[1]赵 萍.初诊青年2型糖尿病临床特点及危险因素分析[J].医学信息,2019,32(16):102-104.[doi:10.3969/j.issn.1006-1959.2019.16.032]
 ZHAO Ping.Analysis of Clinical Features and Risk Factors of Type 2 Diabetes in Newly Diagnosed Youth[J].Journal of Medical Information,2019,32(16):102-104.[doi:10.3969/j.issn.1006-1959.2019.16.032]
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初诊青年2型糖尿病临床特点及危险因素分析()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
32卷
期数:
2019年16期
页码:
102-104
栏目:
临床研究
出版日期:
2019-08-15

文章信息/Info

Title:
Analysis of Clinical Features and Risk Factors of Type 2 Diabetes in Newly Diagnosed Youth
文章编号:
1006-1959(2019)16-0102-03
作者:
赵 萍
广西医科大学第四附属医院内分泌科,广西 柳州 545005
Author(s):
ZHAO Ping
Department of Endocrinology,the Fourth Affiliated Hospital of Guangxi Medical University, Liuzhou 545005,Guangxi,China
关键词:
青年2型糖尿病体重指数血脂男性
Keywords:
Key words:YouthType 2 diabetesBody mass indexBlood lipidsMale
分类号:
R587.1
DOI:
10.3969/j.issn.1006-1959.2019.16.032
文献标志码:
A
摘要:
目的 明确青年初诊2型糖尿病的临床特点并探讨相关危险因素,为预防高危因素青年人发生2型糖尿病提供理论依据。方法 选择我院内分泌科2017年1月~2018年3月住院的313例初诊2型糖尿病患者,以40岁为界将其分为青年组及非青年组,分析患者的临床特点及危险因素。结果 青年组男性构成率为75.76%,非青年组男性构成率为55.87%,两组性别构成率比较,差异有统计学意义(P<0.05);青年组收缩压(128.88±17.97)mmHg低于非青年组(137.47±19.44)mmHg,差异有统计学意义(P<0.05);青年组体重指数(26.02±4.80)kg/m2高于非青年组(24.52±3.41)kg/m2,差异具有统计学意义(P<0.05);青年组甘油三酯(3.62±3.44)mmol/L高于非青年组(2.87±3.35)mmol/L,差异有统计学意义(P<0.05);青年组高密度脂蛋白(1.03±0.35)mmol/L低于非青年组(1.14±0.37)mmol/L,差异有统计学意义(P<0.05)。初诊2型糖尿病为青年人的危险因素为性别(OR=2.07,95%CI:1.09~3.93,P<0.05)、BMI(OR=2.10,95%CI:1.14~3.18,P<0.05)及HDL-C(OR=1.98,95%CI:1.11~3.52,P<0.05)。结论 男性、超重及肥胖、低高密度脂蛋白是青年人发生2型糖尿病的危险因素。
Abstract:
Abstract:Objective To determine the clinical characteristics of newly diagnosed type 2 diabetes in young people and to explore related risk factors, so as to provide a theoretical basis for prevention of type 2 diabetes in young people with high risk factors.Methods 313 patients with newly diagnosed type 2 diabetes who were hospitalized from January 2017 to March 2018 in our hospital were divided into young and non-youth groups by age 40, and the clinical characteristics and risk factors were analyzed.Results The male composition rate was 75.76% in the youth group and 55.87% in the non-youth group. The gender composition rate was statistically significant (P<0.05). The young group systolic blood pressure (128.88±17.97) mmHg lower than the non-youth group (137.47±19.44) mmHg, the difference was statistically significant (P<0.05); the body mass index (26.02±4.80) kg/m2 in the young group was higher than that in the non-youth group (24.52±3.41) kg/m2, the difference was statistically significant (P<0.05); Triglyceride (3.62±3.44) mmol/L was higher than non-youth group (2.87±3.35) mmol/L, the difference was statistically significant (P<0.05); high density lipoprotein (1.03±0.35) mmol/L lower than the non-youth group (1.14±0.37) mmol/L, the difference was statistically significant (P<0.05). The risk factors for newly diagnosed type 2 diabetes were younger (OR=2.07, 95%CI: 1.09~3.93,P<0.05), BMI (OR=2.10, 95%CI: 1.14~3.18,P<0.05) and HDL-C (OR=1.98,95%CI:1.11 to 3.52,P<0.05).Conclusion Male, overweight and obese, low-density lipoprotein is risk factor for developing type 2 diabetes in young adults.

