[1]李雪芹,王存德,龚 泉,等.鸦胆子油乳注射液配合恩度治疗恶性胸腔积液的临床分析[J].医学信息,2018,31(03):13-15,20.[doi:10.3969/j.issn.1006-1959.2018.03.005]
　LI Xue-qin,WANG Cun-de,GONG Quan,et al.Clinical Analysis of Brucea Javanica Oil Emulsion Injection Combined with Endor in the Treatment of Malignant Pleural Effusion[J].Medical Information,2018,31(03):13-15,20.[doi:10.3969/j.issn.1006-1959.2018.03.005]
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鸦胆子油乳注射液配合恩度治疗恶性胸腔积液的临床分析()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
31卷
期数:
2018年03期
页码:
13-15,20
栏目:
出版日期:
2018-02-01

文章信息/Info

Title:
Clinical Analysis of Brucea Javanica Oil Emulsion Injection Combined with Endor in the Treatment of Malignant Pleural Effusion
文章编号:
1006-1959（2018）03-0013-04
作者:
李雪芹; 王存德; 龚 泉; 李仕娟; 陈 曦
云南省肿瘤医院/昆明医科大学第三附属医院姑息医学科/云南省肿瘤姑息医学研究中心，云南 昆明 650118
Author(s):
LI Xue-qin; WANG Cun-de; GONG Quan; LI Shi-juan; CHEN Xi
Yunnan Provincial Cancer Hospitall/Department of Palliative Medicine,Third Affiliated Hospital of Kunming Medical University/ Yunnan Provincial Research Center of Oncology and Palliative Medicine,Kunming 650118,Yunnan,China
关键词:
重组人血管内皮抑素/恩度; 鸦胆子油乳; 恶性胸腔积液
Keywords:
Recombinant human vascular endostatin/endor; Brucea javanica oil emulsion; Malignant pleural effusion
分类号:
R730.5
DOI:
10.3969/j.issn.1006-1959.2018.03.005
文献标志码:
A
摘要:
目的 探讨鸦胆子油乳注射液配合恩度治疗恶性胸腔积液的疗效、安全性及患者生活质量改善情况。方法 研究观察2013年7月~2016年7月住院的恶性胸腔积液患者41例，随机分为联合治疗组22例和恩度单药治疗组19例，分析两组患者在疗效、药物不良反应、生活质量方面的差异。结果 联合治疗组总有效率较单药治疗组提高（P＜0.05），不良反应轻，两组患者的生活质量均有所改善，且联合治疗组生活质量改善率较单药治疗组提高（P＜0.05）。结论 鸦胆子油乳注射液配合恩度治疗恶性胸腔积液疗效较恩度单药治疗略有提高，不良反应患者可耐受，能改善恶性胸腔积液患者的生活质量，具有一定的临床价值。
Abstract:
Objective To investigate the efficacy,safety and quality of life improvement of brucea javanica oil injection combined with endor in the treatment of malignant pleural effusion.Methods 41 patients with malignant pleural effusion who were hospitalized from July 2013 to July 2016 were randomly divided into two groups:combined treatment group(n=22)and endocrine single drug treatment group(n=19).The curative effect, adverse drug reaction,quality of life differences.Results The total effective rate in the combination therapy group was significantly higher than that in the monotherapy group(P<0.05),and the adverse reactions were mild. The quality of life of both groups was improved,and the improvement rate of the quality of life in the combination therapy group was higher than that in the monotherapy group(P<0.05).Conclusion Brucea javanica oil emulsion injection with endor treatment of malignant pleural effusion effect of single-agent treatment slightly better,patients with adverse reactions can be tolerated,can improve the quality of life of patients with malignant pleural effusion,has some clinical value.

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更新日期/Last Update: 2018-02-01