[1]邱亚双.辛夷鼻炎丸联合布地奈德治疗变应性鼻炎的临床观察[J].医学信息,2019,32(03):158-159.[doi:10.3969/j.issn.1006-1959.2019.03.052]
　QIU Ya-shuang.Clinical Observation of Xinyi Biyan Wan Combined with Budesonide in Treating Allergic Rhinitis[J].Journal of Medical Information,2019,32(03):158-159.[doi:10.3969/j.issn.1006-1959.2019.03.052]
点击复制

辛夷鼻炎丸联合布地奈德治疗变应性鼻炎的临床观察()
分享到：

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
32卷
期数:
2019年03期
页码:
158-159
栏目:
药物与临床
出版日期:
2019-02-01

文章信息/Info

Title:
Clinical Observation of Xinyi Biyan Wan Combined with Budesonide in Treating Allergic Rhinitis
文章编号:
1006-1959（2019）03-0158-02
作者:
邱亚双
（天津市滨海新区大港医院耳鼻喉科，天津 300000）
Author(s):
QIU Ya-shuang
(Department of Otorhinolaryngology,Dagang Hospital,Binhai New Area,Tianjin 300000,China)
关键词:
辛夷鼻炎丸; 布地奈德; 变应性鼻炎; IgE; LTE4
Keywords:
Xinyi Biyan Wan; Budesonide; Allergic rhinitis; IgE; LTE4
分类号:
R765.21
DOI:
10.3969/j.issn.1006-1959.2019.03.052
文献标志码:
A
摘要:
目的 分析辛夷鼻炎丸与布地奈德联合治疗变应性鼻炎的临床效果。方法 选取我院收治的112例变应性鼻炎患者，随机法分成对照组和观察组，各56例。对照组应用布地奈德治疗，观察组在此基础上加用辛夷鼻炎丸治疗，比较两组临床疗效、患者血清IgE水平、LTE4含量及用药不良反应。结果 观察组总有效率为85.71%，高于对照组的75.00%，差异有统计学意义（P＜0.05）；治疗4周观察组患者血清LTE4含量、IgE水平均低于对照组，差异有统计学意义（P＜0.05）；观察组不良反应发生率为5.36%，低于对照组的12.50%，但差异无统计学意义（P＞0.05）。结论 辛夷鼻炎丸与布地奈德联合治疗变应性鼻炎的临床效果显著，可改善患者血清IgE水平、LTE4含量，安全性较好。
Abstract:
Objective To analyze the clinical effect of Xinyi Biyan Wan combined with budesonide in the treatment of allergic rhinitis.Methods 112 patients with allergic rhinitis admitted to our hospital were randomly divided into control group and observation group, 56 cases each. The control group was treated with budesonide. The observation group was treated with Xinyi Biyan Wan. The clinical efficacy, serum IgE level, LTE4 content and adverse drug reactions were compared between the two groups.Results The total effective rate of the observation group was 85.71%, which was higher than that of the control group 75.00%,the difference was statistically significant (P<0.05).In the 4 weeks of treatment, the serum LTE4 content and IgE level of the observation group were lower than those of the control group,the difference was statistically significant (P<0.05). The incidence of adverse reactions in the observation group was 5.36%, which was lower than that in the control group (12.50%), but the difference was not statistically significant (P>0.05).Conclusion The clinical effect of Xinyi Biyan Wan combined with budesonide in the treatment of allergic rhinitis is significant, which can improve the serum IgE level and LTE4 content, and the safety is better.

参考文献/References:


[1]晋舒,宋敏.辛夷鼻炎丸联合布地奈德治疗变应性鼻炎的疗效及其对相关炎症因子的影响[J].中国药房,2017,28(18):2483-2485.
[2]钟泗华.辛夷鼻炎丸治疗变应性鼻炎60例临床观察[J].中国民族民间医药,2015,24(4):55.
[3]Lin WY,Muo CH,Ku YC,et al.Increased association between febrile convulsion and allergic rhinitis in children: A nationwide population-based retrospective cohort study[J].Pediatric neurology,2014,50(4):329-333.
[4]张静,孟令民.孟鲁司特钠联合布地奈德鼻喷剂治疗变应性鼻炎的疗效及对患者血清炎性因子的影响[J].重庆医学,2014,43(23):3065-3067.
[5]蔡建良,官树雄,麦周生,等.变应性及非变应性鼻炎患者白细胞介素-16、17的表达及意义[J].广东医学,2014(9):1395-1397.
[6]王静,付亚南,向莉,等.多重致敏因素的支气管哮喘和变应性鼻炎患儿特异性免疫球蛋白E的分布特征及临床意义[J].中华实用儿科临床杂志,2013,28(16):1216-1220.
[7]Lee HM,Park MS,Park IH,et al.A comparative pilot study of symptom improvement before and after phototherapy in Korean patients with perennial allergic rhinitis[J].Photochemistry and Photobiology: An International Journal,2013,89(3):751-757.
[8]王东安,孙洁民,杨硕,等.酮替芬联合舒利迭治疗哮喘合并变应性鼻炎的疗效观察[J].重庆医学,2013,42(16):1824-1825,1827.

