[1]张 黎.中晚期原发性肝癌介入治疗的临床效果及对 肝功能的影响[J].医学信息,2018,31(09):20-22.[doi:10.3969/j.issn.1006-1959.2018.09.006]
 ZHANG Li.The Clinical Effect of Interventional Treatment of Primary Liver Cancer in Middle and Late Stage and its Effect on Liver Function[J].Journal of Medical Information,2018,31(09):20-22.[doi:10.3969/j.issn.1006-1959.2018.09.006]
点击复制

中晚期原发性肝癌介入治疗的临床效果及对 肝功能的影响()
分享到:

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
31卷
期数:
2018年09期
页码:
20-22
栏目:
出版日期:
2018-05-01

文章信息/Info

Title:
The Clinical Effect of Interventional Treatment of Primary Liver Cancer in Middle and Late Stage and its Effect on Liver Function
文章编号:
1006-1959(2018)09-0020-03
作者:
张 黎
桂林市中西医结合医院肿瘤科,广西 桂林 541004
Author(s):
ZHANG Li
Department of Oncology,Guilin Hospital of Integrated Traditional Chinese and Western Medicine,Guilin 541004,Guangxi,China
关键词:
原发性肝癌肝癌介入治疗术临床疗效肝功能
Keywords:
Key words:Primary liver cancerLiver cancer interventional therapyClinical efficacyLiver function
分类号:
R735.7
DOI:
10.3969/j.issn.1006-1959.2018.09.006
文献标志码:
A
摘要:
目的 探讨中晚期原发性肝癌介入治疗的临床效果及对肝功能的影响。方法 选取2015年11月~2017年10月我院收治的46例中晚期原发性肝癌患者为研究对象,全部患者均接受肝癌介入治疗,观察患者的治疗效果及治疗前后肝脏功能变化。结果 46例患者介入治疗1次后完全缓解14例,治疗2次后完全缓解27例,差异有统计学意义(P<0.05);46例患者行介入治疗后,肝脏谷丙转氨酶(ALT)、甲胎蛋白(AFP)和总胆红素(TBIL)水平低于治疗前,白蛋白水平高于治疗前,差异均有统计学意义(P<0.05)。结论 肝癌介入手术可有效治疗中晚期原发性肝癌,值得在临床上进一步推广应用。
Abstract:
Abstract:Objective To investigate the clinical effect of interventional treatment of primary liver cancer in middle and late stage and its effect on liver function.Methods A total of 46 patients with advanced hepatocellular carcinoma who were admitted to our hospital from November 2015 to October 2017 were selected as the study subjects.All patients received interventional treatment of liver cancer.The therapeutic effect and changes of liver function before and after treatment were observed.Results Complete remission was achieved in 14 patients after interventional therapy for one time in 46 patients and complete remission in 27 patients after two treatment visits,the difference was statistically significant(P<0.05);after interventional treatment in 46 patients,liver alanine aminotransferase(ALT),alpha-fetoprotein(AFP)and total bilirubin(TBIL)levels were lower than before treatment,albumin levels before treatment,the difference was statistically significant(P<0.05).Conclusion Liver cancer interventional treatment can effectively treat advanced primary liver cancer.It is worth further promotion and application in clinical practice.

参考文献/References:

[1]李焱,程朋.中晚期肝癌临床治疗进展[J].临床肝胆病杂志,2014,30(3):233-236.
[2]杨柏帅,施裕新,袁敏,等.TACE治疗既往有肝功能衰竭史肝癌患者七例[J].介入放射学杂志,2014,23(9):805-808.
[3]杨秉辉,任正刚.原发性肝癌诊断标准[J].中华肝脏病杂志,2000,8(3):135.
[4]杨树法,黄伍奎,王海林.肝动脉化疗栓塞联合射频消融术治疗30例原发性大肝癌的疗效评价[J].介入放射学杂志,2012,21(4):322-326.
[5]柯群刚,黄继超,刘细国,等.导管肝动脉化疗栓塞治疗中晚期肝癌对患者肝脏功能的影响[J].中华普外科手术学杂志(电子版),2015,12(5):33-35.
[6]康朔麟,饶智国,王志刚.以肝动脉化疗栓塞术为主综合治疗中晚期肝癌的研究进展[J].临床误诊误治,2014,27(4):107-110.
[7]冯超,赵剑波,陈勇,等.原发性肝癌切除术后预防性经肝动脉介入治疗:肝动脉化疗栓塞术和化疗灌注术比较[J].介入放射学杂志,2014,23(8):679-682.
[8]顾朋,黄伍奎,刘墨,等.海藻酸钠栓塞对原发性肝癌介入治疗早期肝功能损伤及并发症的影响[J].中国实用医药,2017,12(1):14-16.
[9]皮儒先,伍强,徐小玲,等.肝癌介入治疗后调整肠道菌群对肝功能及内毒素的影响作用[J].实用肿瘤杂志,2014,29(5):454-456.
[10]王赫,周毅,刘玉荣.三种保肝药治疗中晚期肝癌介入化疗栓塞后肝损伤的疗效比较[J].航空航天医学杂志,2016,4(1):1-3.

