[1]雷 敏.不孕不育患者解脲脲支原体培养及耐药性分析[J].医学信息,2018,31(06):156-157.[doi:10.3969/j.issn.1006-1959.2018.06.055]
　LEI Min.Analysis of Culture and Drug Resistance of Ureaplasma Urealyticum in Infertility Patients[J].Journal of Medical Information,2018,31(06):156-157.[doi:10.3969/j.issn.1006-1959.2018.06.055]
点击复制

不孕不育患者解脲脲支原体培养及耐药性分析()
分享到：

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
31卷
期数:
2018年06期
页码:
156-157
栏目:
诊疗技术
出版日期:
2018-03-20

文章信息/Info

Title:
Analysis of Culture and Drug Resistance of Ureaplasma Urealyticum in Infertility Patients
文章编号:
1006-1959（2018）06-0156-02
作者:
雷 敏
南华大学附属常德医院生殖中心，湖南 常德 415000
Author(s):
LEI Min
The Reproductive Center of Changde Hospital Affiliated to Nanhua University,Changde 415000,Hunan,China
关键词:
不孕不育; 解脲脲支原体; 耐药性
Keywords:
Key words：Infertility; Ureaplasma urealyticum; Drug resistance
分类号:
R711.6
DOI:
10.3969/j.issn.1006-1959.2018.06.055
文献标志码:
A
摘要:
目的 研究不孕不育患者解脲脲支原体感染及对药物的耐药性。方法 回顾分析2016年1月~2017年12月在南华大学附属常德医院诊治的94例不孕不育患者和40例已生育健康者的临床资料，对比两组解脲脲支原体感染情况。结果 不孕不育组男性、女性解脲脲支原体感染率分别为13例（30.95%）、21例（40.38%），高于对照组的2例（12.50%）、4（16.67%），差异有统计学意义（P<0.05）；94例不孕不育患者共检出68株解脲脲支原体，对解脲脲支原体培养，敏感性较高的为四环素、强力霉素、交沙霉素、美满霉素、克拉霉素、阿奇霉素，耐药性最高的是诺氟沙星。结论 不孕不育患者解脲脲支原体感染率较高可能是不孕不育的主要因素，临床可将其检测作为临床筛查的内容。同时治疗解脲脲支原体感染，应依据药敏试验结果选择敏感性高的抗生素，以提高临床治疗效果。
Abstract:
Abstract：Objective To study Ureaplasma urealyticum infection and drug resistance in infertility patients.Methods The clinical data of 94 infertile patients and 40 fertile healthy subjects treated in Changde Hospital affiliated to Nanhua University from January 2016 to December 2017 were retrospectively analyzed.The infection of Ureaplasma Urealyticum was compared between the two groups.Results Male and female infertility group infection of Ureaplasma urealyticum were 13 cases(30.95%),21 cases(40.38%),more than 2 cases of control group(12.50%),4(16.67%),the difference was statistically significant(P<0.05);94 cases of infertility patients were detected in 68 strains of Ureaplasma urealyticum and Ureaplasma culture urealyticum, high sensitivity to tetracycline,doxycycline, josamycin,minocycline,clarithromycin,azithromycin,the highest resistance to norfloxacin.Conclusion The high infection rate of Ureaplasma urealyticum in infertility patients may be the main factor of infertility,and clinical detection can be used as the content of clinical screening.At the same time,the treatment of Ureaplasma urealyticum infection should be based on drug sensitivity test results to select high-sensitivity antibiotics to improve clinical treatment.

参考文献/References:

[1]陈浩宇,郭海波,吴晓蔓,等.2744例泌尿生殖道感染患者解脲支原体和人型支原体分布及耐药性分析[J].中华实用诊断与治疗杂志,2016,30(4):415-416. [2]王萍,魏云.不孕不育患者生殖道分泌物支原体培养及药敏结果分析[J].标记免疫分析与临床,2013,20(5):303-305. [3]叶聪秀,尹颂超,易金玲,等.8375例泌尿生殖道支原体感染状况及耐药性分析[J].热带医学杂志,2012,12(10):1226-1227. [4]崔英丽,蔡知天,李楷滨,等.解脲支原体在不孕不育及不良妊娠结局的作用[J].中国妇幼保健,2012, 27(6):944-946. [5]龙彩云,凌彩铃,区旭春.3558例患者泌尿生殖道衣原体支原体检测及耐药性分析[J].实用医学杂志,2015,31(23):3921-3922. [6]史云峰,车志伟,赵牧秋.脲酶抑制剂NBPT提前施用对尿素水解和氨挥发的影响[J].环境保护科学,2016,42(5):107-111. [7]张俏忻.男性不育人群不同生物群解脲支原体对精子质量的影响及其机制研究[D].南方医科大学,2014. [8]张月红,陆建红,陈国军,等.女性生殖道491株解脲脲支原体药敏结果分析[J].中华医院感染学杂志,2013,23(19):4860-4860.

相似文献/References:

[1]杨英杰,谈 笑.解脲脲原体感染研究进展[J].医学信息,2018,31(03):61.[doi:10.3969/j.issn.1006-1959.2018.03.019]
　YANG Ying-jie,TAN Xiao.Advances in Ureaplasma Urealyticum Infection[J].Journal of Medical Information,2018,31(06):61.[doi:10.3969/j.issn.1006-1959.2018.03.019]
[2]王立琦,季则明,于建英.女性不孕不育应用宫腔镜下输卵管插管通液治疗的效果分析[J].医学信息,2018,31(05):116.[doi:10.3969/j.issn.1006-1959.2018.05.040]
　WANG Li-qi,JI Ze-ming,YU Jian-ying.Analysis of the Effect of Hysteroscopic Tubal Intubation in the Treatment of Female Infertility[J].Journal of Medical Information,2018,31(06):116.[doi:10.3969/j.issn.1006-1959.2018.05.040]
[3]范叶柏,王 众,杨晓晨.血清激素联合免疫抗体在不孕不育筛查预防中的应用价值[J].医学信息,2021,34(04):174.[doi:10.3969/j.issn.1006-1959.2021.04.048]
　FAN Ye-bai,WANG Zhong,YANG Xiao-chen.Application Value of Serum Hormone Combined Immune Antibody in Infertility Screening and Prevention[J].Journal of Medical Information,2021,34(06):174.[doi:10.3969/j.issn.1006-1959.2021.04.048]

更新日期/Last Update: 2018-03-15