[1]关 楠.平凉市儿童过敏性紫癜相关环境因素调查研究[J].医学信息,2019,(11):144-146.[doi:10.3969/j.issn.1006-1959.2019.11.042]
 GUAN Nan.Investigation on Environmental Factors Related to Children's Henoch-Schonlein Purpura in Pingliang City[J].Medical Information,2019,(11):144-146.[doi:10.3969/j.issn.1006-1959.2019.11.042]
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平凉市儿童过敏性紫癜相关环境因素调查研究()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
期数:
2019年11期
页码:
144-146
栏目:
调查分析
出版日期:
2019-06-01

文章信息/Info

Title:
Investigation on Environmental Factors Related to Children's Henoch-Schonlein Purpura in Pingliang City
文章编号:
1006-1959(2019)11-0144-03
作者:
关 楠
平凉市人民医院儿科,甘肃 平凉 744000
Author(s):
GUAN Nan
Department of Pediatrics,Pingliang People's Hospital,Pingliang 744000,Gansu,China
关键词:
过敏性紫癜平凉市环境因素
Keywords:
Key words:Henoch-Schonlein purpuraPingliang cityEnvironmental factors
分类号:
R725.5
DOI:
10.3969/j.issn.1006-1959.2019.11.042
文献标志码:
A
摘要:
目的 探讨平凉市儿童过敏性紫癜(HSP)发病与家庭居住环境、空气质量等环境因素之间的关系。方法 收集2016年1月~2018年12月平凉市范围内年龄≤14岁的314例HSP门诊及住院患儿设为病例组,随机抽取同期在我院体检且年龄≤14岁的健康儿童200例设为对照组,统计并分析不同年龄、性别、季度等条件下HSP患儿的发病情况及居住条件对其发病的影响。结果 病例组HSP患儿发病年龄以4~10岁居多,各年龄段患儿的男女比例,差异无统计学意义(P>0.05);病例组HSP患儿各季度发病率由高到低依次为春季、冬季、夏季、秋季(34.71%、34.93%、18.15%、12.74%),与平凉市各季度空气优良排名相反(81.92%、82.97%、87.18%、97.46);病例组家中独生子女和房间勤通风比例低于对照组,家中被动吸烟和饲养动物的比例高于对照组,差异有统计学意义(P<0.05)。结论 环境因素对平凉市HSP患儿发病具有一定的影响作用,空气污染程度、非独生子女家庭、家中被动吸烟、家中饲养动物及房屋通风情况均为潜在的影响因素。故减少儿童,特别是学龄前及学龄儿童在污染物中的暴露时间及与少感染原、过敏原等的接触机会,有助于儿童HSP的预防。
Abstract:
Abstract:Objective To investigate the relationship between the incidence of Henoch-Schonlein purpura (HSP) in children and the environmental factors such as family living environment and air quality in Pingliang City.Methods A total of 314 HSP outpatients and hospitalized children aged ≤14 years in Pingliang City from January 2016 to December 2018 were enrolled as the case group. 200 healthy children aged ≤14 years old were randomly selected from our hospital. As a control group, statistics and analysis of the incidence of HSP children and the impact of living conditions on their incidence under different age, gender, quarter and other conditions.Results The age of onset of HSP in the case group was mostly 4 to 10 years old. There was no significant difference in the ratio of male to female in all age groups (P>0.05). The incidence of HSP in the case group was from high to low. Spring, winter, summer, autumn (34.71%, 34.93%, 18.15%, 12.74%), contrary to Pingliang City's excellent air rankings in each quarter (81.92%, 82.97%, 87.18%, 97.46); the only child and room in the case group the proportion of diligent ventilation was lower than that of the control group. The proportion of passive smoking and feeding animals in the family was higher than that in the control group,the difference was statistically significant (P<0.05).Conclusion Environmental factors have a certain impact on the incidence of HSP in Pingliang City. The degree of air pollution, non-only child families, passive smoking in the home, domestic animals and ventilation are potential factors. Therefore, reducing the exposure time of children, especially preschool and school-age children, to pollutants and exposure to less infectious agents, allergens, etc., contribute to the prevention of HSP in children.

参考文献/References:

[1]Luo S,Liang G,Zhang P,et al.Aberrant histone modifications in peripheral blood mononuclear cells from patients with HenochSch nlein purpura[J].Clin Immunol,2013,146(3):165-175. [2]王卫平,毛萌,李廷玉,等.儿科学[M].第8版.北京:人民卫生出版社,2014:190-192. [3]常克,范涛,邱继春,等.儿童过敏性紫瘫相关因素调查研究[J].辽宁中医药大学学报,2016,18(5):5-8. [4]陈洪.静注丙种球蛋白治疗过敏性紫癜疗效观察[J].中国当代医药,2009,16(4):175-176. [5]范涛.150例儿童过敏性紫癜相关因素调查研究[D].成都中医药大学,2014:9-10. [6]姜武林,朱焰,魏亚新.过敏性紫癜患儿链球菌感染的检测与分析[J].临床医学,2004,24(1):53. [7]曹桂红.过敏性紫癜性肾炎发病因素相关性研究及护理对策[J].中华全科医学,2015,13(1):126-128.

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更新日期/Last Update: 2019-06-01