Procalcitonin in survivors and nonsurvivors of sepsis:systematic review and meta analysis[J].Shock,2015,43(3):212-221.
[6]胡方启,程贤高,丁丹,等.儿童脓毒症血培养结果与血清降钙素原关系分析[J].临床儿科杂志,2015,33(4):326-329.
[7]齐英征.降钙素原与小儿危重病例评分对脓毒症患儿预后的影响[J].中国当代儿科杂志,2014,16(2):190-193.
[8]索立华.低钙血症与危重症的相关性分析[D].宁夏医科大学,2014.
[9]任晓旭.脓毒性休克早期识别[J].中国实用儿科杂志,2017,32(6):417-422.
[10]中华医学会儿科学分会急救学组.儿童脓毒性休克(感染性休克)诊治专家共识(2015版)[J].中华儿科杂志,2015,53(8):576-580.
[11]Filho RR,Rocha LL,Correa TD,et al.Blood lactate levels cutoff and mortality prediction in sepsis-time for a reappraisal? A retrospective cohort study[J].Shock,2016,46(5):480-485.
[12]Gorgis N,Asselin JM,Fontana C,et al.Evaluation of the association of early elevated lactate with outcomes in children with severe sepsis or septic shock[J].Pediatr Emer Care,2017(9).
[13]Casserly B,Phillips GS,Schorr C,et al.Lactate measurements in sepsis-induced tissue hypoperfusion:results from the surviving sepsis campaign database[J].Crit Care Med,2015,43(3):567-573.

相似文献/References:

[1]张西园.糖尿病与结直肠癌患者预后相关研究进展[J].医学信息,2018,31(01):55.[doi:10.3969/j.issn.1006-1959.2018.01.020]
　ZHANG Xi-yuan.Research Progress in the Relationship between Diabetes and the Prognosis of Colorectal Cancer[J].Journal of Medical Information,2018,31(22):55.[doi:10.3969/j.issn.1006-1959.2018.01.020]
[2]张林.围术期输血对胃癌根治术患者预后及免疫的影响[J].医学信息,2018,31(01):94.[doi:10.3969/j.issn.1006-1959.2018.01.033]
　ZHANG Lin.Effect of Perioperative Blood Transfusion on Prognosis and Immunity of Patients with Radical Gastrectomy[J].Journal of Medical Information,2018,31(22):94.[doi:10.3969/j.issn.1006-1959.2018.01.033]
[3]及预后罗华.白内障术后眼内炎的危险因素分析[J].医学信息,2018,31(01):108.[doi:10.3969/j.issn.1006-1959.2018.01.040]
　LUO Hua.Risk Factors and Prognosis of Endophthalmitis after Cataract Surgery[J].Journal of Medical Information,2018,31(22):108.[doi:10.3969/j.issn.1006-1959.2018.01.040]
[4]李 轩,王子为,赵靖萱,等.肿瘤预后预测领域机器学习应用的文献计量与热点可视化分析[J].医学信息,2022,35(09):90.[doi:10.3969/j.issn.1006-1959.2022.09.023]
　LI Xuan,WANG Zi-wei,ZHAO Jing-xuan,et al.Visualization Analysis on Bibliometrics and Hot Spots of Machine Learning Applications in the Field of Tumor Prognosis Prediction[J].Journal of Medical Information,2022,35(22):90.[doi:10.3969/j.issn.1006-1959.2022.09.023]
[5]倪凤媛,李青山,刘兰芳,等.复发转移乳腺癌首发转移模式及预后影响因素[J].医学信息,2018,31(12):1.[doi:10.3969/j.issn.1006-1959.2018.12.001]
　NI Feng-yuan,LI Qing-shan,LIU Lan-fang,et al.The First Metastatic Model of Metastatic Breast Cancer and the Influencing Factors of its Prognosis[J].Journal of Medical Information,2018,31(22):1.[doi:10.3969/j.issn.1006-1959.2018.12.001]
[6]施雨南,陈志平,肖秋香,等.KAI1、Snail、Slug、E-cadherin在鼻咽癌中的表达及其与患者预后的关系[J].医学信息,2022,35(11):77.[doi:10.3969/j.issn.1006-1959.2022.11.021]
　SHI Yu-nan,CHEN Zhi-ping,XIAO Qiu-xiang,et al.The Expression of KAI1, Snail, Slug, and E-cadherin in Nasopharyngeal Carcinoma and its Relationship with the Prognosis of patients[J].Journal of Medical Information,2022,35(22):77.[doi:10.3969/j.issn.1006-1959.2022.11.021]
[7]王双英,张 娜,刘 芳.具有高危复发因素的早期宫颈癌术后辅助治疗进展[J].医学信息,2018,31(15):33.[doi:10.3969/j.issn.1006-1959.2018.15.012]
　WANG Shuang-ying,ZHANG Na,LIU Fang.Advances in Postoperative Adjuvant Therapy for Early Cervical Cancer with High Risk of Recurrence[J].Journal of Medical Information,2018,31(22):33.[doi:10.3969/j.issn.1006-1959.2018.15.012]
[8]李 光.替吉奥联合阿帕替尼治疗晚期胰腺癌的疗效分析[J].医学信息,2018,31(16):87.[doi:10.3969/j.issn.1006-1959.2018.16.025]
　LI Guang.Therapeutic Effect of Tiggio Combined with Apatinib in the Treatment of Advanced Pancreatic Cancer[J].Journal of Medical Information,2018,31(22):87.[doi:10.3969/j.issn.1006-1959.2018.16.025]
[9]田 明,常伟平.UbcH10在肝癌中的表达及其与预后的关系[J].医学信息,2019,32(12):77.[doi:10.3969/j.issn.1006-1959.2019.12.024]
　IAN Ming,CHANG Wei-ping.Expression of UbcH10 in Hepatocellular Carcinoma and Its Relationship with Prognosis[J].Journal of Medical Information,2019,32(22):77.[doi:10.3969/j.issn.1006-1959.2019.12.024]
[10]刘 锌,杜 斌,孙光权,等.血清岩藻糖苷酶在股骨头坏死保髋患者预后判断中的临床价值[J].医学信息,2018,31(19):64.[doi:10.3969/j.issn.1006-1959.2018.19.021]
　LIU Xin,DU Bin,SUN Guang-quan,et al.Clinical Value of Serum Fucosidase in Predicting the Prognosis of Hip Preservation patients with Osteonecrosis of Femoral Head[J].Journal of Medical Information,2018,31(22):64.[doi:10.3969/j.issn.1006-1959.2018.19.021]

更新日期/Last Update: 2018-12-03