参考文献/References:

[1]Bin Z,Yuan L,Kaveh H,et al.Supplementary Material:Worldwide trends in diabetes since 1980:a pooled analysis of 751 population-based studies with 4.4 million participants[J].The Lancet,2016,387(10027):1513-1530. [2]Aguiree F,Brown A,Cho NH,et al.IDF Diabetes Atlas:sixth edition[J].International Diabetes Federation,2013(6):155. [3]赵连利,刘可魂,王永森.沧州市青年2型糖尿病患病率和知晓率调查[J].临床荟萃,2016,31(3):334-335. [4]赵艳芳,王卓群,杨静,等.中国2013年18~49岁育龄妇女2型糖尿病患病率、知晓率、治疗率和控制率状况分析[J].中华流行病学杂志,2018,39(2):213-217. [5]张杜丹,唐迅,靳丹瑶,等.中国成年人糖尿病患病率Meta分析[J].中华流行病学杂志,2018,39(6):852-857. [6]中国高血压防治指南修订委员会.中国高血压防治指南2010[J].中华心血管病杂志,2011,39(7):579-616. [7]中国肥胖问题工作组.中国成人超重与肥胖症预防与控制指南(节录)[J].营养学报,2004,26(1):1-4. [8]中国成人血脂异常防治指南修订联合委员会.中国成人血脂异常防治指南(2016年修订版)[J].中国循环杂志,2016,31(10):937-950. [9]Liu XX,Yu CH,Wang YB,et al.Trends in the Incidence and Mortality of Diabetes in China from 1990 to 2017:A Joinpoint and Age-Period-Cohort Analysis[J].Int J Environ Res Public Health,2019,16(1):158. [10]Allan CA,McLachlan RI.Androgens and obesity[J].Curr Opin Endocrinol Diabetes Obes,2010,17(3):224-232. [11]Brand JS,van der Tweel I,Grobbee DE,et al.Testosterone,sex hormone-binding globulin and the metabolic syndrome:a systematic review and meta-analysis of observational studies[J].Int J Epidemiol,2011,40(1):189-207. [12]Gikas A,Sotiropoulos A,Panagiotakos D,et al.Prevalence,and associated risk factors,of self-reported diabetes mellitus in a sample of adult urban population in Greece:MEDICAL Exit Poll Research in Salamis(MEDICAL EXPRESS 2002)[J].BMC Public Health,2004(4):2. [13]Mokdad AH,Ford ES,Bowman BA,et al.Diabetes trends in the U.S.:1990-1998[J].Diabetes Care,2000,23(9):1278-1283. [14]Gonzalez EL,Johansson S,Wallander MA,et al.Trends in the prevalence and incidence of diabetes in the UK:1996-2005[J].J Epidemiol Community Health,2009,63(4):332-336. [15]Boffetta P,McLerran D,Chen Y,et al.Body mass index and diabetes in Asia:a cross-sectional pooled analysis of 900,000 individuals in the Asia cohort consortium[J].PLoS One,2011,6(6):e19930. [16]安雅莉,高研,朱倩,等.不同体重指数新诊断2型糖尿病患者胰岛素分泌和胰岛素抵抗状况调查[J].中华医学杂志,2009,89(16):1117-1121. [17]林珊珊,郭丽敏,佘其美,等.新诊断早发2型糖尿病心脑血管疾病风险分析[J].中国当代医药,2016,23(20):56-59. [18]庞邵杰,满青青,宋爽,等.不同血糖代谢状态下老年人血脂与胰岛素抵抗的关系研究[J].中华预防医学杂志,2018,52(6):629-635.

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更新日期/Last Update: 2019-08-15