[1]尹静华.孟鲁司特钠治疗小儿哮喘的临床有效性分析[J].医学信息,2018,31(09):138-139.[doi:10.3969/j.issn.1006-1959.2018.09.043]
　YIN Jing-hua.Clinical Efficacy of Montelukast Sodium in Children with Asthma[J].Journal of Medical Information,2018,31(09):138-139.[doi:10.3969/j.issn.1006-1959.2018.09.043]
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孟鲁司特钠治疗小儿哮喘的临床有效性分析()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
31卷
期数:
2018年09期
页码:
138-139
栏目:
药物与临床
出版日期:
2018-05-01

文章信息/Info

Title:
Clinical Efficacy of Montelukast Sodium in Children with Asthma
文章编号:
1006-1959（2018）09-0138-02
作者:
尹静华
重庆市丰都县中医院儿科，重庆 408200
Author(s):
YIN Jing-hua
Department of Pediatrics,Fengdu County Hospital of Traditional Chinese Medicine,Chongqing 408200,China
关键词:
孟鲁司特钠; 小儿哮喘; 肺功能指标
Keywords:
Key words：Montelukast sodium; Children with asthma; Lung function index
分类号:
R725.6
DOI:
10.3969/j.issn.1006-1959.2018.09.043
文献标志码:
A
摘要:
目的 研究孟鲁司特钠治疗小儿哮喘的临床有效性。方法 选取2016年10月~2017年11月在我院治疗的120例小儿哮喘，随机分为对照组和观察组，各60例。对照组采用常规对症治疗，观察组采用孟鲁司特钠治疗，对比两组治疗有效率、临床症状消退时间、肺功能指标及不良反应情况。结果 观察组治疗有效率为96.67%，高于对照组的78.33%，差异有统计学意义（P＜0.05）。观察组咳嗽、肺部哮鸣音、憋喘消失时间均短于对照组，差异有统计学意义（P＜0.05）。观察组VCmax、FEV1、FEV1/FVC改善优于对照组，差异有统计学意义（P＜0.05）。在治疗和观察期间，两组患儿均未发生严重不良反应。结论 孟鲁司特钠治疗小儿哮喘疗效显著，可缩短患儿临床症状消退时间，改善患儿肺功能，值得临床推广和应用。
Abstract:
Abstract：Objective To study the clinical efficacy of montelukast sodium in treating asthma in children.Methods 120 children with asthma treated in our hospital from October 2016 to November 2017 were randomly divided into control group and observation group, 60 cases each.The control group was treated with routine symptomatic treatment.The observation group was treated with montelukast sodium.The efficacy of the two groups was compared, the clinical symptoms disappeared,the lung function indicators and adverse reactions were compared.Results The effective rate was 96.67% in the observation group,which was 78.33% higher than that in the control group,the difference was statistically significant(P<0.05).The cough in the observation group, the wheezing of the lungs,and the disappearance of asthma were all shorter than those in the control group,the difference was statistically significant(P<0.05).The observation group VCmax,FEV1,FEV1/FVC improved better than the control group,the difference was statistically significant(P<0.05). During the treatment and observation period,no serious adverse reactions occurred in both groups of children.Conclusion Montelukast sodium is effective in the treatment of children with asthma.It can shorten the time of clinical symptoms and improve the lung function of children.It is worthy of clinical promotion and application.

参考文献/References:

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更新日期/Last Update: 2018-05-01