[1]李 昂,高一平,孙燕燕,等.PM2.5对儿童呼吸系统相关疾病的研究[J].医学信息,2019,32(11):29-35.[doi:10.3969/j.issn.1006-1959.2019.11.009]
 LI Ang,GAO Yi-ping,SUN Yan-yan,et al.Study on PM2.5 in Children's Respiratory Related Diseases[J].Journal of Medical Information,2019,32(11):29-35.[doi:10.3969/j.issn.1006-1959.2019.11.009]
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PM2.5对儿童呼吸系统相关疾病的研究()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
32卷
期数:
2019年11期
页码:
29-35
栏目:
综述
出版日期:
2019-06-01

文章信息/Info

Title:
Study on PM2.5 in Children's Respiratory Related Diseases
文章编号:
1006-1959(2019)11-0029-07
作者:
李 昂1高一平2孙燕燕1李 姣3陈宇洲4
1.天津市儿童医院药剂科,天津 300134; 2.天津市中心妇产科医院产科,天津 300100; 3.天津怀仁制药有限公司研发部,天津 300385; 4.天津中医药大学中药学院药剂教研室,天津 300193
Author(s):
LI Ang1GAO Yi-ping2SUN Yan-yan1LI Jiao3CHEN Yu-zhou4
1.Department of Pharmacy,Tianjin Children's Hospital,Tianjin 300134,China; 2.Department of Obstetrics,Tianjin Central Hospital of Obstetrics and Gynecology,Tianjin 300100, China; 3.Research and Development Department of Tianjin Huairen Pharmaceutical Co.,
关键词:
PM2.5来源及特征致病机制儿童呼吸系统疾病
Keywords:
Key words:PM2.5Source and characteristicsPathogenic mechanismChildrenRespiratory diseases
分类号:
R122.2;R56
DOI:
10.3969/j.issn.1006-1959.2019.11.009
文献标志码:
A
摘要:
近年来,随着我国工业快速发展,能源的高消耗,空气污染问题已成为令人担忧的环境问题之一。雾霾现象日益严重,作为雾霾中最重要的致病物质-PM2.5的污染已成为我国一个严重的环境问题。其通过炎症反应、氧化应激、诱导自噬和细胞凋亡等方式引起呼吸系统疾病。儿童正处于生长发育期,属于PM2.5高度敏感的人群之一。PM2.5可随呼吸进入患儿气管甚至肺部,导致下呼吸道感染、哮喘、鼻炎、结核等呼吸系统发病率升高。但目前尚无很好的解决办法完全消除PM2.5造成的危害,未来还需要更多的研究进一步验证PM2.5的致病机制及其与儿童呼吸系统疾病的关系,并制订有效的预防措施和治疗方案。本文就PM2.5的来源及特征、致病机制及对儿童呼吸系统相关疾病的影响进行综述,旨在为临床研究提供参考。
Abstract:
Abstract:In recent years, with the rapid development of China's industry and the high consumption of energy, air pollution has become one of the worrying environmental problems. The haze phenomenon has become increasingly serious, and the pollution of PM2.5, the most important pathogenic substance in smog, has become a serious environmental problem in China. PM2.5 causes respiratory diseases through inflammatory reactions, oxidative stress, induced autophagy, and apoptosis. The child is in the growth stage and is one of the highly sensitive people in PM2.5. PM2.5 can enter the child's trachea and even the lungs with breathing, leading to an increase in the incidence of respiratory diseases such as lower respiratory tract infections, asthma, rhinitis, and tuberculosis. However, there is no good solution to completely eliminate the harm caused by PM2.5. In the future, more research is needed to further verify the pathogenic mechanism of PM2.5 and its relationship with respiratory diseases in children, and to develop effective preventive measures. And treatment options. This article reviews the sources and characteristics of PM2.5, the pathogenesis and effects on children's respiratory related diseases, and aims to provide reference for clinical research.

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更新日期/Last Update: 2019-06-01