相似文献/References:

[1]朱 瑞.血清AFP、CA19-9、CEA单项及三者联合检验对原发性肝癌早期诊断与治疗的意义对比[J].医学信息,2018,31(13):154.[doi:10.3969/j.issn.1006-1959.2018.13.047]
 ZHU Rui.Comparison of the Significance of Serum AFP,CA19-9,CEA Single and Combined the Three Methods Tests in the Early Diagnosis and Treatment of Primary Liver Cancer[J].Journal of Medical Information,2018,31(09):154.[doi:10.3969/j.issn.1006-1959.2018.13.047]
[2]侯宝松,王海峰,徐海晶,等.大黄蛰虫方合逍遥方加减对原发性肝细胞癌 TACE术后综合征影响[J].医学信息,2018,31(14):53.[doi:10.3969/j.issn.1006-1959.2018.14.017]
 HOU Bao-song,WANG Hai-feng,XU Hai-jing,et al.Effect of Rhubarb Aphid Fanghe Xiaoyaofang Decoction on Postoperative TACE Syndrome of Primary Hepatocellular Carcinoma[J].Journal of Medical Information,2018,31(09):53.[doi:10.3969/j.issn.1006-1959.2018.14.017]
[3]郑德仁.多排螺旋CT诊断肝血管瘤及肝脏肿瘤的临床价值分析[J].医学信息,2018,31(20):160.[doi:10.3969/j.issn.1006-1959.2018.20.050]
 ZHENG De-ren.Clinical Value of Multi-slice Spiral CT in Diagnosis of Hepatic Hemangioma and Liver Tumor[J].Journal of Medical Information,2018,31(09):160.[doi:10.3969/j.issn.1006-1959.2018.20.050]
[4]赵鱼扉,史政荣.肝脏储备功能临床应用研究[J].医学信息,2019,32(10):35.[doi:10.3969/j.issn.1006-1959.2019.10.013]
 ZHAO Yu-fei,SHI Zheng-rong.Clinical Application of Liver Reserve Function[J].Journal of Medical Information,2019,32(09):35.[doi:10.3969/j.issn.1006-1959.2019.10.013]
[5]姜天奇,张洪亮.原发性肝癌的中西医治疗现状[J].医学信息,2019,32(13):35.[doi:10.3969/j.issn.1006-1959.2019.13.012]
 JIANG Tian-qi,ZHANG Hong-liang.Current Status of Treatment of Primary Liver Cancer with Traditional Chinese Medicine and Western Medicine[J].Journal of Medical Information,2019,32(09):35.[doi:10.3969/j.issn.1006-1959.2019.13.012]
[6]邢时龙,淦 勤.原发性肝癌患者血清25-羟基维生素D3水平与免疫抑制因子IL-10的关系[J].医学信息,2020,33(01):101.[doi:10.3969/j.issn.1006-1959.2020.01.030]
 XING Shi-long,GAN Qin.Relationship Between Serum 25-hydroxyvitamin D3 Level and Immunosuppressive Factor IL-10 in Patients with Primary Liver Cancer[J].Journal of Medical Information,2020,33(09):101.[doi:10.3969/j.issn.1006-1959.2020.01.030]
[7]王瑞航,姚升娟,张 晨,等.肝动脉化疗栓塞介入术对原发性肝癌患者近期疗效及Child-Pugh分级的影响[J].医学信息,2020,33(17):101.[doi:10.3969/j.issn.1006-1959.2020.17.029]
 WANG Rui-hang,YAO Sheng-juan,ZHANG Chen,et al.Effect of Interventional Hepatic Artery Chemoembolization on the Short-term Efficacy and Child-Pugh Classification of Patients with Primary Liver Cancer[J].Journal of Medical Information,2020,33(09):101.[doi:10.3969/j.issn.1006-1959.2020.17.029]
[8]郑澹宁,孙国平.肝动脉化疗栓塞的肝癌患者生活质量调查研究[J].医学信息,2020,33(22):127.[doi:10.3969/j.issn.1006-1959.2020.22.036]
 ZHENG Dan-ning,SUN Guo-ping.Survey on the Quality of Life of Hepatocellular Cancer Patients Undergoing Transcatheter Arterial Chemoembolization[J].Journal of Medical Information,2020,33(09):127.[doi:10.3969/j.issn.1006-1959.2020.22.036]
[9]包学智.经肝动脉化疗栓塞联合射频消融术治疗中晚期原发性肝癌的效果[J].医学信息,2020,33(19):110.[doi:10.3969/j.issn.1006-1959.2020.19.033]
 BAO Xue-zhi.The Effect of Transhepatic Artery Chemoembolization Combined with Radiofrequency Ablation in the Treatment of Advanced Primary Liver Cancer[J].Journal of Medical Information,2020,33(09):110.[doi:10.3969/j.issn.1006-1959.2020.19.033]
[10]郑春榕,阮清发.康氏学术流派在原发性肝癌治疗中的经验拾萃[J].医学信息,2021,34(05):169.[doi:10.3969/j.issn.1006-1959.2021.05.049]

更新日期/Last Update: 2018-05-01