[1]邹 鑫,刘秀娟,余燕燕.血液透析对MHD患者血清FGF-23水平与 钙磷代谢的影响[J].医学信息,2018,31(09):119-120.[doi:10.3969/j.issn.1006-1959.2018.09.036]
　ZOU Xin,LIU Xiu-juan,YU Yan-yan.Effect of Hemodialysis on Serum FGF-23 Level and Calcium and Phosphorus Metabolism in MHD Patients[J].Journal of Medical Information,2018,31(09):119-120.[doi:10.3969/j.issn.1006-1959.2018.09.036]
点击复制

血液透析对MHD患者血清FGF-23水平与 钙磷代谢的影响()
分享到：

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
31卷
期数:
2018年09期
页码:
119-120
栏目:
临床研究
出版日期:
2018-05-01

文章信息/Info

Title:
Effect of Hemodialysis on Serum FGF-23 Level and Calcium and Phosphorus Metabolism in MHD Patients
文章编号:
1006-1959（2018）09-0119-02
作者:
邹 鑫; 刘秀娟; 余燕燕
解放军第九四医院肾内科，江西 南昌 330000
Author(s):
ZOU Xin; LIU Xiu-juan; YU Yan-yan
Department of Renal Medicine,94th PLA Hospital,Nanchang 330000,Jiangxi,China
关键词:
血液透析; FGF-23; 钙磷代谢
Keywords:
Key words：Hemodialysis; FGF-23; Calcium and phosphorus metabolism
分类号:
R692.5
DOI:
10.3969/j.issn.1006-1959.2018.09.036
文献标志码:
A
摘要:
目的 观察血液透析对维持性血液透析患者外周血FGF-23水平与钙磷代谢的影响，为慢性肾衰患者调节钙磷水平提供参考。方法 选取2016年6月~2017年6月在本院经低钙透析液行MHD治疗患者35例，于治疗前、治疗1、3、6个月后取血检测患者血清FGF-23及钙磷水平。结果 MHD患者血清FGF-23与磷水平逐渐降低且低于治疗前水平，差异有统计学意义（P＜0.05）；血钙水平治疗1个月时与治疗前无显著性差异，治疗3个月后开始降低，差异有统计学意义（P＜0.05）。结论 血液透析能降低MHD患者血液FGF-23水平及钙、磷水平，且对于血清FGF-23与磷水平的调节作用更快，可作为慢性肾衰患者钙磷调节的有效方法。
Abstract:
Abstract：Objective To observe the effect of hemodialysis on peripheral blood FGF-23 levels and calcium and phosphorus metabolism in maintenance hemodialysis patients,and provide reference for the regulation of calcium and phosphorus levels in patients with chronic renal failure.Methods 35 patients with MHD treated with low calcium dialysate in our hospital from June 2016 to June 2017 were selected.Serum FGF-23 and calcium and phosphorus level were measured before 1,3 and 6 months after treatment.Results The levels of serum FGF-23 and phosphorus in MHD patients decreased gradually and were lower than those before treatment,the difference was statistically significant(P<0.05);There was no significant difference in serum calcium levels between 1 month and before treatment,and it began to decrease after 3 months of treatment,the difference was statistically significant(P<0.05). Conclusion Hemodialysis can reduce the blood FGF-23 levels and calcium and phosphorus levels in patients with MHD,and has a faster regulation effect on serum FGF-23 and phosphorus levels,and can be used as an effective method for calcium and phosphorus regulation in patients with chronic renal failure.

参考文献/References:

[1]朱金荣,张枫,张晓宇,等.血液透析患者钙磷代谢紊乱现状及影响因素分析[J].中国血液净化,2015,14(08):478-481.
[2]朱颖辉,李国刚.慢性肾脏病患者血清成纤维细胞生长因子23与肾功能及钙磷代谢的关系[J].临床荟萃, 2016,31(03):299-302.
[3]Shi Y,Zhao Y,Liu J,et al.Educational intervention for metabolic bone disease in patients with chronic kidney disease:a systematic review and meta-analysis[J].J Ren Nutr,2014,24(6):371-384.
[4]张俊,王倩,黄新忠.四种血液净化方式对尿毒症患者甲状旁腺激素、FGF23、钙磷及炎症因子的影响[J].南通大学学报(医学版),2017,37(04):315-318.
[5]张席军,安文军,周淑娟.慢性肾脏病患者外周血FGF-23水平与钙磷代谢的相关性分析[J]. 湖南师范大学学报(医学版),2016,13(04):52-54.
[6]Harjes LM,Parker VJ,Dembek K,et al.Fibroblast Growth Factor-23 Concentration in Dogs with Chronic Kidney Disease[J].J Vet Intern Med,2017,31(3):784-790.

