[1]方海东,李 荣.血液透析滤过联合血液透析治疗慢性肾功能衰竭的效果观察[J].医学信息,2019,32(02):129-131.[doi:10.3969/j.issn.1006-1959.2019.02.037]
　FANG Hai-dong,LI Rong.Effect of Hemodiafiltration Combined with Hemodialysis on Chronic Renal Failure[J].Journal of Medical Information,2019,32(02):129-131.[doi:10.3969/j.issn.1006-1959.2019.02.037]
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血液透析滤过联合血液透析治疗慢性肾功能衰竭的效果观察()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
32卷
期数:
2019年02期
页码:
129-131
栏目:
临床研究
出版日期:
2019-01-15

文章信息/Info

Title:
Effect of Hemodiafiltration Combined with Hemodialysis on Chronic Renal Failure
文章编号:
1006-1959（2019）02-0129-03
作者:
方海东; 李 荣
1.天津医科大学第二医院肾内科，天津 300211；2.天津北大医疗海洋石油医院内分泌肾科，天津 300452
Author(s):
FANG Hai-dong; LI Rong
1.Department of Nephrology,the Second Hospital of Tianjin Medical University,Tianjin 300211, China;2.Department of Endocrinology and Kidney,Tianjin Peking University Medical Offshore Oil Hospital, Tianjin 300452,China
关键词:
血液透析; 慢性肾功能衰竭; 炎症因子; 肾功能
Keywords:
Hemodialysis; Chronic renal failure; Inflammatory factors; Renal function
分类号:
R692.5
DOI:
10.3969/j.issn.1006-1959.2019.02.037
文献标志码:
A
摘要:
目的 观察血液透析滤过联合血液透析治疗慢性肾衰的效果。方法 选择2017年6月~2018年6月在天津北大医疗海洋石油医院接受治疗的慢性肾功能衰竭患者70例，随机分为对照组和观察组，各35例。对照组仅接受血液透析治疗，观察组在此基础上加用血液透析滤过治疗。观察两组治疗前后血尿素氮（BUN）、血清肌酐（SCr）与肾小球过滤（GFR）变化水平，记录两组患者白细胞介素-8（IL-8）、白细胞介素-6（IL-6）与血清超敏C反应蛋白（hs-CRP）水平。结果 治疗后，观察患者BUN（6.07±1.31）mmo
Abstract:
Objective To observe the effect of hemodiafiltration combined with hemodialysis on chronic renal failure.Methods 70 patients with chronic renal failure who were treated at Tianjin Beida Medical Offshore Oil Hospital from June 2017 to June 2018 were randomly divided into control group and observation group, 35 cases each. The control group received only hemodialysis treatment, and the observation group was treated with hemodiafiltration. The levels of blood urea nitrogen (BUN), serum creatinine (SCr) and glomerular filtration (GFR) were observed before and after treatment. The two groups were recorded for interleukin-8 (IL-8) and interleukin-6 (IL-6) Serum hypersensitive C-reactive protein (hs-CRP) levels. Results After treatment, patients with BUN (6.07±1.31) mmol/L, SCr (117.09±10.99) μmol/L and GFR (121.49±12.25) ml/min were lower than the control group (8.36±1.24) mmol/L, (235.57±10.76) μmol/L, (140.83±12.18) ml/min, the difference was statistically significant (P<0.05); the IL-8, IL-6 and hs-CRP levels in the observation group were lower than the control group, the difference statistically significant (P<0.05). Conclusion Combined use of hemodiafiltration and hemodialysis in the treatment of patients with chronic renal failure can help remove harmful substances in the blood of patients to improve renal function, reduce the body's inflammatory response, and improve the clinical symptoms of patients.

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更新日期/Last Update: 2019-02-15