相似文献/References:

[1]马建娟.布地奈德联合异丙托溴铵雾化治疗COPD 急性加重期的效果评价[J].医学信息,2018,31(07):141.[doi:10.3969/j.issn.1006-1959.2018.07.048]
　MA Jian-juan.Efficacy Evaluation of Budesonide Combined with Ipratropium Bromide in Treatment of Acute Exacerbation of COPD[J].Journal of Medical Information,2018,31(03):141.[doi:10.3969/j.issn.1006-1959.2018.07.048]
[2]罗玉霞.舒适护理在布地奈德联合氨溴索雾化吸入治疗 慢阻肺急性发作患者的效果分析[J].医学信息,2018,31(12):179.[doi:10.3969/j.issn.1006-1959.2018.12.058]
　LUO Yu-xia.Analysis of the Effect of Comfortable Nursing in the Treatment of Acute Exacerbation of Chronic Obstructive Pulmonary Disease Patients with Aerosolized Inhalation of Budesonide and Ambroxol[J].Journal of Medical Information,2018,31(03):179.[doi:10.3969/j.issn.1006-1959.2018.12.058]
[3]张明荣.孟鲁司特钠联合布地奈德治疗小儿哮喘的临床疗效分析[J].医学信息,2018,31(13):131.[doi:10.3969/j.issn.1006-1959.2018.13.038]
　ZHANG Ming-rong.Clinical Analysis of Montelukast Sodium Combined with Budesonide in the Treatment of Childhood Asthma[J].Journal of Medical Information,2018,31(03):131.[doi:10.3969/j.issn.1006-1959.2018.13.038]
[4]王 瑜.布地奈德混悬液联合特布他林治疗小儿哮喘的效果[J].医学信息,2022,35(12):184.[doi:10.3969/j.issn.1006-1959.2022.12.047]
　WANG Yu.Effect of Budesonide Suspension Combined with Terbutaline in the Treatment of Pediatric Asthma[J].Journal of Medical Information,2022,35(03):184.[doi:10.3969/j.issn.1006-1959.2022.12.047]
[5]王 雪,章 晔,李宝华.孟鲁斯特钠片与异丙托溴铵和布地奈德混悬液雾化吸入对小儿呼吸道感染性咳嗽的临床疗效[J].医学信息,2022,35(12):190.[doi:10.3969/j.issn.1006-1959.2022.12.049]
　WANG Xue,ZHANG Ye,LI Bao-hua.Clinical Effect of Montelukast Sodium Tablets Combined with Ipratropine Bromide and Budesonide Mixed Suspension Atomization Inhalation on Children with Respiratory Tract Infection Cough[J].Journal of Medical Information,2022,35(03):190.[doi:10.3969/j.issn.1006-1959.2022.12.049]
[6]周 佳,柴明思.布地奈德、异丙托溴铵气雾剂联合雾化吸入治疗对肺气肿患者肺功能及血液相关指标的影响[J].医学信息,2019,32(09):151.[doi:10.3969/j.issn.1006-1959.2019.09.050]
　ZHOU Jia,CHAI Ming-si.Effects of Budesonide and Ipratropium Bromide Aerosol Combined with Nebulized Inhalation on Pulmonary Function and Blood Related Indexes in Patients with Emphysema[J].Journal of Medical Information,2019,32(03):151.[doi:10.3969/j.issn.1006-1959.2019.09.050]
[7]韦春峥,莫 彬,莫善圆,等.孟鲁司特钠联合布地奈德治疗儿童支气管哮喘合并变应性鼻炎的临床效果[J].医学信息,2019,32(20):142.[doi:10.3969/j.issn.1006-1959.2019.20.044]
　WEI Chun-zheng,MO Bin,MO Shan-yuan,et al.Clinical Effect of Montelukast Sodium Combined with Budesonide in the Treatment of Children with Bronchial Asthma Complicated with Allergic Rhinitis[J].Journal of Medical Information,2019,32(03):142.[doi:10.3969/j.issn.1006-1959.2019.20.044]
[8]刘江海.异丙托溴铵雾化吸入治疗慢阻肺急性加重期的临床疗效[J].医学信息,2019,32(20):150.[doi:10.3969/j.issn.1006-1959.2019.20.047]
　LIU Jiang-hai.Clinical Efficacy of Ipratropium Bromide Inhalation in the Treatment of Acute Exacerbation of Chronic Obstructive Pulmonary Disease[J].Journal of Medical Information,2019,32(03):150.[doi:10.3969/j.issn.1006-1959.2019.20.047]
[9]甘 瀛.孟鲁司特钠联合布地奈德治疗小儿咳嗽变异性哮喘的疗效[J].医学信息,2019,32(12):150.[doi:10.3969/j.issn.1006-1959.2019.12.049]
　GAN Ying.Efficacy of Montelukast Sodium Combined with Budesonide in the Treatment of Cough Variant Asthma in Children[J].Journal of Medical Information,2019,32(03):150.[doi:10.3969/j.issn.1006-1959.2019.12.049]
[10]聂 志.吸入用沙丁胺醇联合布地奈德对COPD急性加重期的作用[J].医学信息,2019,32(22):105.[doi:10.3969/j.issn.1006-1959.2019.22.033]
　NIE Zhi.Effect of Inhaled Salbutamol Combined with Budesonide on Acute Exacerbation of COPD[J].Journal of Medical Information,2019,32(03):105.[doi:10.3969/j.issn.1006-1959.2019.22.033]

更新日期/Last Update: 2019-02-25