相似文献/References:

[1]肖一红.组合型人工肾技术预防血液透析中低血压的效果观察[J].医学信息,2018,31(03):185.[doi:10.3969/j.issn.1006-1959.2018.03.070]
　XIAO Yi-hong.Effect of Combined Artificial Renal Technique in Preventing Hypotension in Hemodialysis[J].Journal of Medical Information,2018,31(09):185.[doi:10.3969/j.issn.1006-1959.2018.03.070]
[2]方海东,李 荣.血液透析滤过联合血液透析治疗慢性肾功能衰竭的效果观察[J].医学信息,2019,32(02):129.[doi:10.3969/j.issn.1006-1959.2019.02.037]
　FANG Hai-dong,LI Rong.Effect of Hemodiafiltration Combined with Hemodialysis on Chronic Renal Failure[J].Journal of Medical Information,2019,32(09):129.[doi:10.3969/j.issn.1006-1959.2019.02.037]
[3]蒋红利,刘 华,史珂慧,等.陕西省县级医院透析室建设项目培训效果评价[J].医学信息,2018,31(19):120.[doi:10.3969/j.issn.1006-1959.2018.19.036]
　JIANG Hong-li,LIU Hua,SHI Ke-hui,et al.Evaluation on Training Effect of Dialysis Room Construction Project in County Hospitals in Shaanxi Province[J].Journal of Medical Information,2018,31(09):120.[doi:10.3969/j.issn.1006-1959.2018.19.036]
[4]张民霞.血液灌流联合血液透析治疗肾功能衰竭难治性高血压的效果[J].医学信息,2019,32(15):109.[doi:10.3969/j.issn.1006-1959.2019.15.035]
　ZHANG Min-xia.Effect of Hemoperfusion Combined with Hemodialysis on Refractory Hypertension with Renal Failure[J].Journal of Medical Information,2019,32(09):109.[doi:10.3969/j.issn.1006-1959.2019.15.035]
[5]谢 华,周毅峰,甘晓庆,等.血液透析专用中心静脉导管封管液的研究[J].医学信息,2019,32(18):48.[doi:10.3969/j.issn.1006-1959.2019.18.016]
　XIE Hua,ZHOU Yi-feng,GAN Xiao-qing,et al.Research on Central Venous Catheter Sealing Fluid for Hemodialysis[J].Journal of Medical Information,2019,32(09):48.[doi:10.3969/j.issn.1006-1959.2019.18.016]
[6]喻学娜.协同护理对终末期肾脏病血液透析患者自我护理能力及治疗依从性的影响[J].医学信息,2019,32(20):183.[doi:10.3969/j.issn.1006-1959.2019.20.059]
　YU Xue-na.Effect of Collaborative Nursing on Self-care Ability and Treatment Compliance of Hemodialysis Patients with End-stage Renal Disease[J].Journal of Medical Information,2019,32(09):183.[doi:10.3969/j.issn.1006-1959.2019.20.059]
[7]魏昌林.血液透析联合血液灌流在终末期肾病患者治疗中的应用[J].医学信息,2019,32(13):109.[doi:10.3969/j.issn.1006-1959.2019.13.032]
　WEI Chang-lin.Application of Hemodialysis Combined with Blood Perfusion in the Treatment of Patients with End-stage Renal Disease[J].Journal of Medical Information,2019,32(09):109.[doi:10.3969/j.issn.1006-1959.2019.13.032]
[8]王艳霞.中药灌肠对尿毒症血液透析患者便秘、食欲减退及呕吐等不良反应的影响[J].医学信息,2022,35(17):88.[doi:10.3969/j.issn.1006-1959.2022.17.023]
　WANG Yan-xia.Effect of Traditional Chinese Herb Enema on Adverse Reactions of Constipation,Loss of Appetite and Vomiting in Uremic Hemodialysis Patients[J].Journal of Medical Information,2022,35(09):88.[doi:10.3969/j.issn.1006-1959.2022.17.023]
[9]钟瑜辉.血液透析联合血液灌流治疗尿毒症的效果[J].医学信息,2019,32(21):108.[doi:10.3969/j.issn.1006-1959.2019.21.034]
　ZHONG Yu-hui.Effect of Hemodialysis Combined with Blood Perfusion on Uremia[J].Journal of Medical Information,2019,32(09):108.[doi:10.3969/j.issn.1006-1959.2019.21.034]
[10]崔秀莉.心理护理对肾移植失功血液透析患者负性情绪及生活质量的影响[J].医学信息,2019,32(24):182.[doi:10.3969/j.issn.1006-1959.2019.24.068]
　CUI Xiu-li.Effect of Psychological Nursing on Negative Emotion and Quality of Life in Patients with Renal Transplantation Failure Hemodialysis[J].Journal of Medical Information,2019,32(09):182.[doi:10.3969/j.issn.1006-1959.2019.24.068]
[11]王允彦.西那卡塞对维持性血液透析继发性甲状旁腺功能亢进患者FGF-23的影响[J].医学信息,2018,31(13):88.[doi:10.3969/j.issn.1006-1959.2018.13.025]
　WANG Yun-yan.Effect of Cinacalcet on FGF-23 in Patients with Secondary Hyperparathyroidism during Maintenance Hemodialysis[J].Journal of Medical Information,2018,31(09):88.[doi:10.3969/j.issn.1006-1959.2018.13.025]

更新日期/Last Update: 2018-05-01