[1]冯瑞丰.阿奇霉素治疗急性细菌性下呼吸道感染的 有效性和安全性评价[J].医学信息,2019,32(11):152-153.[doi:10.3969/j.issn.1006-1959.2019.11.045]
　FENG Rui-feng.Evaluation of the Efficacy and Safety of Azithromycin in the Treatment of Acute Bacterial Lower Respiratory Tract Infections[J].Journal of Medical Information,2019,32(11):152-153.[doi:10.3969/j.issn.1006-1959.2019.11.045]
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阿奇霉素治疗急性细菌性下呼吸道感染的 有效性和安全性评价()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
32卷
期数:
2019年11期
页码:
152-153
栏目:
药物与临床
出版日期:
2019-06-01

文章信息/Info

Title:
Evaluation of the Efficacy and Safety of Azithromycin in the Treatment of Acute Bacterial Lower Respiratory Tract Infections
文章编号:
1006-1959（2019）11-0152-02
作者:
冯瑞丰
天津市宝坻区人民医院/天津医科大学宝坻临床学院呼吸科，天津 301800
Author(s):
FENG Rui-feng
Tianjin Baodi District People's Hospital/Department of Respiratory,Baodi Clinical College,Tianjin Medical University, Tianjin 301800,China
关键词:
阿奇霉素; 急性细菌性下呼吸道感染; 左氧氟沙星
Keywords:
Key words：Azithromycin; Acute bacterial lower respiratory tract infection; Levofloxacin
分类号:
R56
DOI:
10.3969/j.issn.1006-1959.2019.11.045
文献标志码:
A
摘要:
目的 对本院急性细菌性下呼吸道感染患者运用阿奇霉素治疗，分析其有效性和安全性。方法 回顾性分析2016年6月~2018年6月我院收治的96例急性细菌性下呼吸道感染患者临床资料，随机分为两组，其中实验组患者为48例，采用阿奇霉素治疗；对照组48例患者采用左氧氟沙星治疗，比较两组患者的临床疗效，临床症状持续时间以及不良反应发生情况。结果 实验组治疗总有效率（95.83%）高于对照组（70.83%），差异具有统计学意义（P＜0.05）；实验组肺啰音、发热、咳嗽症状持续时间均短于对照组，差异具有统计学意义（P＜0.05）；实验组不良反应发生率低于对照组（P＜0.05）。结论 采用阿奇霉素治疗急性细菌性下呼吸道感染疗效确切，不良反应少，是临床上治疗急性细菌性下呼吸道感染安全性抗生素之一。
Abstract:
Abstract：Objective To analyze the efficacy and safety of azithromycin in patients with acute bacterial lower respiratory tract infection in our hospital.Methods The clinical data of 96 patients with acute bacterial lower respiratory tract infection admitted to our hospital from June 2016 to June 2018 were retrospectively analyzed. They were randomly divided into two groups, including 48 patients in the experimental group and treated with azithromycin,48 patients in the control group were treated with levofloxacin, and the clinical efficacy, duration of clinical symptoms, and adverse reactions were compared between the two groups.Results The total effective rate of the experimental group (95.83%) was higher than that of the control group (70.83%),the difference was statistically significant (P<0.05). The duration of pulmonary snoring, fever and cough in the experimental group was shorter than that of the control group,the difference was statistically significant(P<0.05);the incidence of adverse reactions in the experimental group was lower than that in the control group(P<0.05).Conclusion Azithromycin is effective in the treatment of acute bacterial lower respiratory tract infections with few adverse reactions. It is one of the safe antibiotics for the treatment of acute bacterial lower respiratory tract infections.

参考文献/References:

[1]高健.五水头孢唑林钠(新泰林)治疗下呼吸道急性细菌性感染的临床研究[J].中国医药指南,2017,15(22):29,31. [2]吴立强,鲍缦夕,陈小蕾,等.加替沙星联合喜炎平治疗COPD急性加重期下呼吸道细菌感染临床观察[J].武警后勤学院学报(医学版),2016,25(2):147-148. [3]周珺,熊英,段招军.急性呼吸道感染监测[J].疾病监测,2015,30(3):245-250. [4]吴超男,陈娜娜,李玉琴.阿奇霉素研究进展[J].泰山医学院学报,2016,37(11):1317-1320. [5]崔虹.左氧氟沙星不良反应分析及临床合理用药[J].数理医药学杂志,2016,29(3):402-403.

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更新日期/Last Update: 2019-06-01