[1]孟思博,赵 成.骨巨细胞瘤的治疗方案与并发症的相关性分析[J].医学信息,2018,31(24):167-169.[doi:10.3969/j.issn.1006-1959.2018.24.051]
　MENG Si-bo,ZHAO Cheng.Correlation Analysis between Treatment Plan and Complications of Giant Cell Tumor of Bone[J].Journal of Medical Information,2018,31(24):167-169.[doi:10.3969/j.issn.1006-1959.2018.24.051]
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骨巨细胞瘤的治疗方案与并发症的相关性分析()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
31卷
期数:
2018年24期
页码:
167-169
栏目:
出版日期:
2018-12-15

文章信息/Info

Title:
Correlation Analysis between Treatment Plan and Complications of Giant Cell Tumor of Bone
文章编号:
1006-1959（2018）24-0167-03
作者:
孟思博1; 赵 成2
1.山东大学齐鲁医院<青岛>化疗科，山东 青岛 266000；2.六盘水市人民医院骨一科，贵州 六盘水 553000
Author(s):
MENG Si-bo1; ZHAO Cheng2
1.Department of Chemotherapy,Qilu Hospitalof Shandong University,Qingdao 266000,Shandong,China;2.Department of Bone,Subject One,People's Hospital of Liupanshui City,Liupanshui 553000, Guizhou,China
关键词:
骨巨细胞瘤; 并发症; 相关因素
Keywords:
Giant cell tumor of bone; Complications; Related factors
分类号:
R738.1
DOI:
10.3969/j.issn.1006-1959.2018.24.051
文献标志码:
A
摘要:
目的 分析骨巨细胞瘤的治疗方案与并发症的相关性。方法 回顾性分析2005年1月~2013年12月于山东大学齐鲁医院进行骨巨细胞瘤手术治疗患者56例，记录患者年龄、性别、肿瘤发生部位、术后辅助治疗方案、术式及并发症发生率。结果 术后进行辅助治疗患者并发症发生率为43.48%，高于未进行辅助治疗患者的15.15%，差异有统计学意义（P＜0.05）；采用肿瘤切除+物理化学方法治疗患者并发症发生率为41.94%，高于单纯切除患者的0，差异有统计学意义（P＜0.05）；扩大切除组患者的并发症发生率为12.50%，低于单纯切除患者，高于切除+物理化学方法，差异均有统计学意义（P＜0.05）。结论 骨巨细胞瘤患者术后放疗或应用双膦酸盐类药物辅助治疗，采用肿瘤切除+物理化学方法及肿瘤扩大切除会增加患者术后并发症的发生率，因此应根据患者具体情况选择术式。
Abstract:
Objective To analyze the the correlation between treatment regimen and complications of complications of giant cell tumor of bone. Methods A retrospective analysis of 56 patients with giant cell tumor of the bone at Qilu Hospital of Shandong University from January 2005 to December 2013 was performed. The age, sex, tumor location, postoperative adjuvant treatment, surgery and complications were recorded. Incidence. Results The incidence of postoperative complication was 43.48%, which was higher than that of 15.15% of patients without adjuvant therapy. The difference was statistically significant (P<0.05).The incidence of complication was 41.94% in patients treated with tumor resection+physical chemistry, which was significantly higher than that in patients with simple resection (P<0.05). The complication rate in patients with enlarged resection was 12.50%, low. In patients with simple resection, the difference was statistically significant (P<0.05). Conclusion In patients with giant cell tumor of the bone, postoperative radiotherapy or bisphosphonate adjuvant therapy, tumor resection + physicochemical methods and enlarged tumor resection will increase the incidence of postoperative complications, so the choice should be based on the patient's specific conditions.

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更新日期/Last Update: 2019-01-09