[1]唐彦慧,彭子春,唐 琪.Caspase-3在不同分期翼状胬肉上皮细胞中表达的研究[J].医学信息,2018,31(03):71-72.[doi:10.3969/j.issn.1006-1959.2018.03.022]
　TANG Yan-hui,PENG Zi-chun,TANG Qi.Study on the Expression of Caspase-3 in Pterygium Epithelial Cells in Different Stages[J].Journal of Medical Information,2018,31(03):71-72.[doi:10.3969/j.issn.1006-1959.2018.03.022]
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Caspase-3在不同分期翼状胬肉上皮细胞中表达的研究()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
31卷
期数:
2018年03期
页码:
71-72
栏目:
论著
出版日期:
2018-02-01

文章信息/Info

Title:
Study on the Expression of Caspase-3 in Pterygium Epithelial Cells in Different Stages
文章编号:
1006-1959（2018）03-0071-02
作者:
唐彦慧; 彭子春; 唐 琪
南宁市第一人民医院眼科，广西 南宁 530022
Author(s):
TANG Yan-hui; PENG Zi-chun; TANG Qi
Department of Ophthalmology,Nanning First People's Hospital,Nanning 530022,Guangxi,China
关键词:
Caspase-3; 翼状胬肉; 临床分期; 免疫组织化学
Keywords:
Caspase-3; Pterygium; Clinical staging; Immunohistochemistry
分类号:
R777.33
DOI:
10.3969/j.issn.1006-1959.2018.03.022
文献标志码:
A
摘要:
目的 探讨Caspase-3在不同临床分期的翼状胬肉中的表达和意义。方法 采用免疫组化Elibision法检测20例静止期翼状胬肉、20例活动期翼状胬肉、10例正常结膜中上皮细胞中Caspase-3的表达。结果 Caspase-3在翼状胬肉上皮细胞中为低表达，和正常对照组差异有统计学意义（P＜0.05），静止期和活动期翼状胬肉组间差异无统计学意义（P＞0.05）。结论 Caspase-3在翼状胬肉上皮细胞中为低表达，提示翼状胬肉的发生、发展有可能和上皮细胞凋亡和增殖异常有关。
Abstract:
Objective To investigate the expression and significance of Caspase-3 in pterygium at different clinical stages.Methods 20 cases of quiescent pterygium and 20 cases of active pterygium were detected by immunohistochemical Elibision method. Expression of Caspase-3 in epithelial cells of 10 cases of normal conjunctiva.Results The expression of Caspase-3 was low in pterygium epithelial cells.There was significant difference between pterygium group and normal control group(P<0.05),but there was no significant difference in pterygium between static and active stage(P>0.05).Conclusion The low expression of Caspase-3 in pterygium epithelial cells suggests that the occurrence and development of pterygium may be related to the abnormal apoptosis and proliferation of pterygium cells.

参考文献/References:

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更新日期/Last Update: 2018-02-01