[1]尤 鑫,崔洪艳.PDGF与子痫前期相关性的研究进展[J].医学信息,2019,(17):53-56.[doi:10.3969/j.issn.1006-1959.2019.17.017]
 YOU Xin,CUI Hong-yan.Advances in Research on the Relationship between PDGF and Preeclampsia[J].Medical Information,2019,(17):53-56.[doi:10.3969/j.issn.1006-1959.2019.17.017]
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PDGF与子痫前期相关性的研究进展()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
期数:
2019年17期
页码:
53-56
栏目:
综述
出版日期:
2019-09-01

文章信息/Info

Title:
Advances in Research on the Relationship between PDGF and Preeclampsia
文章编号:
1006-1959(2019)17-0053-04
作者:
尤 鑫崔洪艳
天津市中心妇产科医院妇产科,天津 300100
Author(s):
YOU XinCUI Hong-yan
Gynecology Department,Tianjin Central Hospital of Obstetrics and Gynecology,Tianjin 300100,China
关键词:
子痫前期血小板源性生长因子动脉粥样硬化病变不良妊娠结局
Keywords:
Key words:PreeclampsiaPlatelet-derived growth factorAtherosclerotic lesionsAdverse pregnancy outcomes
分类号:
R714.24+5
DOI:
10.3969/j.issn.1006-1959.2019.17.017
文献标志码:
A
摘要:
子痫前期是妊娠期特有的疾病,是一种多系统疾病,其特征在于高血压伴随母体或胎儿一种或多种其他器官系统损害。血小板源性生长因子(PDGF)是一种促有丝分裂剂,涉及细胞的迁徙、增殖、新血管形成及动脉粥样硬化病变的发生、发展。PDGF适度分泌释放对是否发生病理性妊娠极其关键,过度分泌可导致子痫前期胎盘血管病变。现将近年来与子痫前期有关的PDGF的研究进行总结。
Abstract:
Abstract:Preeclampsia is a disease specific to pregnancy and is a multi-system disease characterized by hypertension accompanied by damage to one or more other organ systems of the mother or fetus. Platelet-derived growth factor (PDGF) is a mitogenic agent involved in cell migration, proliferation, neovascularization, and the development and progression of atherosclerotic lesions. Moderate secretion of PDGF is critical for the presence or absence of pathological pregnancy, and excessive secretion can lead to pre-eclamptic placental vasculopathy. The recent studies on PDGF related to preeclampsia are summarized.

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更新日期/Last Update: 2019-09-01